Signal Transducing Adaptor Family Member 2 Proteine (STAP2)

STAP2 encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. Zusätzlich bieten wir Ihnen Signal Transducing Adaptor Family Member 2 Antikörper (103) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
STAP2 55620 Q9UGK3
Ratte STAP2 STAP2 363334  
STAP2 106766 Q8R0L1
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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STAP2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Signal Transducing Adaptor Family Member 2 (STAP2) Interaktionspartnern

Human Signal Transducing Adaptor Family Member 2 (STAP2) Interaktionspartner

  1. These findings indicate an essential role for STAP2 in the generation of a high-quality memory CD8+ CTLs periphery, and suggest the therapeutic potential of STAP2 in cancer patients.

  2. High STAP2 expression is associated with prostate cancer.

  3. The Pyk2/STAP-2 interaction is a novel mechanism to regulate SDF-1alpha-dependent T-cell chemotaxis.

  4. STAP2 is upregulated in uterosacral ligaments in pelvic organ prolapse

  5. Our results demonstrate a critical contribution of STAP-2 in BCR-ABL activity.

  6. STAP-2 is a novel participant in the regulation of T cell apoptosis after stimulation

  7. Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.

  8. STAP-2 expression in Jurkat T cells affects migration following stromal cell-derived factor-1alpha (SDF-1alpha) treatment; STAP-2 association with Vav1, the guanine-nucleotide exchanging factor for Rac1, enhances downstream Vav1/Rac1 signaling.

  9. These data indicate that STAP-2/BKS negatively controls the FcepsilonRI-mediated calcium mobilization and degranulation by direct modulation of tyrosine phosphorylation of PLC-gamma.

  10. STAP-2/BKS is a modulator of STAT5-mediated signaling

  11. STAP-2 associates with FAK and enhances its degradation, proteasome inhibitors block FAK degradation, and STAP-2 recruits an endogenous E3 ubiquitin ligase, Cbl, to FAK.

  12. These results suggest that STAP-2 acts as an endogenous negative regulator of Epstein-Barr virus LMP1-mediated signaling through TRAF3 and TRADD.

  13. STAP-2 is phosphorylated at Tyr250 by Brk, and plays an important role in Brk-mediated STAT3 activation.

  14. These results indicate that Cbl regulates STAP-2 protein levels and Brk/STAP-2-mediated STAT3 activation.

Mouse (Murine) Signal Transducing Adaptor Family Member 2 (STAP2) Interaktionspartner

  1. These findings indicate an essential role for STAP2 in the generation of a high-quality memory CD8+ CTLs periphery, and suggest the therapeutic potential of STAP2 in cancer patients.

  2. results demonstrate a contribution of CCR7 to STAP-2-dependent enhancement of BCR-ABL-mediated cell growth in Ba/F3 cells

  3. signal transducing adaptor protein 2 (STAP-2) is involved in cell migration, proliferation, and melanogenesis as well as chemokine receptor expression and tumorigenesis in B16F10 melanoma cells

  4. STAP-2 has a potential to regulate plural molecular events during pathological inflammatory responses.

  5. Signal-transducing adaptor protein-2 controls the IgE-mediated, mast cell-mediated anaphylactic responses.

  6. Our results demonstrate a critical contribution of STAP-2 in BCR-ABL activity.

  7. STAP-2 is a novel participant in the regulation of T cell apoptosis after stimulation

  8. has a crucial role in immune systems by controlling cytokine signal transduction.

  9. STAP-2/BKS is a modulator of STAT5-mediated signaling

  10. STAP-2 directly binds to c-Fms and interferes with the PI3K signaling, which leads to macrophage motility, in Raw 264.7 cells

  11. STAP-2 associates with FAK and enhances its degradation, proteasome inhibitors block FAK degradation, and STAP-2 recruits an endogenous E3 ubiquitin ligase, Cbl, to FAK.

  12. These results suggest that STAP-2 acts as an endogenous negative regulator of Epstein-Barr virus LMP1-mediated signaling through TRAF3 and TRADD.

  13. STAP-2 acts as an endogenous regulator in normal macrophages functions

Signal Transducing Adaptor Family Member 2 (STAP2) Protein Überblick

Protein Überblick

This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit STAP2

  • signal transducing adaptor family member 2 (STAP2)
  • signal transducing adaptor family member 2 (Stap2)
  • signal transducing adaptor family member 2a (stap2a)
  • AW049765 Protein
  • BKS Protein
  • cb901 Protein
  • STAP-2 Protein
  • stap2 Protein
  • wu:fd15d07 Protein
  • zgc:63913 Protein

Bezeichner auf Proteinebene für STAP2

BRK substrate , breast tumor kinase substrate , brk kinase substrate , signal-transducing adaptor protein 2 , signal-transducing adaptor protein-2 , signal transducing adaptor family member 2

GENE ID SPEZIES
55620 Homo sapiens
363334 Rattus norvegicus
505456 Bos taurus
106766 Mus musculus
327172 Danio rerio
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