Runt-Related Transcription Factor 3 (RUNX3) ELISA Kits

RUNX3 encodes a member of the runt domain-containing family of transcription factors. Zusätzlich bieten wir Ihnen RUNX3 Antikörper (199) und RUNX3 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
RUNX3 12399  
RUNX3 864 Q13761
RUNX3 156726  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage

Weitere ELISA Kits für RUNX3 Interaktionspartner

Zebrafish Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. In neuronal fate determination, Runx co-factor Cbfbeta is essential for its function, but the high level of Runx3 expression can overcome the loss of Cbfbeta, demonstrating that Cbfbeta in this context serves solely as a signal amplifier of Runx3 activity.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. Runx3 expression leads to an increase in primitive blood cell numbers, together with an increase in runx1 (zeige RUNX1 ELISA Kits)-expressing cells in the ventral wall of the dorsal aorta.

  4. Zebrafish embryos lacking Rad21, or cohesin subunit Smc3, fail to express runx3 and lose hematopoietic runx1 (zeige RUNX1 ELISA Kits) expression in early embryonic development.

Pig (Porcine) Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. These results demonstrate that the CRISPR/Cas9 system is effective in inducing mutations on a specific locus of genome and the RUNX3 knockout pigs can be useful resources for human cancer research and to develop novel cancer therapies.

Mouse (Murine) Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. The promoter regions of Runx3 is targets of STAT4 (zeige STAT4 ELISA Kits) and that STAT4 (zeige STAT4 ELISA Kits) binding during NK cell activation induces epigenetic modifications of Runx3 gene loci resulting in increased expression.

  2. Runx3 programs CD8 (zeige CD8A ELISA Kits)(+) T cell residency in non-lymphoid tissues and tumours; results provide insight into the signals that promote T cell residency in non-lymphoid sites, which could be used to enhance vaccine efficacy or adoptive cell therapy treatments that target cancer

  3. Findings suggest that Runx3 may regulate cell shape to inhibit melanoma cell migration partly through enhancing stress fiber formation and ECM (zeige MMRN1 ELISA Kits) protein production.

  4. The findings suggest that the absence of uPA (zeige PLAU ELISA Kits) correlates with increased levels of Runx transcriptional regulators in a way that promotes inflammation-associated carcinogenesis.

  5. Runx3-deficient CD8 (zeige CD8A ELISA Kits)(+) cytotoxic effector T cells aberrantly upregulated genes characteristic of follicular helper T (TFH) cell lineage, including Bcl6 (zeige BCL6 ELISA Kits), Tcf7 (zeige TCF7 ELISA Kits) and Cxcr5 (zeige CXCR5 ELISA Kits). Mechanistically, the Runx3-CBFbeta transcription factor complex deployed H3K27me3 to Bcl6 (zeige BCL6 ELISA Kits) and Tcf7 (zeige TCF7 ELISA Kits) genes to suppress the TFH program.

  6. Deletion of Runx3 in the peripheral nervous system or specifically in peripheral sensory neurons, or of enhancer elements driving Runx3 expression in proprioceptive neurons, induced prepubertal scoliosis.

  7. We found that Runx3 exerted a positive effect on early myeloid development

  8. Runx3 plays a crucial role in the hypothalamo-pituitary-gonadal axis

  9. intricate combinatorial interplay among the three regulatory elements governs Runx3 expression in distinct subtypes of TrkC (zeige NTRK3 ELISA Kits) neurons while concomitantly extinguishing its expression in non-TrkC (zeige NTRK3 ELISA Kits) neurons

  10. this study identifies a compensatory signaling mechanism that prevents lineage-fate errors by dynamically modulating Runx3d induction rates during MHC I positive selection

Human Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. RUNX3 creates an effective barrier against further TGFbeta (zeige TGFB1 ELISA Kits)-dependent tumor progression by preventing genomic instability.

  2. Therefore miR199b may serve as an oncogene (zeige RAB1A ELISA Kits) in Wilms' tumour (WT)progression by directly targeting RUNX3, thereby suggesting that the miR199b/RUNX3 axis may be a promising therapeutic target for patients with WT

  3. High expression of miR (zeige MLXIP ELISA Kits)-20a-5p significantly decreased both the mRNA and protein levels of RUNX3, as well as its direct downstream targets Bim (zeige BCL2L11 ELISA Kits) and p21 (zeige CDKN1A ELISA Kits).

  4. The present results suggested that methylation may serve a critical role in the silencing of RUNX3 and loss of RUNX3 expression may serve as a prognostic marker in endometrial cancer.

  5. RUNX3 expression correlates with tumor's differentiation, depth of invasion, lymph node metastasis, distant metastasis, TNM stage and overall survival of gastric cancer patients.

  6. MiR (zeige MLXIP ELISA Kits)-182/HOXA9 was involved in the process of RUNX3-mediated GC tumor growth.

  7. The BMP9 (zeige GDF2 ELISA Kits)-induced phosphorylation of Smad1 (zeige GARS ELISA Kits)/5/8 was increased with the overexpression of RUNX3, and yet was decreased with the knockdown of RUNX3. Collectively, our findings suggest that RUNX3 is an essential modulator of the BMP9 (zeige GDF2 ELISA Kits)-induced osteoblast lineage differentiation of mesenchymal stem cells (MSCs).

  8. results suggest that EZH2 (zeige EZH2 ELISA Kits) regulates cell proliferation potentially by targeting RUNX3 through the Wnt (zeige WNT2 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits) signaling pathway in laryngeal carcinoma.

  9. These findings suggested that RUNX3 played a tumor suppressor role in oral squamous cell carcinoma (OSCC) by inhibiting cell migration, invasion and angiogenesis, supporting that it could be a potential therapeutic target for OSCC

  10. Study showed that Runx3 was found a target of miR-106b, and the inhibition of miR-106b upregulated Runx3. These results provide evidence that Runx3 is a tumor-suppressor in retinoblastoma and is a target of miR-106b.

RUNX3 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit RUNX3

  • runt-related transcription factor 3 (runx3) Antikörper
  • runt-related transcription factor 3 (RUNX3) Antikörper
  • runt related transcription factor 3 (RUNX3) Antikörper
  • runt related transcription factor 3 (runx3) Antikörper
  • runt related transcription factor 3 L homeolog (runx3.L) Antikörper
  • runt related transcription factor 3 (Runx3) Antikörper
  • runt-related transcription factor 3 (Runx3) Antikörper
  • AML2 Antikörper
  • Cbfa3 Antikörper
  • frrunx3 Antikörper
  • Pebp2a3 Antikörper
  • PEBP2aC Antikörper
  • runx3 Antikörper
  • runxb Antikörper

Bezeichner auf Proteinebene für RUNX3

runt-related transcription factor b , runt-related transcription factor 3 , core-binding factor 3 , frRunx3/p45 , CBF-alpha-3 , PEA2-alpha C , PEBP2-alpha C , SL3-3 enhancer factor 1 alpha C subunit , SL3/AKV core-binding factor alpha C subunit , acute myeloid leukemia 2 protein , core binding factor alpha 3 , core-binding factor subunit alpha-3 , oncogene AML-2 , polyomavirus enhancer-binding protein 2 alpha C subunit , runt domain, alpha subunit 3 , transcription factor AML2/CBFA3 , PEA2 alpha C , PEBP2 alpha C , acute myeloid leukemia gene 2 , core-binding factor, runt domain, alpha subunit 3 , transcription factor AML2 , Runt related transcription factor 3 , Runx3 MASN-variant

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