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The protein encoded by SEC22B is a member of the SEC22 family of vesicle trafficking proteins. Zusätzlich bieten wir Ihnen SEC22B Antikörper (50) und und viele weitere Produktgruppen zu diesem Protein an.
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this mini review evaluates the role of Sec22b using gene-targeted mice in MHC Class I cross-presentation.
study finds that presentation of the membrane-bound GRA6 Toxoplasma gondii antigen is independent from the SNARE (zeige VTI1B Proteine) Sec22b, a key molecule for transfer of host endoplasmic reticulum components onto the parasitophorous vacuole
required in cross-presentation in dendritic cells to initiate CD8 (zeige CD8A Proteine)+ T cell responses to dead cells and to induce effective antitumor immune responses
Suggest that close apposition of the ER and plasma membrane mediated by Sec22b and plasma membrane syntaxins generates a non-fusogenic SNARE (zeige VTI1B Proteine) bridge contributing to plasma membrane expansion, probably through non-vesicular lipid transfer.
Findings provide insight into an intracellular traffic pathway required for crosspresentation and show that Sec22b-dependent recruitment of endoplasmic reticulum proteins to phagosomes critically influences phagosomal functions in dendritic cells.
The R-SNARE motif, a selective domain for forming a SNARE complex with syntaxin18 and/or D12, was responsible for the inhibition of phagocytosis. Sec22b is a negative regulator of phagocytosis in macrophages by regulating free syntaxin 18 and/or D12.
the target gene SEC22B regulated by miRNA-206 may play a key role in the progression and development of AD.
Suggest that close apposition of the ER and plasma membrane mediated by Sec22b and plasma membrane syntaxins generates a non-fusogenic SNARE (zeige NAPA Proteine) bridge contributing to plasma membrane expansion, probably through non-vesicular lipid transfer.
DrrA activation of the Rab1 GTPase on plasma membrane-derived organelles stimulated the tethering of endoplasmic reticulum-derived vesicles, resulting in vesicle fusion through the pairing of Sec22b with the plasma membrane syntaxin proteins.
The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins.
SEC22 vesicle-trafficking protein homolog B
, SEC22 vesicle-trafficking protein-like 1
, vesicle-trafficking protein SEC22b
, SEC22 vesicle trafficking protein-like 1
, vesicle-trafficking protein SEC22b-a
, ER-Golgi SNARE of 24 kDa