Regucalcin (RGN) ELISA Kits

The protein encoded by RGN is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. Zusätzlich bieten wir Ihnen Regucalcin Antikörper (67) und Regucalcin Proteine (20) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
RGN 19733 Q64374
RGN 9104 Q15493
RGN 25106 Q03336
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Top Regucalcin ELISA Kits auf

Showing 7 out of 16 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Human 0.109 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 bis 16 Tage
Ratte 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests 15 bis 18 Tage
Human < 0.109 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests 11 bis 18 Tage
  96 Tests 11 bis 18 Tage
Rind (Kuh)
  96 Tests 15 bis 18 Tage
  96 Tests 15 bis 18 Tage
  96 Tests 15 bis 18 Tage

Weitere ELISA Kits für Regucalcin Interaktionspartner

Zebrafish Regucalcin (RGN) Interaktionspartner

  1. SMP30/RGN is important for liver proliferation and tumorigenesis.

Mouse (Murine) Regucalcin (RGN) Interaktionspartner

  1. In SMP30 deficient mice, colitis was significantly exacerbated as demonstrated by increased mortality (p=0.001), body weight loss (p=0.0105 at day 8), rectal bleeding (p=0.0047 at day 8) and diarrhea (p=0.0030 at day 8), histological scores (ulcers, p=0.0002; edema, p=0.0125; leukocyte infiltration, p=0.0016) and productions of pro-inflammatory cytokines (IL-1alpha, p=0.0452; IL-6, p=0.0074; G-CSF).

  2. It was confirmed that hair growth was significantly promoted; hair growth from hair papilla cells was also confirmed by HE staining of the shaved backs of SMP-30/GNL-KO mice in the vitamin C(+) group

  3. The phosphorylated eNOS and Akt levels and VEGF levels in ischemic muscle were lower in SMP30 KO and old mice than in young mice. Deficiency of SMP30 exacerbates oxidative stress related to NADPH oxidase activity enhancement and impairs eNOS activity, which leads to rarefaction of angiogenesis induced by ischemia

  4. Results suggested that SMP30 deficiency augments myocardial Ischemia/Reperfusion injury through reactive oxygen species generation and attenuation of Akt activation.

  5. This is the first report that stem cell replacement increased the expression of SMP30 in the liver, and may help prevent fibrosis in the liver of db/db mice.

  6. SMP30/GNL-positive cells localized around the central veins of livers of mice and decreased numerically with aging. Nuclear SMP30/GNL protein might be a regulatory factor specific for genes whose expression governs transcription and the aging process.

  7. SMP30 may be a potent inhibitory protein against oxidative stress and chronic inflammation.

  8. SMP30 plays an important role in the regulation of coronary vascular tone by myocardium.

  9. These results suggested that SMP30 might be involved in overriding the apoptotic homeostatic mechanism in response to DNA damage.

  10. SMP30 deficiency is closely associated with non-alcoholic fatty liver disease pathogenesis.

  11. left ventricular ejection fraction was more severely reduced in the DOX-treated SMP30 KO mice than in the DOX-treated WT mice, but was preserved in the DOX-treated SMP30 TG mice

  12. Results from using this unique model of AA deficiency, the SMP30/GNL-KO mouse, now provide new information about formerly unknown AA functions that will implement further study of AA in vivo.

  13. SMP30/gluconolactonase mRNA transcripts were detected in the ovaries of mice, and the expression of these transcripts increased from days 0 to 8 of gestation and decreased rapidly thereafter.

  14. Administration of ACh into the aortic sinus in vivo of SMP30 KO mice induced coronary artery spasm.

  15. evidence that deficiency of SMP30 exacerbates Ang II-induced cardiac hypertrophy, dysfunction, and remodelling, suggesting that SMP30 has a cardio-protective role in cardiac remodelling with anti-oxidative and anti-apoptotic effects in response to Ang II

  16. Cardiac-specific overexpression of SMP30 inhibits angiotensin II-induced cardiac adverse remodeling

  17. Morphological analysis revealed that neonates of SMP30/GNL KO mothers whose intake of AA was low during gestation manifested abnormal cardiac dilation, congestion of liver and lungs, incompletely expanded pulmonary alveoli, and impaired vertebral bodies

  18. The present study shows that modulation of astrocytic SMP30 can be a promising target for treating PD.

  19. structural feature of mouse SMP30/GNL seems to facilitate the gamma-lactone-ring formation.

  20. Differences in amino acid residues in the binding pocket dictate substrate specificity of mouse SMP-30.

Human Regucalcin (RGN) Interaktionspartner

  1. In vitro experiments on colonic epithelial cells showed that stable SMP30 expression inhibited but that SMP30 siRNA expression increased TNF-alpha-induced apoptosis. SMP30 inhibition decreased Nrf2 mRNA expression levels (p<0.0001), but SMP30 overexpression increased Nrf2 mRNA expression levels (p=0.0495).

  2. SMP-30 overexpression plays a protective role in UVB-induced apoptosis via regulating the expression of apoptosis-related proteins and inhibiting the production of ROS in HLE-B3 cells

  3. Data obtained demonstrated that the prolonged survival of patients with renal cell carcinoma (RCC) was associated with a higher regucalcin gene expression, and that the diminished regucalcin gene expression was accompanied by the poor prognosis of patients with RCC. Further findings suggest that regucalcin plays a suppressive role in the promotion of human RCC.

