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SATB2 encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. Zusätzlich bieten wir Ihnen SATB2 Antikörper (87) und und viele weitere Produktgruppen zu diesem Protein an.
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Human SATB2 Protein expressed in Wheat germ - ABIN2752928
Nodin, Johannesson, Wangefjord, OConnor, Lindquist, Uhlén, Jirström, Eberhard: Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer. in Diagnostic pathology 2012
SATB2 can be used as a supplementary marker along with CDX2 (zeige CDX2 Proteine) to identify 'colon-rectum' as the primary site in material from patients presenting with metastasis.
We describe the phenotype and genotype of 12 individuals with 10 unique (de novo in 11 of 11 tested) pathogenic variants (1 splice site, 5 frameshift, 3 nonsense, and 2 missense) in SATB2 and review all cases reported in the published literature caused by point alterations thus far
features associated with de novo mutations affecting SATB2 function in individuals ascertained on the basis of intellectual disability
The mRNA level of SATB2 was lower in tumor tissues than in samples of corresponding unchanged kidney. The results of the presented study suggest the tumor-suppressing function of SATB2.
MiR (zeige MLXIP Proteine)-875-5pdirectly binds to the 3'untranslated region of SATB.2
These results strongly suggest that SATB2 prevents induction of EMT (zeige ITK Proteine) by suppressing expression of EMT (zeige ITK Proteine)-inducing transcription factors in NSCLC cells.
We describe here the identification of a de novo SATB2 point mutation in twin boys with cleft soft palate, dental anomalies, and development delay and compare the clinical presentation of SATB2 point mutation patients reported to date.
our data reveal that SATB2 in alveolar bone mesenchymal stem cells (AB-BMSCs) associates with their age-related properties, and prevents AB-BMSCs senescence via maintaining Nanog expression.
SATB2 is frequently expressed in appendiceal mucinous neoplasms. In the context of a mucinous neoplasm involving the ovary, any SATB2 positivity should raise the possibility of appendiceal origin.
our results strongly indicate that the crosstalk between p38 (zeige CRK Proteine) and Akt (zeige AKT1 Proteine) pathways can determine special AT-rich sequence-binding protein 2 expression and epithelial character of non-small-cell lung carcinoma cells
Together, these findings demonstrate that Satb2 is critically involved in long-term plasticity processes in the adult forebrain that underlie the consolidation and stabilization of context-linked memory.
Satb2 is a genetic determinant that mediates proper circuit development in a core sensory-to-motor spinal network.
Data indicate two special AT-rich sequence-binding protein 2 (SATB2) sequence variants in two unrelated patients presenting with Rett-like phenotypes.
results suggest that expression of Sp7 (zeige SP7 Proteine) during the early stage of Satb2-induced osteogenic differentiation of BMSCs is regulated by miR (zeige MLXIP Proteine)-27a.
Data show that Satb2 is required by both callosal projection neurons and subcerebral projection neurons for proper differentiation and axon pathfinding.
Satb2 and Fezf2 (zeige FEZF2 Proteine) regulation promotes subcerebral projection neuron identity in the developing cerebral cortex
Satb2 may also be related to the establishment of species-specific neuropeptide co-phenotypes during postnatal development.
Target genes of miR (zeige MLXIP Proteine)-27a ware significantly up-regulated in Satb2-overexpressing cells.
A comprehensive overview of Satb2 expression in the adult mouse brain.
The Satb2 proteins are dispensable for X chromosome inactivation in mice.
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.
DNA-binding protein SATB2
, special AT-rich sequence-binding protein 2
, special AT-rich sequence binding protein
, SATB homeobox 2
, special AT-rich sequence binding protein 2
, SATB family member 2
, KIAA1034-like DNA binding protein
, two cut domains-containing homeodomain protein