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TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3\; MIM 300506) (Kester et al., 1999 [PubMed 10488076]\; Fiorenza et al., 2001 [PubMed 11707329]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen TSC22D4 Antikörper (28) und und viele weitere Produktgruppen zu diesem Protein an.
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Data suggest transcription factor TSC22D4 inhibition as an insulin sensitizing option in diabetes therapy.
tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.
Long form of TSC22DF is evolutionarily conserved and has growth-regulating potential.
Liver-specific ablation of TSC22D4 triggered hypertriglyceridemia through the induction of hepatic VLDL secretion.
In vitro TSC22D4 silencing with small interfering (si)RNAs blocks granule cell differentiation and inhibits neurite elongation in neuroblastoma cells, pinpointing the relevance of this protein to granule cell differentiation.
Thg-1 pit is relevant to specification, proliferation/migration, differentiation, and mature function of granule/interneuron cells in different brain districts [Thg-1 pit]
TSC22D4 is stably upregulated by hyperosmolality in mIMCD3 cells and increased in renal papilla compared with cortex.
TSC-22 is a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD
Results suggest that THG-1pit is involved in the induction of granule neuron apoptosis.
TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3\; MIM 300506) (Kester et al., 1999
TSC22 domain family, member 4
, TSC22 domain family 4
, TSC22 domain family protein 4
, TSC22-related-inducible leucine zipper protein 2
, tsc-22-like protein THG-1
, TSC22-related inducible leucine zipper 2