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SDR9C7 encodes a protein with similarity to the short-chain dehydrogenase/reductase (SDR) family but has not been shown to have retinoid or dehydrogenase activities.
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Missense mutations in SDR9C7 gene were identified in families with autosomal recessive congenital ichthyosis (zeige LBR Proteine): two families shared an identical homozygous mutation c.599T > C (p.Ile200Thr) and one family had another homozygous mutation c.214C > T (p.Arg72Trp). The mutations severely affected a stability of the protein. In a patient's skin, SDR9C7 gene expression in the cornified layer was decreased.
SDR9C7 promotes esophageal squamous cell carcinoma metastasis partly through regulation of MMP11 (zeige MMP11 Proteine).
short-chain dehydrogenase/reductase (SDR (zeige SDPR Proteine)), retinol dehydrogenase (zeige ADH7 Proteine)-similar (RDH-S), with intense mRNA expression in liver and kidney
This gene encodes a protein with similarity to the short-chain dehydrogenase/reductase (SDR) family but has not been shown to have retinoid or dehydrogenase activities.
, orphan short-chain dehydrogenase / reductase
, orphan short-chain dehydrogenase/reductase
, retinol dehydrogenase similar protein
, short-chain dehydrogenase/reductase family 9C member 7
, short chain dehydrogenase/reductase family 9C, member 7
, short chain dehydrogenase/reductase family 9C member 7
, orphan short chain dehydrogenase/reductase
, retinol dehydrogenase 20