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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Zusätzlich bieten wir Ihnen Ribosomal Protein L11 Antikörper (91) und und viele weitere Produktgruppen zu diesem Protein an.
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PICT-1 is a major nucleolar sensor of the DNA damage repair response and an important upstream regulator of p53 (zeige TP53 Proteine) via the RPL11-MDM2 (zeige MDM2 Proteine)-p53 (zeige TP53 Proteine) pathway.
A novel pathogenic mutation in RPL11 identified in a patient diagnosed with diamond Blackfan anemia as a young adult.
RPL splicing variant is associated with Diamond-Blackfan anemia.
Simulation of HEY1 (zeige HEY1 Proteine) Ser (zeige SIGLEC1 Proteine)-68 phosphorylation prevents its interaction with p53 (zeige TP53 Proteine), RPL11 and MDM2 (zeige MDM2 Proteine) and abolishes HEY1 (zeige HEY1 Proteine) migration to nucleolar caps (zeige CAPS Proteine) upon ribosomal stress. Our findings uncover a novel mechanism for cross-talk between Notch (zeige NOTCH1 Proteine) signalling and nucleolar stress
Data suggest 5S ribosomal RNA is a direct target of miR (zeige MLXIP Proteine)-150 and miR (zeige MLXIP Proteine)-383 in esophageal squamous cell carcinoma (ESCC); overexpression of miR (zeige MLXIP Proteine)-150 and miR (zeige MLXIP Proteine)-383 inhibits ESCC cell proliferation in vitro and in vivo and intensifies RPL11/c-Myc (zeige MYC Proteine) interaction.
Ribosomal proteins L11 and L5 activate TAp73 (zeige TP73 Proteine) by overcoming MDM2 (zeige MDM2 Proteine) inhibition.
Data indicate that ribosomal protein (L11) promotes the recruitment of microRNA-130a (miR (zeige MLXIP Proteine)-130a) to oncoprotein c-Myc (zeige MYC Proteine) in response to UV irradiation treatment.
Data indicate that ribosomal protein L11 (RPL11)-expressing cells proliferated more rapidly than the ribosomal protein L11 (RPL11)-expressing cells.
Findings uncover a mechanism by which RPL5 (zeige RPL5 Proteine) and RPL11 can co-operatively suppress c-Myc (zeige MYC Proteine) expression, allowing a tightly controlled ribosome biogenesis in cells.
levels of branched-chain aminotransferase-1 (BCAT1 (zeige BCAT1 Proteine)) transcripts are significantly decreased on the polysomes of both RPS19 (zeige RPS19 Proteine) and RPL11 cells and that translation of BCAT1 (zeige BCAT1 Proteine) protein is especially impaired in cells with small RP gene mutations
there is a fine tuned balance in the interaction of ribosomal proteins with the MDM2 (zeige MDM2 Proteine)/p53 (zeige TP53 Proteine) axis which is important in normal hematopoiesis.
The association of the L11 and Mdm2 (zeige MDM2 Proteine) is resulted the activation of the pathway in embryonic stem cells.
ribosomal dysfunction due to the loss of L11 activates a p53 (zeige TP53 Proteine)-dependent checkpoint response to prevent improper embryonic development.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
60S ribosomal protein L11
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, ribosomal protein L11
, ribosomal protein DL11
, ribosomal protein L11 L homeolog