SATB Homeobox 2 Proteine (SATB2)

Human SATB Homeobox 2 (SATB2) Interaktionspartner

1. SATB2 as an additional diagnostic marker for the diagnosis of an ovarian manifestation of low-grade appendiceal mucinous neoplasm

2. HNF4-alpha (zeige HNF4A Proteine) and particularly SATB2 may be helpful in the differential diagnosis of pulmonary adenocarcinoma and metastases of colorectal adenocarcinomas

3. The study identified that decreased expression of SATB2 was correlated with tumor progression and poor prognosis in non-small cell lung cancer (NSCLC) patients. Furthermore, SATB2 suppressed lung cancer cell invasion and metastasis and regulated the expression of EMT (zeige ITK Proteine)-related proteins and histone methylation by G9a (zeige EHMT2 Proteine).

4. this study shows that SATB2 is a diagnostic marker of sinonasal intestinal-type adenocarcinoma

5. SATB2 could serve as a promising diagnostic biomarker of colorectal cancer metastases.

6. SATB2 can be used as a supplementary marker along with CDX2 (zeige CDX2 Proteine) to identify 'colon-rectum' as the primary site in material from patients presenting with metastasis.

7. We describe the phenotype and genotype of 12 individuals with 10 unique (de novo in 11 of 11 tested) pathogenic variants (1 splice site, 5 frameshift, 3 nonsense, and 2 missense) in SATB2 and review all cases reported in the published literature caused by point alterations thus far

8. features associated with de novo mutations affecting SATB2 function in individuals ascertained on the basis of intellectual disability

9. The mRNA level of SATB2 was lower in tumor tissues than in samples of corresponding unchanged kidney. The results of the presented study suggest the tumor-suppressing function of SATB2.

10. MiR (zeige MLXIP Proteine)-875-5pdirectly binds to the 3'untranslated region of SATB.2

Mouse (Murine) SATB Homeobox 2 (SATB2) Interaktionspartner

1. Together, these findings demonstrate that Satb2 is critically involved in long-term plasticity processes in the adult forebrain that underlie the consolidation and stabilization of context-linked memory.

2. Satb2 is a genetic determinant that mediates proper circuit development in a core sensory-to-motor spinal network.

3. Data indicate two special AT-rich sequence-binding protein 2 (SATB2) sequence variants in two unrelated patients presenting with Rett-like phenotypes.

4. results suggest that expression of Sp7 (zeige SP7 Proteine) during the early stage of Satb2-induced osteogenic differentiation of BMSCs is regulated by miR (zeige MLXIP Proteine)-27a.

5. Data show that Satb2 is required by both callosal projection neurons and subcerebral projection neurons for proper differentiation and axon pathfinding.

6. Satb2 and Fezf2 (zeige FEZF2 Proteine) regulation promotes subcerebral projection neuron identity in the developing cerebral cortex

7. Satb2 may also be related to the establishment of species-specific neuropeptide co-phenotypes during postnatal development.

8. Target genes of miR (zeige MLXIP Proteine)-27a ware significantly up-regulated in Satb2-overexpressing cells.

9. A comprehensive overview of Satb2 expression in the adult mouse brain.

10. The Satb2 proteins are dispensable for X chromosome inactivation in mice.