Runt-Related Transcription Factor 3 (RUNX3) ELISA Kits

RUNX3 encodes a member of the runt domain-containing family of transcription factors. Zusätzlich bieten wir Ihnen RUNX3 Antikörper (216) und RUNX3 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
RUNX3 12399  
RUNX3 864 Q13761
RUNX3 156726  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage

Weitere ELISA Kits für RUNX3 Interaktionspartner

Zebrafish Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. In neuronal fate determination, Runx co-factor Cbfbeta is essential for its function, but the high level of Runx3 expression can overcome the loss of Cbfbeta, demonstrating that Cbfbeta in this context serves solely as a signal amplifier of Runx3 activity.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. Runx3 expression leads to an increase in primitive blood cell numbers, together with an increase in runx1 (zeige RUNX1 ELISA Kits)-expressing cells in the ventral wall of the dorsal aorta.

  4. Zebrafish embryos lacking Rad21, or cohesin subunit Smc3, fail to express runx3 and lose hematopoietic runx1 (zeige RUNX1 ELISA Kits) expression in early embryonic development.

Pig (Porcine) Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. These results demonstrate that the CRISPR/Cas9 system is effective in inducing mutations on a specific locus of genome and the RUNX3 knockout pigs can be useful resources for human cancer research and to develop novel cancer therapies.

Mouse (Murine) Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. The findings suggest that the absence of uPA (zeige PLAU ELISA Kits) correlates with increased levels of Runx transcriptional regulators in a way that promotes inflammation-associated carcinogenesis.

  2. Runx3-deficient CD8 (zeige CD8A ELISA Kits)(+) cytotoxic effector T cells aberrantly upregulated genes characteristic of follicular helper T (TFH) cell lineage, including Bcl6 (zeige BCL6 ELISA Kits), Tcf7 (zeige TCF7 ELISA Kits) and Cxcr5 (zeige CXCR5 ELISA Kits). Mechanistically, the Runx3-CBFbeta transcription factor complex deployed H3K27me3 to Bcl6 (zeige BCL6 ELISA Kits) and Tcf7 (zeige TCF7 ELISA Kits) genes to suppress the TFH program.

  3. Deletion of Runx3 in the peripheral nervous system or specifically in peripheral sensory neurons, or of enhancer elements driving Runx3 expression in proprioceptive neurons, induced prepubertal scoliosis.

  4. We found that Runx3 exerted a positive effect on early myeloid development

  5. Runx3 plays a crucial role in the hypothalamo-pituitary-gonadal axis

  6. intricate combinatorial interplay among the three regulatory elements governs Runx3 expression in distinct subtypes of TrkC (zeige NTRK3 ELISA Kits) neurons while concomitantly extinguishing its expression in non-TrkC (zeige NTRK3 ELISA Kits) neurons

  7. this study identifies a compensatory signaling mechanism that prevents lineage-fate errors by dynamically modulating Runx3d induction rates during MHC I positive selection

  8. our data suggest that Runx3 may play a crucial role in the development of DRGs by regulating the expression of Ntrk3 (zeige NTRK3 ELISA Kits) variants

  9. Runx3 is crucial for the phenotypic and functional changes observed in ThPok (zeige ZBTB7B ELISA Kits)-deficient invariant natural killer T cells.

  10. the transcription factor Runx3 was essential for the normal development of subsets of innate lymphoid cells (ILCs) in the mucosa

Human Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. CNRIP1 (zeige Cnrip1 ELISA Kits) and RUNX3 as potential DNA methylation biomarkers for CRC (zeige CALR ELISA Kits) diagnosis and treatment

  2. RUNX3 expression in oral squamous carcinoma cells contributes to their bone invasion and the resulting osteolysis by inducing their malignant behaviors and production of osteolytic factors.

  3. Lower positive expression rate of RUNX3 and higher positive expression rate of Notch1 and Jagged 1 were observed in CRC tissues than those in normal adjacent tissues with a negative correlation, and the expression levels were associated with the differentiation degree, TNM staging, lymph node metastasis and tumor invasion depth (all P<0.05).

  4. Loss of RUNX3 expression strongly correlated with adverse prognosis, independent of subtype. Further studies are warranted to elucidate the biology and prognostic utility of RUNX3 in DLBCL.

  5. Runx3 plays a critical role in R-point regulation and defense against cellular transformation.

  6. RUNX3 mRNA and protein expression were upregulated in nasal-type extranodal NK/T-cell lymphoma (NKTL) patient samples and NKTL cell lines compared to normal NK cells. RUNX3 silenced NKTL cells showed increased apoptosis and reduced cell proliferation. MYC (zeige MYC ELISA Kits) and RUNX3 binding occurs. Potential binding sites for MYC (zeige MYC ELISA Kits) were identified in the RUNX3 enhancer region.

  7. The methylation status of Runx3 gene are abnormal in Hepatocellular Carcinoma patients, which may further be used as molecular markers for early diagnosis of Liver cancer.

  8. RUNX 3 hypermethylation is associated with breast cancer.

  9. High RUNX3 expression is associated with gastric cancer.

  10. we present evidence that RUNX3 can act as a tumor suppressor in a human T-cell malignancy and suggest that this effect is predominantly mediated through transcripts from its distal promoter, in particular RUNX3/p46.

RUNX3 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit RUNX3

  • runt-related transcription factor 3 (runx3) Antikörper
  • runt-related transcription factor 3 (RUNX3) Antikörper
  • runt related transcription factor 3 (RUNX3) Antikörper
  • runt related transcription factor 3 (runx3) Antikörper
  • runt related transcription factor 3 L homeolog (runx3.L) Antikörper
  • runt related transcription factor 3 (Runx3) Antikörper
  • runt-related transcription factor 3 (Runx3) Antikörper
  • AML2 Antikörper
  • Cbfa3 Antikörper
  • frrunx3 Antikörper
  • Pebp2a3 Antikörper
  • PEBP2aC Antikörper
  • runx3 Antikörper
  • runxb Antikörper

Bezeichner auf Proteinebene für RUNX3

runt-related transcription factor b , runt-related transcription factor 3 , core-binding factor 3 , frRunx3/p45 , CBF-alpha-3 , PEA2-alpha C , PEBP2-alpha C , SL3-3 enhancer factor 1 alpha C subunit , SL3/AKV core-binding factor alpha C subunit , acute myeloid leukemia 2 protein , core binding factor alpha 3 , core-binding factor subunit alpha-3 , oncogene AML-2 , polyomavirus enhancer-binding protein 2 alpha C subunit , runt domain, alpha subunit 3 , transcription factor AML2/CBFA3 , PEA2 alpha C , PEBP2 alpha C , acute myeloid leukemia gene 2 , core-binding factor, runt domain, alpha subunit 3 , transcription factor AML2 , Runt related transcription factor 3 , Runx3 MASN-variant

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