anti-SIX Homeobox 6 (SIX6) Antikörper

The protein encoded by SIX6 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. Zusätzlich bieten wir Ihnen SIX Homeobox 6 Proteine (5) und SIX Homeobox 6 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SIX6 20476 Q9QZ28
SIX6 4990 O95475
SIX6 314221  
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Top anti-SIX Homeobox 6 Antikörper auf antikoerper-online.de

Showing 10 out of 46 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-SIX6 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate Human kidney 100 μL 2 bis 3 Tage
$289.00
Details
Huhn Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of SIX6 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of SIX6 expression in Jurkat (A), NIH3T3 (B) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of SIX6 using anti-SIX6 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human Hela whole cell lysate.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-SIX6 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for SIX6 at approximately 28KD. The expected band size for SIX6 is at 28KD. 100 μg 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from HuvEc/COLO205 cells, using SIX6 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using SIX6 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis on HuvEc cell lysate using SIX6 Antibody,The lane on the left is treated with the antigen-specific peptide. ABIN6266978 staining A-431 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in mouse stomach tissue lysates (35ug/lane). 400 μL 2 bis 3 Tage
$515.63
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 100 μL 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert IF, WB Immunofluorescence analysis of HepG2 cells, using SIX6 polyclonal antibody . Peptide Western blot analysis of extracts from HUVEC cells (Lane 1 and lane 3) and COLO 205 cells (Lane 2), using SIX6 polyclonal antibody . Peptide 100 μg 11 bis 12 Tage
$374.67
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with SIX6 polyclonal antibody . Immunohistochemical staining of human nasopharynx with SIX6 polyclonal antibody  shows strong nuclear positivity in respiratory epithelial cells. 100 μL 11 bis 12 Tage
$577.33
Details

Weitere Antikörper gegen SIX Homeobox 6 Interaktionspartner

Mouse (Murine) SIX Homeobox 6 (SIX6) Interaktionspartner

  1. SIX3 and SIX6 play distinct but compensatory roles in regulating transcription of gonadotrope-specific genes as gonadotrope cells differentiate.

  2. Six6-null mice display abnormal patterns of circadian behavior.

  3. SoxB1 transcription factors are direct activators of Six6 expression in the ventral forebrain

  4. Six6 plays an important role in the regulation of GnRH expression and hypothalamic control of fertility.

  5. in association with Dach corepressors, regulates proliferation of retinal and pituitary precursor cells by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter

  6. Six 3 and Six 6 are differentially required during forebrain development; gene expression in brain

  7. Results show that Lhx2 and Pax6 transcription factors operate in a concerted manner during retinal development to promote transcriptional activation of the Six6 homeobox-gene in primitive and mature retinal progenitors.

Xenopus laevis SIX Homeobox 6 (SIX6) Interaktionspartner

  1. Data show that both six6.L and six6.S expression was restricted to the retina and optic stalk of tailbud embryos.

  2. 2 evolutionary conserved regions 5' and a third 3' to the six6 coding region were identified. The conserved 3' region was necessary and sufficient for eye field and optic vesicle expression. Both conserved enhancer regions located 5' of the coding sequence were required for normal optic cup and mature retinal expression.

Human SIX Homeobox 6 (SIX6) Interaktionspartner

  1. In conclusion, this study confirmed the association between two genome wide association study single nucleotide polymorphisms in SIX6 (rs33912345 and rs10483727) and primary open-angle glaucoma (POAG).

  2. Mutation in SIX6 gene is associated with primary open angle glaucoma.

  3. we confirmed that rs33912345 and rs10483727-the only known cpRNFLT susceptibility SNPs-showed the strongest association with cpRNFLT of those within the SIX1/SIX6 locus.

  4. The results suggest that SIX6 influences different stages of RGC differentiation and their survival; therefore, alteration in SIX6 function due to the risk allele may lead to cellular and molecular abnormalities.

