Protein Überblick

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation (By similarity).

Genbezeichner und Symbole assoziert mit RPRD1B

• regulation of nuclear pre-mRNA domain containing 1B (rprd1b) Antikörper
• regulation of nuclear pre-mRNA domain containing 1B L homeolog (rprd1b.L) Antikörper
• regulation of nuclear pre-mRNA domain containing 1B (RPRD1B) Antikörper
• regulation of nuclear pre-mRNA domain containing 1B (Rprd1b) Antikörper

• 2610304G08Rik Antikörper
• 2810446G03Rik Antikörper
• C13H20ORF77 Antikörper
• C20orf77 Antikörper
• Crept Antikörper
• Alle Synonyme
• dJ1057B20.2 Antikörper
• fb23h08 Antikörper
• MGC130705 Antikörper
• NET60 Antikörper
• RGD1304782 Antikörper
• rprd1ba Antikörper
• wu:fb23h08 Antikörper
• zgc:55687 Antikörper

Bezeichner auf Proteinebene für RPRD1B

regulation of nuclear pre-mRNA domain-containing protein 1B , unm hi3400 , un-named hi3400 , regulation of nuclear pre-mRNA domain containing 1B , regulation of nuclear pre-mRNA domain containing 1B a , Regulation of nuclear pre-mRNA domain containing 1B , cell cycle-related and expression-elevated protein in tumor , cell-cycle related and expression-elevated protein in tumor