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Might act as an inhibitor of spontaneous calcium carbonate precipitation.. Zusätzlich bieten wir Ihnen Regenerating Islet-Derived 2 Antikörper (16) und und viele weitere Produktgruppen zu diesem Protein an.
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Normal expression of Reg2 gene is required for appropriate compensations in pancreatic islet proliferation and expansion in response to obesity and aging.
mReg2 inhibits AIF-mediated apoptosis by promoting the nuclear presence of Scythe and inducing hsp70.
Reg2 induces glucose-regulated peptide 78 (GRP78) expression via the Akt-mTORC1 axis.
Direct stimulation of Reg2 and Reg3beta genes by glucocorticoids.
Reg2, Reg3alpha, and Reg3beta were abundantly expressed in most acinar cells of the pancreas with clear age-dependent and isoform-specific patterns.
Reg2 protects MIN6 cells from streptozotocin-induced apoptosis by attenuating streptozotocin's ability to disrupt mitochondrial membrane integrity, activate caspase-3 and promote poly-ADP ribose polymerase cleavage, and induce apoptosis.
adjuvant immunotherapy regulates type 1 diabetes in diabetic mice and induces Reg2-mediated regeneration of beta cells
Overexpression of Reg2 gene offered no protection against streptozotocin-induced beta-cell damage and diabetes and did not protect acinar cells against caerulein-induced acute pancreatitis.
Reg2 deficiency enhanced liver sensitivity to Fas-induced oxidative stress and delayed liver regeneration with persistent TNF-alpha/IL6/STAT3 signaling.
RegII is a novel beta-cell-derived autoantigen in NOD mice. The autoimmune response against this protein may convert a regenerative into an islet-destructive process accelerating development of type 1 diabetes. [regII protein]
Reg-II is a likely mouse exocrine pancreas cytoprotective candidate protein whose expression is regulated by keratin filament organization and phosphorylation
Might act as an inhibitor of spontaneous calcium carbonate precipitation.
, islet of Langerhans regenerating protein 2
, pancreatic stone protein 2
, pancreatic thread protein 2
, regenerating islet-derived, mouse homolog 2