anti-Stathmin-Like 2 (STMN2) Antikörper

STMN2 encodes a member of the stathmin family of phosphoproteins. Zusätzlich bieten wir Ihnen Stathmin-Like 2 Proteine (10) und Stathmin-Like 2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
STMN2 11075 Q93045
STMN2 20257 P55821
STMN2 84510 P21818
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Top anti-Stathmin-Like 2 Antikörper auf antikoerper-online.de

Showing 10 out of 122 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Maus Ziege Unkonjugiert ELISA, WB Antibody (0.5µg/ml) staining of Mouse Foetal Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 bis 7 Tage
$429.84
Details
Huhn Kaninchen Unkonjugiert WB Western blot analysis of STMN2 expression in SHSY5Y (A), NIH3T3 (B), A549 (C), rat brain (D) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain, antibody was diluted at 1:100. 100 μL Verfügbar
$363.46
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image STMN2 antibody detects STMN2 protein at cytoplasm on human liver carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded liver carcinoma. STMN2 antibody , dilution: 1:250. ICC/IF Image Immunofluorescence analysis of methanol-fixed A549, using STMN2, antibody at 1:500 dilution. 100 μL 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti STMN2/SCG10 Polyclonal Antibody, Unconjugated (ABIN703616) at 1:200 followed by conjugation to the secondary antibody and DAB staining Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 100 μL 3 bis 7 Tage
$317.90
Details
Huhn Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with STMN2 antibody ABIN461978 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine, Myenteric Plexus (formalin-fixed, paraffin-embedded) stained with STMN2 antibody ABIN461978 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis STMN2 (Phospho-Ser73) using PMA treated Jurkat whole cell lysates 100 μL 11 bis 12 Tage
$450.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis STMN2 using mouse liver lysates ABIN6279860 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 bis 12 Tage
$390.77
Details
Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg 4 bis 8 Tage
$462.00
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of Stathmin-2 / STMN2 (C-term) in Jurkat cell line lysates (35ug/lane). This demonstrates the STMN2 antibody detected the STMN2 protein (arrow). 0.4 mL 6 bis 8 Tage
$484.00
Details

Am meisten referenzierte anti-Stathmin-Like 2 Antikörper

  1. Cow (Bovine) Polyclonal STMN2 Primary Antibody für ICC, IF - ABIN4356489 : Shin, Cho, Beirowski, Milbrandt, Cavalli, DiAntonio: Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. in Neuron 2012 (PubMed)
    Show all 18 Pubmed References

  2. Mammalian Monoclonal STMN2 Primary Antibody für ISt, IHC - ABIN1304947 : Sobczak, Debowska, Blazejczyk, Kreutz, Kuznicki, Wojda: Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth. in Biochimica et biophysica acta 2011 (PubMed)
    Show all 5 Pubmed References

  3. Dog (Canine) Polyclonal STMN2 Primary Antibody für ELISA, WB - ABIN546837 : Bahn, Mimmack, Ryan, Caldwell, Jauniaux, Starkey, Svendsen, Emson: Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study. in Lancet 2002 (PubMed)

Weitere Antikörper gegen Stathmin-Like 2 Interaktionspartner

Zebrafish Stathmin-Like 2 (STMN2) Interaktionspartner

  1. Zebrafish studies further demonstrated an epistatic interaction between KBP and SCG10 in vivo.

  2. Results provide a starting point for future studies that will investigate the in vivo function of SCG10 orthologues in zebrafish neural development.

Human Stathmin-Like 2 (STMN2) Interaktionspartner

  1. expression of STMN2, which encodes a microtubule regulator, declined after TDP-43 knockdown and TDP-43 mislocalization as well as in patient-specific motor neurons and postmortem patient spinal cord. STMN2 loss upon reduced TDP-43 function was due to altered splicing, which is functionally important, as we show STMN2 is necessary for normal axonal outgrowth and regeneration.

  2. premature polyadenylation-mediated reduction in stathmin-2 is a hallmark of ALS-FTD that functionally links reduced nuclear TDP-43 function to enhanced neuronal vulnerability.

  3. RARB and STMN2 polymorphisms were not associated with sporadic CJD in the Korean population.

  4. PAK4-SCG10 signaling occurs in gastric cancer cell invasion.

  5. STMN and SCG10 are similarly targeted by JNK but there are clear differences in JNK recognition and phosphorylation of the closely related family member, SCLIP.

