anti-TAP Binding Protein-Like (TAPBPL) Antikörper

Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP\; see MIM 170260) in the endoplasmic reticulum (ER). Zusätzlich bieten wir Ihnen TAPBPL Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TAPBPL 55080 Q9BX59
TAPBPL 213233 Q8VD31
TAPBPL    
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Top anti-TAPBPL Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Tapbpl Antibody Titration: 1.0 ug/ml Positive Control: Mouse Brain 100 μL 2 bis 3 Tage
$319.00
Details
Human Maus Unkonjugiert IF, IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$522.50
Details
Human Kaninchen Unkonjugiert EIA, WB TAPBPL Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TAPBPL antibody detected the TAPBPL protein (arrow). 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Maus Unkonjugiert IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$522.50
Details
Hund Maus Unkonjugiert IF, IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$522.50
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$537.17
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Human Maus Unkonjugiert WB 100 μL 11 bis 14 Tage
$522.50
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Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$581.17
Details
Human Maus Unkonjugiert ELISA, WB TAPBPL monoclonal antibody (M02), clone 6E3 Western Blot analysis of TAPBPL expression in A-431 . Detection limit for recombinant GST tagged TAPBPL is approximately 0.03ng/ml as a capture antibody. 100 μg 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert WB Western Blot analysis of TAPBPL expression in transfected 293T cell line by TAPBPL MaxPab polyclonal antibody.Lane 1: TAPBPL transfected lysate(51.48 KDa).Lane 2: Non-transfected lysate. 50 μL 11 bis 12 Tage
$440.00
Details

Weitere Antikörper gegen TAPBPL Interaktionspartner

Human TAP Binding Protein-Like (TAPBPL) Interaktionspartner

  1. The results demonstrate an inverse relationship between MHC-I peptide occupancy and TAPBPR binding affinity, wherein the lifetime and structural features of transiently bound peptides control the regulation of a conformational switch located near the TAPBPR binding site, which triggers TAPBPR release.

  2. Data suggest therapeutic potential of TAP binding protein like tapasin-related protein (TAPBPR) manipulation to increase tumour immunogenicity.

  3. soluble TAPBPR, consisting of the luminal domain alone, added to intact cells, also functions as an effective peptide editor on surface MHC I molecules.

  4. this study reports the crystal structure of MHC I in complex with the peptide editor TAPBPR (TAP-binding protein-related), a tapasin homolog.

  5. this study presents the x-ray structure of the TAPBPR-MHC I complex, which delineates the central step of catalysis.

  6. The authors identify an interaction between TAPBPR and UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1), a folding sensor in the calnexin/calreticulin quality control cycle that is known to regenerate the Glc1Man9GlcNAc2 moiety on glycoproteins. The results suggest the formation of a multimeric complex, dependent on a conserved cysteine at position 94 in TAPBPR, in which TAPBPR promotes the association of UGT1 with p

  7. It is now clear there are two MHC class I specific peptide editors, tapasin and TAPBPR, intimately involved in controlling peptide presentation to the immune system.

  8. These results support a role of TAPBPR in stabilizing peptide-receptive conformation(s) of MHC-I, permitting peptide editing.

  9. TAPBPR is a new player in the MHC class I presentation pathway. (Review)

  10. The longer TAPBPR protein interacted with MHC class I but was attenuated in its ability to down-regulate surface expression of MHC class I.

  11. the data indicate that TAPBPR and tapasin bind in a similar orientation to the same face of MHC class I.

  12. The function of the tapasin-related protein, TAPBPR, was investigated.

  13. HLA-I, TAP1, CNX, LMP7, Erp57, Tapasin and ERAP1 were down-regulated in 68%, 44%, 48%, 40%, 52%, 32% and 20% of esophageal squamous cell carcinoma lesions then, respectively.

Mouse (Murine) TAP Binding Protein-Like (TAPBPL) Interaktionspartner

  1. Focuses on cloning and characterization of human TAPBP-R but also identifies the mouse ortholog Tapbpl.

TAPBPL Antigen-Profil

Protein Überblick

Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP\; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.

Genbezeichner und Symbole assoziert mit TAPBPL

  • TAP binding protein like (TAPBPL) Antikörper
  • TAP binding protein-like (Tapbpl) Antikörper
  • BC017613 Antikörper
  • TAPBP-R Antikörper
  • TAPBPL Antikörper
  • TAPBPL-R Antikörper
  • Tapbplr Antikörper
  • TAPBPR Antikörper

Bezeichner auf Proteinebene für TAPBPL

TAP binding protein-like , TAP binding protein related , TAP-binding protein-like , TAP-binding protein-related protein , TAPASIN-R , tapasin-like , tapasin-related protein , TAPBP-R

GENE ID SPEZIES
451781 Pan troglodytes
486727 Canis lupus familiaris
55080 Homo sapiens
529141 Bos taurus
213233 Mus musculus
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