anti-Somatostatin Receptor 2 (SSTR2) Antikörper

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. Zusätzlich bieten wir Ihnen Somatostatin Receptor 2 Kits (14) und Somatostatin Receptor 2 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SSTR2 6752 P30874
SSTR2 54305 P30680
SSTR2 20606 P30875
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Top anti-Somatostatin Receptor 2 Antikörper auf antikoerper-online.de

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Ratte Kaninchen Unkonjugiert WB Anti- SSTR2 antibody, Western blotting All lanes: Anti SSTR2  at 0.5ug/ml WB: Rat Lung Tissue Lysate at 50ug Predicted bind size: 41KD Observed bind size: 55KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-SSTR2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human Muscle 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Huhn Kaninchen Unkonjugiert WB Western blot analysis of SSTR2 expression in THP1 (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p) Anti-SSTR2 antibody  ABIN1049362 IHC staining of human brain, subiculum neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-SSTR2 antibody IHC of human brain, subiculum neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p) Anti-SSTR2 antibody  ABIN1049361 IHC staining of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p) Anti-SSTR2 antibody  ABIN1049360 IHC staining of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-SSTR2 antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis of extracts of mouse thymus tissue lysate, using SSTR2 antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277461 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Maus Unkonjugiert CyTOF, FACS, ICC, IHC Detection of Somatostatin R2/SSTR2 in MDA-MB-231 Human Cell Line by Flow Cytometry. MDA-MB-231 human breast cancer cell line was stained with Human Somatostatin R2/SSTR2 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. Somatostatin R2/SSTR2 in MDA-MB-231 Human Cell Line. Somatostatin R2/SSTR2 was detected in immersion fixed MDA-MB-231 human breast cancer cell line using 10 µ 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$302.84
Details

Am meisten referenzierte anti-Somatostatin Receptor 2 Antikörper

  1. Human Polyclonal SSTR2 Primary Antibody für ICC, FACS - ABIN152502 : Reubi, Laissue, Waser, Steffen, Hipkin, Schonbrunn: Immunohistochemical detection of somatostatin sst2a receptors in the lymphatic, smooth muscular, and peripheral nervous systems of the human gastrointestinal tract: facts and artifacts. in The Journal of clinical endocrinology and metabolism 1999 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal SSTR2 Primary Antibody für ELISA, FACS - ABIN4355133 : Agool, Slart, Dierckx, Kluin, Visser, Jager, Vellenga: Somatostatin receptor scintigraphy might be useful for detecting skeleton abnormalities in patients with multiple myeloma and plasmacytoma. in European journal of nuclear medicine and molecular imaging 2009 (PubMed)
    Show all 6 Pubmed References

  3. Human Polyclonal SSTR2 Primary Antibody für IF (p), IHC (p) - ABIN738216 : Sakai, Yonezawa, Yamawaki, Oyamada: Alteration of somatostatin receptor 2 expression in canine mammary gland tumor. in The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2015 (PubMed)
    Show all 2 Pubmed References

  4. Rat (Rattus) Polyclonal SSTR2 Primary Antibody für WB - ABIN3043097 : Guo, Shi, Zhou, Chen: Somatostatin receptors 3, 4 and 5 play important roles in gallbladder cancer. in Asian Pacific journal of cancer prevention : APJCP 2013 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal SSTR2 Primary Antibody für IF, WB - ABIN239101 : Jorand, Biswas, Wakefield, Tobin, Golfetto, Hilton, Ko, Ramos, Small, Chu, Singh, Jovanovic-Talisman: Molecular signatures of mu opioid receptor and somatostatin receptor 2 in pancreatic cancer. in Molecular biology of the cell 2016 (PubMed)

  6. Bat Polyclonal SSTR2 Primary Antibody für WB - ABIN6746609 : Perry, Hustad, Swing, OSullivan, Jenkins, Copeland: The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice. in Nature genetics 1998 (PubMed)

  7. Human Monoclonal SSTR2 Primary Antibody für CyTOF, FACS - ABIN4899106 : Parry, Chen, Andrews, Lears, Rogers: Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2. in Endocrinology 2012 (PubMed)

Weitere Antikörper gegen Somatostatin Receptor 2 Interaktionspartner

Human Somatostatin Receptor 2 (SSTR2) Interaktionspartner

  1. In this cohort showed that most IDH-wild type gliomas did not express SSTR2A protein and a significant overexpression of SSTR2A protein was observed in the IDH-mutant gliomas

  2. Olfactory neuroblastoma demonstrate high SSTR2a expression regardless of their differentiation.

  3. SSTR2 is a poor prognostic biomarker in SCLC and potential future therapeutic signaling target.

  4. SSTR2A expression is correlated with longer OS in medullary thyroid carcinoma, especially for stage IV patients, suggesting that SSTR2A expression might be a useful prognostic factor in medullary thyroid carcinoma.

