Spire Homolog 1 (Drosophila) Proteine (SPIRE1)

Spire proteins, such as SPIRE1, are highly conserved between species. Zusätzlich bieten wir Ihnen Spire Homolog 1 (Drosophila) Antikörper (27) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SPIRE1 68166  
SPIRE1 56907 Q08AE8
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Top Spire Homolog 1 (Drosophila) Proteine auf antikoerper-online.de

Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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SPIRE1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu Spire Homolog 1 (Drosophila) (SPIRE1) Interaktionspartnern

Mouse (Murine) Spire Homolog 1 (Drosophila) (SPIRE1) Interaktionspartner

  1. Spire-1 is specifically recruited at invadosomes and is part of a multi-molecular complex containing Src kinase, the formin mDia1 and actin.

  2. analysis of the molecular basis of the Spir1/formin-2 interaction

  3. Spire1 and Spire2 drive two critical steps of asymmetric oocyte division.

  4. By analyzing the expression of the spir-1 gene it was shown that spir-1 and formin-2 have a nearly identical expression pattern during mouse embryogenesis and in the adult brain.

Human Spire Homolog 1 (Drosophila) (SPIRE1) Interaktionspartner

  1. interferes with bacterial binding in Salmonella typhimurium host cell invasion

  2. Data suggest formin homology domain (FH2) of Fmn2 binds actin at filament barbed end as weak capper and plays a role in displacing WASP homology domain 2 (WH2) domains of Spire-1 from actin; competitive binding of Fmn2 vs Spire-1 aids actin assembly.

  3. This DNA damage-induced nuclear actin assembly requires two biologically and physically linked nucleation factors: Formin-2 and Spire-1/Spire-2.

  4. The authors propose Spire1C isoform cooperates with INF2 to regulate actin assembly at endoplasmic reticulum-mitochondrial contacts.

  5. Spire recruits Fmn2 and facilitates its association with actin filaments barbed ends.

  6. Spire-1 is specifically recruited at invadosomes and is part of a multi-molecular complex containing Src kinase, the formin mDia1 and actin.

  7. analysis of the molecular basis of the Spir1/formin-2 interaction

  8. The multifunctional character of the WH2 domains allows Spire to sequester four G-actin subunits binding cooperatively in a tight SA(4) complex and to nucleate, sever, and cap filaments at their barbed ends.

  9. both mammalian Spir proteins, Spir-1 and Spir-2, interact with mammalian Fmn subgroup proteins formin-1 and formin-2

Spire Homolog 1 (Drosophila) (SPIRE1) Protein Überblick

Protein Überblick

Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001

Genbezeichner und Symbole assoziert mit SPIRE1

  • spire homolog 1 (Drosophila) (Spire1)
  • spire-type actin nucleation factor 1a (spire1a)
  • spire type actin nucleation factor 1 (SPIRE1)
  • 6030430B19Rik Protein
  • AI415299 Protein
  • AU022898 Protein
  • AW550622 Protein
  • si:ch211-215i13.1 Protein
  • si:zc215i13.1 Protein
  • Spir-1 Protein
  • Spir-2 Protein
  • spire1 Protein
  • zgc:153436 Protein

Bezeichner auf Proteinebene für SPIRE1

protein spire homolog 1 , spire homolog 1 , spire actin nucleation factor 1 , spire family actin nucleation factor 1

GENE ID SPEZIES
68166 Mus musculus
557962 Danio rerio
56907 Homo sapiens
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