  4. Study suggests that regucalcin plays a crucial role as a suppressor in human colorectal cancer, and that the suppressed expression of the regucalcin gene may predispose patients to the promotion of colorectal cancer.

  5. The SMP30 may serve as a candidate of HCC clinical prognostic marker.

  6. Dat show that regucalcin (RGN) is lowly expressed in hepatocellular carcinoma (HCC) tissues and down-regulates the proliferation ability of HepG2 cells.

  7. These findings suggest that regucalcin may play a potential role as a suppressor of human lung cancer, and that downregulation of regucalcin expression may predispose patients to development of lung cancer.

  8. The role of RGN suppressing cell proliferation is associated with the regulation of expression of oncogenes and tumor suppressor genes. [review]

  9. High RGN expression is associated with hepatocellular carcinoma.

  10. the present study suggests that regucalcin may have important anticancer properties in human breast cancer patients. Mechanistically, these effects are likely mediated through suppression of multiple signaling pathways, upregulation of p53 and downregulation of oncogenes leading to anti-proliferative effects and reduced metastases to bone, a phenotype associated with poor clinical outcome.

  11. Study demonstrates that increased regucalcin gene expression greatly contributes to prolonged survival in human pancreatic cancer patients. Morover, overexpression of regucalcin was found to suppress the proliferation, which is enhanced through various signaling pathways.

  12. Study results suggest that senescence marker protein-30 and senescence-associated beta-galactosidase expressions in both nuclear cataract and cortical cataract patients were associated with lens epithelial cells apoptosis.

  13. data suggest that exogenous regucalcin exerts suppressive effects on the proliferation of human pancreatic cancer cells.

  14. immunohistochemistry revealed a significant decrease of regucalcin in human kidney disease tissue vs control kidney tissue, and regucalcin was detected in exosomes isolated from healthy donors' urine but not from kidney disease patients

  15. results highlighted the importance of RGN as a regulatory protein in Ca2+-dependent signaling pathways and its deregulation of RGN expression by Ca2+o may contribute for onset and progression of PCa.

  16. This review will discuss regarding to an involvement of regucalcin as a suppressor protein in human carcinogenesis in insight into the gene therapy. [review]

  17. The alternatively spliced variants of the regucalcin gene were found to be expressed in various human normal and tumor tissues.

  18. RGN overexpression protected from carcinogen-induced mammary gland tumor development and was linked with reduced proliferation and increased apoptosis. These findings indicated the protective role of RGN in the carcinogenesis of mammary gland.

  19. SMP30 can inhibit the proliferation and invasion of human hepatoma cells and thus can be regarded as a cancer suppressive factor.

  20. Overexpression of prostate RGN transgene in the prostate inhibits cell proliferation and apoptotic pathways.

Cow (Bovine) Regucalcin (RGN) Interaktionspartner

  1. estrogen administration down-regulated RGN gene expression in the accessory sex glands of veal calves and beef cattle, while androgen treatment reduced RGN gene expression only in the testis.

Regucalcin (RGN) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein.

Genbezeichner und Symbole assoziert mit Regucalcin (RGN) ELISA Kits

  • CG1803 gene product from transcript CG1803-RA (regucalcin) Antikörper
  • regucalcin (rgn) Antikörper
  • regucalcin (LOC465598) Antikörper
  • regucalcin (RGN) Antikörper
  • GE16489 gene product from transcript GE16489-RB (Dyak\regucalcin) Antikörper
  • regucalcin (senescence marker protein-30) (RGN) Antikörper
  • regucalcin (Rgn) Antikörper
  • regucalcin L homeolog (rgn.L) Antikörper
  • AI265316 Antikörper
  • CG1803 Antikörper
  • Dmel\\CG1803 Antikörper
  • DyakGE16489 Antikörper
  • dyak_GLEANR_17905 Antikörper
  • GE16489 Antikörper
  • GNL Antikörper
  • Rc Antikörper
  • Reguc Antikörper
  • regucalcin Antikörper
  • rgn-A Antikörper
  • SMP-30 Antikörper
  • SMP30 Antikörper
  • T1 Antikörper
  • xsmp-30 Antikörper
  • xsmp30 Antikörper
  • zgc:92078 Antikörper

Bezeichner auf Proteinebene für Regucalcin (RGN) ELISA Kits

CG1803-PA , CG1803-PB , CG1803-PC , CG1803-PD , regucalcin-PA , regucalcin-PB , regucalcin-PC , regucalcin-PD , RC , gluconolactonase , regucalcin , regucalcin (senescence marker protein-30) , DyakGE16489-PA , Dyakregucalcin-PA , GE16489-PA , SMP-30 , senescence marker protein 30 , senescence marker protein-30 , xSMP-30

32165 Drosophila melanogaster
403070 Danio rerio
448549 Xenopus (Silurana) tropicalis
465598 Pan troglodytes
480893 Canis lupus familiaris
6523987 Drosophila yakuba
100060684 Equus caballus
100171395 Ovis aries
100174578 Pongo abelii
100196365 Salmo salar
100528098 Ictalurus punctatus
19733 Mus musculus
9104 Homo sapiens
395480 Gallus gallus
373659 Xenopus laevis
25106 Rattus norvegicus
768107 Sus scrofa
280910 Bos taurus
100008619 Oryctolagus cuniculus
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