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SAMM50 encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. Zusätzlich bieten wir Ihnen Sorting and Assembly Machinery Component 50 Homolog Antikörper (40) und und viele weitere Produktgruppen zu diesem Protein an.
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The authors results demonstrate that SNP in the SAMM50 gene is significantly associated with the presence and severity of NAFLD in a Korean populations.
Findings suggest a significant association between variants in COL13A1, ADIPOQ, SAMM50, and PNPLA3, and risk of NAFLD/elevated transaminase levels in Mexican adults with an admixed ancestry.
Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50.
SAMM50 affects the Drp1-dependent mitochondrial morphology.
downregulation of SAM50 in BCR-ABL-expressing, but not normal CD34(+) human hematopoietic stem and progenitor cells (HSPCs) caused a significant decrease in growth, colony formation, and replating capacity.
the integrity of MICOS and its efficient interaction with Sam50 are indispensable for cristae organization, which is relevant to mitochondrial function.
Polymorphisms in the SAMM50 and PARVB genes in addition to those in the PNPLA3 gene were observed to be associated with the development and progression of NAFLD.
The study describes a novel role of SAM50 in maintaining the mitochondrial shape and the morphology of cristae.
The pathway of Voltage-dependent anion-selective channel biogenesis in human mitochondria involves the TOM complex, Sam50 and metaxins, and that it is evolutionarily conserved.
mitofilin helps regulate mitochondrial morphology and at least four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import
This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane.
sorting and assembly machinery component 50 homolog
, sorting and assembly machinery 50kDa
, transformation-related gene 3 protein
, sorting and assembly machinery component 50 homolog A