  5. This study indicates a down-regulation of SSTR2 expression as small intestinal neuroendocrine tumors progress through the intestinal wall, which might signify underlying biological processes of importance for SI-NET invasion behavior.

  6. SSTR2A expression is infrequent in astrocytomas and negative in the majority of glioblastomas where it is of no prognostic significance. In contrast, oligodendrogliomas show intense membranous and cytoplasmic SSTR2A expression.

  7. The results of this study showed the SSTR2 expression was lower in patients pretreated with LA-SSA/PEGV compared to the drug-naive acromegalic patients.

  8. SSTR2 was significantly hypermethylated in colorectal cancer tissues when compared with adjacent normal colorectal tissues.

  9. This study investigated the presence of progenitor/stem cells in non-functioning pituitary tumors (NFPTs) and tested the efficacy of dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists to inhibit in vitro proliferation

  10. expression of MDM2, somatostatin receptor 2A, and PD-L1 in follicular dendritic cell sarcoma

  11. Combination treatment increased both SSTR2 and SSTR5 mRNA and protein levels in DU-145 cells. The data suggest that this combination therapy may be a good candidate for patients with advanced metastatic Prostate cancer (PCa) do not respond to androgen deprivation.

  12. although the limited number of cases with adequate term follow-up, SSTR-2A expression could be a prognostic factor and somatostatin analogs therapeutic candidate for SmCCs of the bladder as these tumors show high percentage of SSTR-2A expression

  13. SSTR2 expression was tested in GH-secreting adenomas from 60 patients with acromegaly who had undergone pituitary surgery, 36 of whom had received octreotide with varying levels of response. Its expression was not correlated with baseline or post-octreotide GH or IGF-1 levels or tumor volume.

  14. Filamin-A is required to mediate SSTR2 effects in pancreatic neuroendocrine tumours

  15. Data showed that the distribution of somatostatin receptor (SSTR) subtypes among the 199 pancreatic neuroendocrine tumors (PNETs) was: SSTR2 (54.8%), SSTR1 (53.3%), SSTR4 (51.8%), SSTR5 (33.7%), and SSTR3 (28.6%).

  16. SSTR2 promoter hypermethylation might be associated with the risk and progression of laryngeal squamous cell carcinoma in males.

  17. VPA was observed to stimulate the expression of somatostatin receptor type 2 (SSTR2).

  18. Results show that histological subtyping of pituitary tumor correlated with SSTR2, E cadherin and p27kip protein levels and these may serve as useful biomarkers for prognosis.

  19. there is an elevation in CXCR4 and a decrease in SSTR2A expression with increasing malignancy in gastroenteropancreatic neuroendocrine neoplasms

  20. mir-185 regulates the expression of SSTR2 in GH-secreting pituitary adenoma. The staining intensity of SSTR2 is stronger in adenoma samples than controls.

Mouse (Murine) Somatostatin Receptor 2 (SSTR2) Interaktionspartner

  1. Unpredictable chronic mild stress (UCMS) caused neuroendocrine changes, physical deteriorations, increased anxiety- and depressive-like behaviors and working memory impairments. sst2KO mice displayed behavioral alterations which were similar to stressed WT and exhibited exacerbated changes following UCMS exposure. The evaluations performed in the older mice showed significant long-term effects of UCMS exposure.

  2. SSTR2 is mainly expressed in distal tubules and collecting ducts in murine kidneys, and the expression of SSTR2 decreases during cyst growth in two polycystic kidney disease mouse models

  3. Both hippocampal sst2 and sst4 receptors selectively inhibit stress-induced HPA axis activation but mediate anxiolytic and antidepressive effects through distinct mechanisms.

  4. Loss of sst2 from pancreatic tissues activates PI3K signaling via AKT, leading to activation of NF-kappaB, amplification of oncogenic KRAS signaling, increased expression of CXCL16, and pancreatic tumor formation.

  5. The expression and localization of the three receptors (SSTR3-SSTR5) in wild-type (WT), single-knockout (SSTR1 KO) and double-knockout SSTR1/SSTR2 (DKO) mice, are reported.

