Sialic Acid Binding Ig-Like Lectin 15 Proteine (SIGLEC15)

Binds sialylated glycoproteins.. Zusätzlich bieten wir Ihnen SIGLEC15 Antikörper (29) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte SIGLEC15 SIGLEC15 498888  
SIGLEC15 284266 Q6ZMC9
Maus SIGLEC15 SIGLEC15 620235  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details

SIGLEC15 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human
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Weitere Proteine zu Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) Interaktionspartnern

Human Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) Interaktionspartner

  1. Siglec-15 recognizes the tumoral sTn (zeige EEF1A2 Proteine) antigen and transduces a signal for enhanced TGF-beta (zeige TGFB1 Proteine) secretion in TAMs

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) Interaktionspartner

  1. Siglec-15 does not mediate joint destruction in inflammatory arthritis

  2. The present findings indicate that Siglec-15 is involved in estrogen deficiency-induced differentiation of osteoclasts and is thus a potential therapeutic target for postmenopausal osteoporosis.

  3. Siglec-15 regulates osteoclast development and bone resorption by modulating receptor activator of nuclear factor kappaB ligand (RANKL (zeige TNFSF11 Proteine)) signaling in association with DAP12 (zeige TYROBP Proteine).

  4. DC-STAMP, Siglec-15, Tspan7 (zeige TSPAN7 Proteine) and Mst1r (zeige MST1R Proteine) expression was downregulated by docosahexaenoic acid, but not eicosapentaenoic acid during osteoclastogenesis in vitro.

  5. results reveal the importance of Siglec-15 in the regulation of osteoclast formation and/or function in vivo, providing new insights into osteoclast biology

  6. the Siglec-15-DAP12 (zeige TYROBP Proteine)-Syk (zeige SYK Proteine)-signaling cascade plays a critical role in functional osteoclast formation.

  7. These results suggest that Siglec-15 plays an important role in osteoclast differentiation.

SIGLEC15 Protein Überblick

Protein Überblick

Binds sialylated glycoproteins.

Genbezeichner und Symbole assoziert mit SIGLEC15

  • sialic acid binding Ig-like lectin 15 (Siglec15)
  • sialic acid binding Ig like lectin 15 (SIGLEC15)
  • Cd33l3 Protein
  • EG620235 Protein
  • HsT1361 Protein
  • RGD1565948 Protein
  • SIGLEC-15 Protein
  • SIGLEC-I Protein

Bezeichner auf Proteinebene für SIGLEC15

sialic acid-binding Ig-like lectin 15 , CD33 antigen-like 3 , CD33 molecule-like 3

GENE ID SPEZIES
498888 Rattus norvegicus
284266 Homo sapiens
620235 Mus musculus
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