Slingshot Homolog 2 (Drosophila) Proteine (SSH2)

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. Zusätzlich bieten wir Ihnen SSH2 Antikörper (16) und SSH2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SSH2 237860 Q5SW75
SSH2 85464 Q76I76
Ratte SSH2 SSH2 303342  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

SSH2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human ,
,

Weitere Proteine zu Slingshot Homolog 2 (Drosophila) (SSH2) Interaktionspartnern

Mouse (Murine) Slingshot Homolog 2 (Drosophila) (SSH2) Interaktionspartner

  1. A PLCbeta/PI3Kgamma (zeige PIK3CG Proteine)-GSK3 signaling pathway regulates cofilin (zeige CFL1 Proteine) phosphatase slingshot2 and neutrophil polarization and chemotaxis.

Human Slingshot Homolog 2 (Drosophila) (SSH2) Interaktionspartner

  1. Novel signaling pathway consisting of chemoattractant GPCR/Galphai protein, PLC, PKCbeta and PKDs that regulates SSH2/cofilin activity, F-actin polymerization and directional assembly of actin cytoskeleton in neutrophil chemotaxis was identified.

  2. data indicate that: (a) apoptotic cell death in FLCN (zeige FLCN Proteine)-null cells can be triggered by SSH2 knockdown through cell cycle arrest; (b) SSH2 represents a potential therapeutic target for the development of agents for the treatment of BHD (zeige FLCN Proteine) syndrome related tumors

  3. Expression of phosphatase-dead versions of SSH proteins, SSH1 (zeige SSH1 Proteine), SSH2 & SSH3 (zeige SSH3 Proteine) results in phosphorylation/inactivation of cofilin (zeige CFL1 Proteine), changes in cytoskeleton organization, loss of cell polarity, and assembly of aberrant arrays of laminin-332 in keratinocytes.

SSH2 Protein Überblick

Protein Überblick

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1\; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002

Genbezeichner und Symbole assoziert mit SSH2

  • slingshot homolog 2 (Drosophila) (Ssh2)
  • slingshot protein phosphatase 2 (SSH2)
  • slingshot protein phosphatase 2 (Ssh2)
  • slingshot protein phosphatase 2b (ssh2b)
  • BB104748 Protein
  • BC030940 Protein
  • mSSH-2L Protein
  • SSH-2 Protein
  • SSH-2L Protein
  • zgc:175142 Protein

Bezeichner auf Proteinebene für SSH2

SSH-2L , SSH-like protein 2 , protein phosphatase Slingshot homolog 2 , slingshot 2L , slingshot-like 2 , slingshot homolog 2 , slingshot homolog 2b

GENE ID SPEZIES
237860 Mus musculus
85464 Homo sapiens
303342 Rattus norvegicus
557912 Danio rerio
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