  6. SST2 expression protects against gentamicin-induced auditory hair cell loss in the mammalian inner ear.

  7. Knock-down of SSTR2 leads to loss of pluripotency in murine embryonic stem cells.

  8. Inhibition of the Sstr2 receptor reversed the anticonvulsant effect mediated by cortistatin-14.

  9. OCT-P407 induces mRNA expression of SSTR-2 and caspase-3 and decreases that of VEGF in mice.

  10. The study encourages the use of liver tissue SSR2 protein and mRNA as a reliable tumor marker for liver cancer

  11. when activated by SST-14, SSTR2A internalizes and recycles via the Golgi, which requires ECE-1 degradation of SST-14 and receptor dissociation from beta-arrestins

  12. Findings suggest that somatostatin and its receptors (SSTR2 and SSTR5) are important markers in the regulation and development of Sertoli cell.

  13. The aim of this study was to validate an animal model expressing SSTR2 and to correlate the immunohistochemical (IHC) analysis with (18)F-FDG and (68)Ga-DOTATOC uptake in vivo.

  14. SSTR2 was expressed in Kolliker's organ on E14, on cochlear duct hair cells & supporting cells on E17 and only on the organ of Corti at birth, increasing & peaking at P14 but dropping off at P21.

  15. SSTR2 was well expressed in most of the hypothalamic regions whereas it decreases significantly in ventromedial and arcuate nucleus of ApoD(-/-) mice.

  16. sst2 may protect retinal cells from hypoxia, thus implementing the background to establish potential pharmacological targets.

  17. somatostatin receptors demonstrate specific expression in HCs and supporting cells of the mouse cochlea, and that absence of SST1 alters the expression of SST2.

  18. SSTR2-based reporters can serve as reporters of gene transfer into non-small cell lung cancer.

  19. Overexpressed in endomterium inendometriosis.

  20. sst(2a) and sst(4) were respectively detected in the dentate gyrus (DG) and the CA1 subfield suggesting that their functional interactions are not mediated by direct receptor coupling

Cow (Bovine) Somatostatin Receptor 2 (SSTR2) Interaktionspartner

  1. Follicle-stimulating hormone regulates the SSTR2 protein expression in bovine granulosa cells.

Pig (Porcine) Somatostatin Receptor 2 (SSTR2) Interaktionspartner

  1. SRIF can inhibit testosterone secretion through the sst2A receptor; local inhibitory action of SRIF is probably autocrine & might involve testosterone-induced increase of sst2 receptor expression in immature Leydig cells [SST2A]

  2. is a potent inhibitory receptor displaying a unique set of interrelated dynamic features of agonist-dependent dimerization, dissociation, internalization, and reassociation, a cascade of events that might be critical for receptor function

  3. Data demonstrate that urotensin II and urotensin II-related peptide directly activate somatostatin receptors 2 and 5 and thus mimic the effect of somatostatin on its cognate receptors.

Rhesus Monkey Somatostatin Receptor 2 (SSTR2) Interaktionspartner

  1. Somatostatin directly promoted spontaneous contractions of the circular muscle of macaque intestine via mediation of SSTR2 in myenteric nerve plexus between the longitudinal and the circular muscle.

Guinea Pig Somatostatin Receptor 2 (SSTR2) Interaktionspartner

  1. 5-HT(1A), SST(1), and SST(2) receptors mediate nonadrenergic IPSPs in the noncholinergic (VIP) secretomotor neurons of the submucous plexus of the guinea pig ileum.

Somatostatin Receptor 2 (SSTR2) Antigen-Profil

Protein Überblick

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney.

Genbezeichner und Symbole assoziert mit SSTR2

  • somatostatin receptor 2 (SSTR2) Antikörper
  • somatostatin receptor 2 (Sstr2) Antikörper
  • somatostatin receptor 2 L homeolog (sstr2.L) Antikörper
  • MGC80373 Antikörper
  • Smstr-2 Antikörper
  • Smstr2 Antikörper
  • SS2R Antikörper
  • sst2 Antikörper
  • SSTR-2 Antikörper
  • SSTR2 Antikörper

Bezeichner auf Proteinebene für SSTR2

SRIF-1 , SS2R , somatostatin receptor type 2 , SS-2-R , SS2-R , somatostatin receptor subtype 2 , somatotropin release-inhibiting factor receptor , somatostatin receptor 2 , somatostatin type 2 receptor , somatostatin receptor type 2-like

GENE ID SPEZIES
6752 Homo sapiens
54305 Rattus norvegicus
20606 Mus musculus
282083 Bos taurus
395305 Gallus gallus
403472 Canis lupus familiaris
443137 Ovis aries
443970 Xenopus laevis
454854 Pan troglodytes
497059 Sus scrofa
695526 Macaca mulatta
100455484 Pongo abelii
100605186 Nomascus leucogenys
100723875 Cavia porcellus
100356395 Oryctolagus cuniculus
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