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Probable adapter protein involved in signaling pathways. Zusätzlich bieten wir Ihnen Target of Myb1 (Chicken)-Like 1 Antikörper (88) und und viele weitere Produktgruppen zu diesem Protein an.
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TOM1L1 enhances ERBB2 (zeige ERBB2 Proteine)-induced cell invasiveness by promoting invadopodia formation and MT1-MMP (zeige MMP14 Proteine) trafficking to the plasma membrane.
whereas TOM1L1 depletion only slightly affected SRC (zeige SRC Proteine)-induced proliferation of colorectal cancer cells in vitro, it drastically decreased tumor growth in xenografted nude mice.
This pattern of Srcasm expression suggests that it may act as a negative regulator in esophageal squamous cell carcinoma cell signaling
results imply that TOM1L has a mitogenic effect in Jurkat T-cells and is involved in a novel cell signaling pathway that is crucial for the IL-2 (zeige IL2 Proteine) production and STAT3 (zeige STAT3 Proteine) expression
Srcasm plays a role in linking EGF receptor (zeige EGFR Proteine)- and SFK-dependent signaling to differentiation in keratinocytes
Tom1L1 could act as an intermediary between signaling and degradative pathways.
study found that not only the PTAP sequence in the GAT (zeige GLYAT Proteine) domain but also the PSAP (zeige PSAP Proteine) sequence in the C-terminal region of Tom1L1 is responsible for its interaction with the UEV domain of Tsg101 (zeige TSG101 Proteine) and competes with the HIV-1 Gag protein for the Tsg101 (zeige TSG101 Proteine) interaction
All multicentric and nodular basal cell carcinomas displayed a prominent loss of Srcasm staining in association with a marked increase in Ki-67 (zeige MKI67 Proteine) staining.
Participation of Tom1L1 in EGF (zeige EGF Proteine)-stimulated endocytosis of EGF receptor (zeige EGFR Proteine).
Tom1L1 defines a novel mechanism for regulation of Src (zeige SRC Proteine) family of protein-tyrosine kinases mitogenic signaling induced by growth factors.
Srcasm may act as a molecular "rheostat" for activated Src (zeige SRC Proteine) family tyrosine kinases
Tom1L1-clathrin heavy chain (CHC) complex negatively regulates the level of SFK in caveolae needed for the induction of DNA synthesis.
Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).
target of myb1-like 1
, target of myb1 (chicken)-like 1
, TOM1-like protein 1
, TOM1-like protein 1-like
, Src activating and signaling molecule
, src-activating and signaling molecule protein
, target of Myb-like protein 1
, target of myb 1-like 1
, Src-activating and signaling molecule protein
, Target of Myb-like protein 1
, Jerry protein