anti-Sodium Channel, Voltage-Gated, Type II, beta (SCN2B) Antikörper

forms a voltage gated sodium channel with alpha subunit\; may modulate sodium channel expression in neurons [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen SCN2B Proteine (10) und SCN2B Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SCN2B 6327 O60939
SCN2B 25349 P54900
SCN2B 72821 Q56A07
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Top anti-SCN2B Antikörper auf antikoerper-online.de

Showing 10 out of 114 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB Western blot analysis of SCN2B expression in HEK293T (A), Raw264.7 (B), rat liver (C) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Maus FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$504.40
Details
Human Maus APC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$513.50
Details
Human Maus PerCP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$513.50
Details
Human Maus Atto 488 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details
Human Maus Atto 565 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details
Human Maus Atto 655 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details
Human Maus Atto 594 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details
Human Maus Atto 680 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details
Human Maus Atto 700 ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Nav beta 2 Monoclonal Antibody, Clone S395-68 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Nav beta 2 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Nav beta 2 Antibody (D) Composite. Western Blot analysis of Rat Brain showing detection of ~40 kDa Nav-Beta-2 protein using Mouse Anti-Nav-Beta-2 Monoclonal Antibody, Clone S395-68 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-Nav-Beta-2 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~40 kDa. 100 μg 3 bis 4 Tage
$514.80
Details

Weitere Antikörper gegen SCN2B Interaktionspartner

Human Sodium Channel, Voltage-Gated, Type II, beta (SCN2B) Interaktionspartner

  1. this study reports the cryo-electron microscopy structures of the human Nav1.7-beta1-beta2 complex bound to two combinations of pore blockers and gating modifier toxins (GMTs), tetrodotoxin with protoxin-II and saxitoxin with huwentoxin-IV, both determined at overall resolutions of 3.2 angstroms.

  2. Findings add to the understanding of beta2 role in Nav 1.5 trafficking and localisation, which must influence cell excitability and electrical coupling in the heart.

  3. The authors identified a flexible loop formed by (72)Cys and (75)Cys, a unique feature among the four beta-subunit isoforms.

  4. Contribution of Cardiac Sodium Channel beta-Subunit Variants to Brugada Syndrome.

  5. In a nonreferred nationwide Danish cohort of SIDS cases, up to 5/66 (7.5%) of SIDS cases can be explained by genetic variants in the sodium channel complex genes.

  6. With increased beta-2 expression, prostate cancer cells display a trend of enhanced association with nerve axons.

  7. sodium channel polymorphisms are associated with epilepsy

  8. SCN2B is a new candidate gene associated with Brugada syndrome.

  9. beta2 is a PS/gamma-secretase substrate, gamma-secretase mediated cleavage of beta2-C-terminal fragment is required for cell-cell adhesion and migration of beta2-expressing cells

Mouse (Murine) Sodium Channel, Voltage-Gated, Type II, beta (SCN2B) Interaktionspartner

  1. Genetic deletion of Scn2b in mice results in ventricular and atrial arrhythmias, consistent with reported SCN2B mutations in human patients.

  2. SCN2B could play an important role in the aging-related cognitive deterioration, which is associated with the regulations of COX5A and FGF-2.

  3. This study demonistrated that scn2b gene expression in mouse dorsal raphe nucleus

  4. beta2 is a PS/gamma-secretase substrate, gamma-secretase mediated cleavage of beta2-C-terminal fragment is required for cell-cell adhesion and migration of beta2-expressing cells

  5. Increased beta2 subunit expression in sensory neurons after nerve injury is functionally significant. Development of mechanical allodynia-like behavior in the SNI model is attenuated in beta2 subunit null mutant mice.

  6. Data suggest that loss of sodium channel beta2 subunit is neuroprotective in experimental allergic encephalomyelitis by prevention of Na+ channel up-regulation in response to demyelination.

SCN2B Antigen-Profil

Protein Überblick

forms a voltage gated sodium channel with alpha subunit\; may modulate sodium channel expression in neurons

Genbezeichner und Symbole assoziert mit SCN2B

  • sodium voltage-gated channel beta subunit 2 (SCN2B) Antikörper
  • sodium voltage-gated channel beta subunit 2 (Scn2b) Antikörper
  • sodium channel, voltage-gated, type II, beta (Scn2b) Antikörper
  • sodium voltage-gated channel beta subunit 2 L homeolog (scn2b.L) Antikörper
  • sodium channel, voltage-gated, type II, beta (scn2b) Antikörper
  • sodium voltage-gated channel beta subunit 2 (scn2b) Antikörper
  • 2810451E09Rik Antikörper
  • AI840361 Antikörper
  • Gm183 Antikörper
  • SCN2B Antikörper
  • SCNB2 Antikörper

Bezeichner auf Proteinebene für SCN2B

neuronal voltage-gated sodium channel beta 2 subunit , sodium channel beta 2 subunit , sodium channel subunit beta-2 , sodium channel, voltage-gated, type II, beta polypeptide , Sodium channel beta 2 , cardiomyocyte sodium channel beta-2 subunit , sodium channel, voltage-gated, type II, beta , sodium voltage-gated channel type II beta , voltage-gated sodium channel beta 2 subunit

GENE ID SPEZIES
6327 Homo sapiens
25349 Rattus norvegicus
72821 Mus musculus
403485 Canis lupus familiaris
419776 Gallus gallus
466796 Pan troglodytes
494804 Xenopus laevis
538722 Bos taurus
678698 Macaca mulatta
777666 Danio rerio
100144663 Xenopus (Silurana) tropicalis
100352300 Oryctolagus cuniculus
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