Sodium Channel, Nonvoltage-Gated 1, delta Proteine (SCNN1D)

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Zusätzlich bieten wir Ihnen Sodium Channel, Nonvoltage-Gated 1, delta Antikörper (77) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus SCNN1D SCNN1D 140501  
SCNN1D 6339 P51172
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage

SCNN1D Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,

Weitere Proteine zu Sodium Channel, Nonvoltage-Gated 1, delta (SCNN1D) Interaktionspartnern

Human Sodium Channel, Nonvoltage-Gated 1, delta (SCNN1D) Interaktionspartner

  1. The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations

  2. deltabetagamma-ENaC is inhibited by CFTR but activated by cyclic AMP.

  3. delta-ENaC expression is low in NCI-H441, Calu-3, and ATI cells and does not contribute to transepithelial sodium absorption

  4. study characterized a new variant, delta2 ENaC, in lung epithelial cells; heterologous delta2betagamma ENaC exhibited a number of divergent features from the delta1betagamma counterpart in biophysics and pharmacology, regulation, and the lifespan of proteins

  5. delta-ENaC undergoes dynamin-independent endocytosis as opposed to alphabetagamma-channels.

  6. These results suggest that COMMD1 downregulates deltaENaC activity by reducing deltaENaC surface expression through promoting internalization of surface deltaENaC to an intracellular recycling pool, possibly via enhanced ubiquitination.

  7. Identify the specific domains of epithelial sodium channels that are responsible for the differences in the response to flow of alphabetagamma and deltabetagamma channels.

  8. Cpt-cAMP activates human epithelial sodium channels via relieving self-inhibition.

  9. CPT-cGMP Stimulates Human Alveolar Fluid Clearance by Releasing External Na+ Self-Inhibition of ENaC.

  10. Data support a physiological role for SGK1.1 in the regulation of delta-ENaC through a pathway that differs from the classical one and suggest that the kinase could serve as an integrator of different signaling pathways converging on the channel.

  11. delta ENaC is regulated by Murr1

  12. ENaCdelta activity is regulated by protons, and may contribute to the pH sensation and/or pH regulation in the human brain

  13. ENaCdelta is chemically activated by capsazepine by a proton-dependent mechanism

  14. the interactions of delta-ENaC with alpha beta gamma-human epithelial sodium channel subunits could account for heterogeneity of native epithelial channels

  15. analysis of anovel spliced variant of the ENaC delta-subunit in the human brain

  16. ENaC delta isoforms are widely expressed in pyramidal cells of the human and monkey cerebral cortex and in different neuronal populations of telencephalic subcortical nuclei.

  17. Expression analyses at the level of mRNA clearly revealed that ENaC delta transcript was strongly expressed in human melanoma cells using reverse transcription-polymerase chain reaction and cell-based in situ hybridization techniques.

  18. EIPA [5-(N-ethyl-N-isopropyl)-amiloride hydrochloride] inhibition of ENaCs, possibly ENaC-alpha and ENaC-delta, significantly improved the sperm motility in healthy donors and in asthenospermia patients.

  19. ENaCdelta is a candidate molecule for pH sensing in the gastrointestinal system in humans, providing a novel therapeutic target for gastro-oesophageal reflux disease

  20. Regulation of epithelial sodium channels by cGMP/PKGII.

Sodium Channel, Nonvoltage-Gated 1, delta (SCNN1D) Protein Überblick

Protein Überblick

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception (By similarity).

Genbezeichner und Symbole assoziert mit SCNN1D

  • sodium channel, nonvoltage-gated 1, delta (Gm20552)
  • sodium channel epithelial 1 delta subunit (SCNN1D)
  • dNaCh Protein
  • ENaCd Protein
  • ENaCdelta Protein
  • SCNED Protein
  • SCNN1D Protein

Bezeichner auf Proteinebene für SCNN1D

sodium channel, nonvoltage-gated 1, delta , amiloride-sensitive sodium channel subunit delta , delta-ENaC , delta-NaCH , epithelial Na(+) channel subunit delta , nonvoltage-gated sodium channel 1 subunit delta , sodium channel, voltage-gated, type I, delta polypeptide , SCNED , epithelial sodium channel delta subunit

140501 Mus musculus
428184 Gallus gallus
489598 Canis lupus familiaris
528813 Bos taurus
6339 Homo sapiens
450189 Pan troglodytes
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