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RNASE7 is a member of the RNase A superfamily that has broad-spectrum antimicrobial activity and ribonuclease activity (Harder and Schroder, 2002 [PubMed 12244054]\\\\; Zhang et al., 2003 [PubMed 12527768]).[supplied by OMIM, Dec 2008].. Zusätzlich bieten wir Ihnen RNASE7 Antikörper (19) und RNASE7 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.
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These data suggest that the induction of RNase 7 in response to Mycobacterium tuberculosis could have a role in anti-mycobacterial immunity.
RNase 7 has immunomodulatory functions on TH2 cells and decreases the production of TH2 cytokines in the skin.
Our results indicate that RNase 7 is an important factor released by keratinocytes to control the growth of P. aeruginosa on the skin surface.
Insulin (zeige INS Proteine) and PI3K (zeige PIK3CA Proteine)/AKT (zeige AKT1 Proteine) signaling are essential for RNase 7 expression and increased infection risks in diabetic patients may be secondary to suppressed RNase 7 production.
This article provides an overview about the role of RNase 7 in cutaneous defense with focus on the molecular mechanism of the antimicrobial activity of RNase 7, the regulation of RNase 7 expression, and the role of RNase 7 in skin diseases. [review]
RNH1 (zeige RNH1 Proteine) bound to RNase 7 and suppressed its antimicrobial activity by blocking its ability to bind the cell wall of uropathogenic bacteria.
epidermal growth factor (zeige EGF Proteine)-dependent RNase 7 and human beta-defensin-3 (zeige DEFB103A Proteine) expression upon infection with Trichophytum rubrum
RNase 7 is an antimicrobial protein that plays an important role in the innate immune defense system of human epithelia.
Suggest that RNase 7 may function as antimicrobial peptide (zeige CAMP Proteine) with a role in the differentiation and development of the primitive epidermis.
Levels of psoriasin (zeige S100A7 Proteine), RNase 7 and hBD-3 (zeige DEFB103A Proteine) expression - assessed by immunohistochemistry - varied between different body localisations.
RNASE7 is a member of the RNase A superfamily that has broad-spectrum antimicrobial activity and ribonuclease activity (Harder and Schroder, 2002
, ribonuclease 7
, skin-derived antimicrobial protein 2