  6. CaMy1 via SCG10 couples Ca(2+) signals with the dynamics of microtubules during neuronal outgrowth in the developing brain.

  7. SCG10 is upregulated in the IKAP/Elp1-deficient familial dysautonomia cerebrum lending support to the concept that SCG10 elevation can alter the microtubule organization and dynamics

  8. Overexpression of SCG10 is associated with Liver Fibrosis.

  9. RGS6 interacts with this protein and promotes neuronal differentiation; role of the G gamma subunit-like (GGL) domain of RGS6

  10. STMN2 is required for maintaining the anchorage-independent growth state of beta-catenin/TCF-activated hepatoma cells

  11. activity at opposite microtubule ends may play role role in regulating growth cone microtubules; ability to promote plus end growth may facilitate microtubule extension; ability to destabilize minus ends may provide tubulin for net plus end elongation

  12. Review proposes a model reconciling the microtubule regulatory properties of superior cervical ganglion protein 10 with its role as a c-Jun N-terminal kinase 1 (JNK1) effector of regeneration.

  13. BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.

  14. SCLIP and SCG10 were colocalized to the Golgi apparatus of chromaffin cells in vivo and shared localization with CHGA as it transited the Golgi.

  15. STMN2 appears a novel marker of osteogenesis and osteoblast per se, that could play a role in the regulation of the adipocyte/osteoblast balance.

  16. SCG10 acts as an effector downstream of Rnd1 to regulate axon extensions by modulating microtubule organization.

Mouse (Murine) Stathmin-Like 2 (STMN2) Interaktionspartner

  1. autophagy induction stabilized microtubules by degrading SCG10, a microtubule disassembly protein in neurons. In mice with spinal cord injury, local administration of a specific autophagy-inducing peptide, Tat-beclin1, to lesion sites markedly attenuated axonal retraction of spinal dorsal column axons and cortical spinal tract and promoted regeneration of descending axons following long-term observation

  2. SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface.

  3. This study demonstrated that axonal injury induces a dynamic regulation of SCG10 protein levels with selective accumulation in proximal axon segments.

  4. JNK phosphorylation targets SCG10 for degradation.

  5. SCG10 is not directly implicated in Hirschsprung diseased evelopment

  6. the Rarb region of Mmu14 and Stmn2, but not Cr1 or Clu or Picalm have roles in prion disease

  7. These findings indicate that the phosphorylation of SCG10 by JNK1 is a fundamental mechanism that governs the transition from the multipolar stage and the rate of neuronal cell movement during cortical development.

  8. KBP binds exclusively to microtubule associated or related proteins, specifically SCG10.

Stathmin-Like 2 (STMN2) Antigen-Profil

Protein Überblick

This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

Genbezeichner und Symbole assoziert mit STMN2

  • stathmin 2 (stmn2) Antikörper
  • stathmin 2 (STMN2) Antikörper
  • stathmin 2b (stmn2b) Antikörper
  • stathmin-2-like (LOC100226401) Antikörper
  • stathmin-2 (Tsp_05441) Antikörper
  • stathmin-like 2 (Stmn2) Antikörper
  • stathmin 2 (Stmn2) Antikörper
  • AI159727 Antikörper
  • MGC89837 Antikörper
  • Scg10 Antikörper
  • Scgn10 Antikörper
  • Stmb2 Antikörper
  • stmn2 Antikörper
  • stmn2c Antikörper
  • zgc:110132 Antikörper

Bezeichner auf Proteinebene für STMN2

stathmin-like 2 , stathmin-like 2c , SCG10a , stathmin-2 , superiorcervical ganglia, neural specific 10 , neuron-specific growth-associated protein , neuronal growth-associated protein (silencer element) , superior cervical ganglia, neural specific 10 , superior cervical ganglion-10 protein , stathmin 2

GENE ID SPEZIES
448716 Xenopus (Silurana) tropicalis
464247 Pan troglodytes
100003563 Danio rerio
100156768 Sus scrofa
100226401 Taeniopygia guttata
10913268 Trichinella spiralis
11075 Homo sapiens
20257 Mus musculus
84510 Rattus norvegicus
477918 Canis lupus familiaris
534991 Bos taurus
396095 Gallus gallus
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