  5. We replicated the association of SNP rs10483727 in the SIX1/SIX6 locus with POAG in a Saudi cohort, suggesting its role in increasing susceptibility to Primary Open Angle Glaucoma .

  6. Among 8 SNPs in 3 loci that showed at least nominal association (P < 5.00E-02) in the primary cohort, a representative SNP for each loci (rs2157719 for CDKN2B-AS1, rs33912345 for SIX6, and rs9913911 for GAS7) were selected

  7. elevated expressions of SIX2, SIX4, and SIX6 predicted poor overall survival (OS) in NSCLC and poor relapse-free survival (RFS) in lung adenocarcinoma

  8. study replicated the association of POAG with two SNPs at the SIX1-SIX6 locus and demonstrated that SNPs, rs10483727 and rs33912345, are significantly associated with POAG, especially with NTG in patients aged above 40 years

  9. Six1 regulates p53 via a dual mechanism involving upregulation of microRNA-27a and downregulation of RPL26.

  10. Single nucleotide polymorphism in SIX6 gene is associated with primary open angle glaucoma.

  11. SIX6 and/or intraocular pressure promotes primary open-angle glaucoma by directly increasing p16INK4a expression.

  12. we report a homozygous missense mutation of SIX6 associated with a unique eye phenotype characterized by optic disc anomalies, macular atrophy, and coloboma of the iris and chorioretina.

  13. Nonglaucomatous individuals with the SIX6 missense variant have reduced RNFL thickness in regions known to be particularly affected in those with glaucoma.

  14. Our results, in combination with previous SIX6 work, lead us to hypothesize that SIX6 risk variants disrupt the development of the neural retina, leading to a reduced number of retinal ganglion cells.

  15. Our findings in humans and zebrafish suggest a functional involvement of six6b in early eye development, and open new insights into the genetic architecture of POAG.

  16. No evidence was found that SIX6 mutations underlie human congenital structural eye malformations.

  17. Six6 and Six2 differ in their DNA-binding mechanisms and in the consequences of their interaction with protein tyrosine phosphatase Eyes Absent in Six2/6-DNA-binding ability.

  18. BOR and OAVS features are associated with duplication of SIX1, SIX6 and OTX2 resulting from a complex chromosomal rearrangement.

Cow (Bovine) SIX Homeobox 6 (SIX6) Interaktionspartner

  1. a new helix in the C-terminal domain of the mutated bovine SIX6 protein was revealed, which possibly affects pituitary development and hormone secretion

SIX Homeobox 6 (SIX6) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).

Genbezeichner und Symbole assoziert mit anti-SIX Homeobox 6 (SIX6) Antikörper

  • sine oculis-related homeobox 6 (Six6) Antikörper
  • SIX homeobox 6a (six6a) Antikörper
  • SIX homeobox 6 L homeolog (six6.L) Antikörper
  • SIX homeobox 6 (SIX6) Antikörper
  • SIX homeobox 6 (Six6) Antikörper
  • MCOPCT2 Antikörper
  • MGC63871 Antikörper
  • OPTX2 Antikörper
  • Six6 Antikörper
  • Six6.1 Antikörper
  • Six6.2 Antikörper
  • Six9 Antikörper
  • XOptx2 Antikörper
  • xSix6 Antikörper
  • zgc:63871 Antikörper

Bezeichner auf Proteinebene für anti-SIX Homeobox 6 (SIX6) Antikörper

homeobox protein SIX6 , optic homeobox 2 , sine oculis homeobox homolog 6 , sine oculis-related homeobox 6 homolog , sine oculis-related homeobox 6a , homeobox protein Optx2 , homeodomain protein OPTX2

GENE ID SPEZIES
20476 Mus musculus
394080 Danio rerio
398128 Xenopus laevis
395843 Gallus gallus
4990 Homo sapiens
490718 Canis lupus familiaris
539749 Bos taurus
314221 Rattus norvegicus
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