Regenerating Islet-Derived 2 Proteine (REG2)

Might act as an inhibitor of spontaneous calcium carbonate precipitation.. Zusätzlich bieten wir Ihnen Regenerating Islet-Derived 2 Antikörper (16) und Regenerating Islet-Derived 2 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
REG2 19693 Q08731
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
Human Cells Maus His tag   50 μg Anmelden zum Anzeigen 4 Days
Human Cells Maus His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage

REG2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Weitere Proteine zu Regenerating Islet-Derived 2 (REG2) Interaktionspartnern

Mouse (Murine) Regenerating Islet-Derived 2 (REG2) Interaktionspartner

  1. Normal expression of Reg2 gene is required for appropriate compensations in pancreatic islet proliferation and expansion in response to obesity and aging.

  2. mReg2 inhibits AIF-mediated apoptosis by promoting the nuclear presence of Scythe and inducing hsp70.

  3. Reg2 induces glucose-regulated peptide 78 (GRP78) expression via the Akt-mTORC1 axis.

  4. Direct stimulation of Reg2 and Reg3beta genes by glucocorticoids.

  5. Reg2, Reg3alpha, and Reg3beta were abundantly expressed in most acinar cells of the pancreas with clear age-dependent and isoform-specific patterns.

  6. Reg2 protects MIN6 cells from streptozotocin-induced apoptosis by attenuating streptozotocin's ability to disrupt mitochondrial membrane integrity, activate caspase-3 and promote poly-ADP ribose polymerase cleavage, and induce apoptosis.

  7. adjuvant immunotherapy regulates type 1 diabetes in diabetic mice and induces Reg2-mediated regeneration of beta cells

  8. Overexpression of Reg2 gene offered no protection against streptozotocin-induced beta-cell damage and diabetes and did not protect acinar cells against caerulein-induced acute pancreatitis.

  9. Reg2 deficiency enhanced liver sensitivity to Fas-induced oxidative stress and delayed liver regeneration with persistent TNF-alpha/IL6/STAT3 signaling.

  10. RegII is a novel beta-cell-derived autoantigen in NOD mice. The autoimmune response against this protein may convert a regenerative into an islet-destructive process accelerating development of type 1 diabetes. [regII protein]

  11. Reg-II is a likely mouse exocrine pancreas cytoprotective candidate protein whose expression is regulated by keratin filament organization and phosphorylation

Regenerating Islet-Derived 2 (REG2) Protein Überblick

Protein Überblick

Might act as an inhibitor of spontaneous calcium carbonate precipitation.

Genbezeichner und Symbole assoziert mit REG2

  • regenerating islet-derived 2 (Reg2)
  • RegII Protein

Bezeichner auf Proteinebene für REG2

PSP , PTP , REG-2 , islet of Langerhans regenerating protein 2 , lithostathine-2 , pancreatic stone protein 2 , pancreatic thread protein 2 , regenerating islet-derived, mouse homolog 2

19693 Mus musculus
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