Ring Finger Protein 115 Proteine (RNF115)

Acts as an E2-dependent E3 ubiquitin-protein ligase. Zusätzlich bieten wir Ihnen RNF115 Antikörper (39) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RNF115 27246 Q9Y4L5
RNF115 67845 Q9D0C1
Ratte RNF115 RNF115 362002  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage

RNF115 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
Mouse (Murine)

Weitere Proteine zu Ring Finger Protein 115 (RNF115) Interaktionspartnern

Human Ring Finger Protein 115 (RNF115) Interaktionspartner

  1. Specifically, BCA2 serves as an E3 SUMO ligase in the SUMOylation of IkappaBalpha (zeige NFKBIA Proteine), which in turn enhances the sequestration of NF-kappaB (zeige NFKB1 Proteine) components in the cytoplasm. Since HIV-1 utilizes NF-kappaB (zeige NFKB1 Proteine) to promote proviral transcription, the BCA2-mediated inhibition of NF-kappaB (zeige NFKB1 Proteine) significantly decreases the transcriptional activity of HIV-1.

  2. BCA2 functions as an antiviral factor that targets HIV-1 Gag for degradation, impairing virus assembly and release.

  3. BCA2 is an endogenous inhibitor of AMPK (zeige PRKAA1 Proteine) activation in breast cancer cells and BCA2 inhibition increases the efficacy of metformin.

  4. BCA2, a potential oncogenic E3 ubiquitin ligase (zeige MUL1 Proteine), promotes breast cancer cell proliferation partially through targeting p21 (zeige CDKN1A Proteine) for ubiquitination and proteasomal degradation.

  5. RNF126 and Rabring7 play a role in the ubiquitin-dependent sorting and downregulation of membrane receptors.

  6. High BCA2 expression is associated with renal oncocytoma.

  7. BCA2 is therefore a newly identified transcriptional target of estrogen receptor (zeige ESR1 Proteine).

  8. Rabring7 stimulates c-Myc (zeige MYC Proteine) degradation via mono-ubiquitination of MM-1 (zeige PFDN5 Proteine)

  9. BCA2 accelerates the internalization and degradation of viral particles following their tethering to the cell surface and is a co-factor or enhancer for the tetherin (zeige BST2 Proteine)-dependent restriction of HIV-1 release from infected cells.

  10. BCA2 E3 ligase is coregulated with estrogen receptor (zeige ESR1 Proteine) and plays a role in the regulation of epidermal growth factor receptor (EGF-R (zeige EGFR Proteine)) trafficking

Mouse (Murine) Ring Finger Protein 115 (RNF115) Interaktionspartner

  1. Rabring7 plays crucial roles as a Rab7 (zeige RAB7A Proteine) target protein in vesicle traffic to late endosome/lysosome and lysosome biogenesis (rabring7)

RNF115 Protein Überblick

Protein Überblick

Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking.

Genbezeichner und Symbole assoziert mit RNF115

  • ring finger protein 115 (RNF115)
  • ring finger protein 115 (Rnf115)
  • 2610028E05Rik Protein
  • AU042696 Protein
  • BCA2 Protein
  • Zfp364 Protein
  • ZNF364 Protein

Bezeichner auf Proteinebene für RNF115

E3 ubiquitin-protein ligase RNF115 , rabring 7 , zinc finger protein 364 , Rab7-interacting RING finger protein , Rabring7 , RING finger protein 115 , Rabring 7

27246 Homo sapiens
612818 Canis lupus familiaris
67845 Mus musculus
362002 Rattus norvegicus
614061 Bos taurus
Ausgewählte Anbieter für RNF115 Proteine (RNF115)
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