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Binds to plexin family members and plays an important role in the regulation of developmental processes. Zusätzlich bieten wir Ihnen SEMA3C Kits (13) und SEMA3C Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal SEMA3C Primary Antibody für WB - ABIN651266
Esselens, Malapeira, Colomé, Casal, Rodríguez-Manzaneque, Canals, Arribas: The cleavage of semaphorin 3C induced by ADAMTS1 promotes cell migration. in The Journal of biological chemistry 2010
Show all 4 Pubmed References
in situ hybridization analysis revealed that Sema (zeige SEMA3B Antikörper) 3C and Sema (zeige SEMA3B Antikörper) 3F are expressed at the RNA level in the endometriosis affected peritoneum
Androgen receptor (zeige AR Antikörper) transcriptionally regulates semaphorin 3C in a GATA2 (zeige GATA2 Antikörper)-dependent manner in prostate tumor cells.
The exploratory genome-wide association studies confirmed APOE (zeige APOE Antikörper) and identified the novel loci: rs2525776 near SEMA3C (P = 1 x 10(-8), OR = 3.3 [2.1-5.1]).
Aberrant expression of sema3c is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 signaling pathway.
FR-sema3C could perhaps be used for the treatment of AMD (zeige AMD1 Antikörper).
SEMA3C plays a role in the progression of breast cancer and may positively influence breast cancer cell adhesion, invasion and proliferation, as well as being associated with grade of disease and estrogen receptor (zeige ESR1 Antikörper) status.
Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 (zeige NRP2 Antikörper) in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.
Increased levels of Sema3C protein may be associated with the progression of glioma tumor and have potential as a prognostic marker for outcome of glioma patients.
SEMA3C expression increased in the transition from normal to malignant breast lesions and correlated with microvessel density and tumour grade and is differentially regulated in the development of breast versus oral neoplasia.
Glioma stem cells preferentially secrete Sema3C and coordinately express PlexinA2/D1 receptors to activate Rac1/nuclear factor (NF)-kB signaling.
analyzed a complementary set of ligand-specific and tissue-specific mutants to show that neural crest-derived SEMA3C activates NRP1 (zeige NRP1 Antikörper) in the cardiac outflow tract endothelium
Sema3A (zeige SEMA3A Antikörper) overrides the effects of Sema3C in cortical axons exposed to defined mixtures of these opposing guidance cues in vitro
No changes were observed in the binding of Sema3C to Nrp1 (zeige NRP1 Antikörper)-silenced B16(F10 (zeige F10 Antikörper)) cells, nor in its chemorepellent activity.
Data suggest that the formation and synaptic specificity of the GABAergic septohippocampal pathway relies on robust molecular mechanisms, independent of semaphorin 3C.
the guidance factor Semaphorin 3C, which is expressed by corpus callosum neurons, acts through the neuropilin 1 (zeige NRP1 Antikörper) receptor to orient axons crossing through the corpus callosum.
Secreted sema3C favors cell survival and neuritogenesis of cultured cerebellar granule neurons
GATA-6 (zeige GATA6 Antikörper) regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis
sema (zeige SEMA3B Antikörper) 3C promotes glomerular endothelial cell proliferation, adhesion, directional migration, and tube formation in vitro by stimulating integrin phosphorylation and VEGF120 (zeige VEGFA Antikörper) secretion
Npn1 (zeige NRP1 Antikörper)-dependent morphogenesis is mediated by Sema3A (zeige SEMA3A Antikörper) and Sema3C in an additive manner.
The endocytic pathway of neuropilin(Nrp)1 (zeige NRP1 Antikörper) depends on its ligand: sema3C induces lipid raft-dependent endocytosis.
Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).
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