Regenerating Islet-Derived 1 alpha Proteine (REG1A)

REG1A is a type I subclass member of the Reg gene family. Zusätzlich bieten wir Ihnen Regenerating Islet-Derived 1 alpha Antikörper (93) und Regenerating Islet-Derived 1 alpha Kits (53) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
REG1A 24714 P10758
REG1A 5967 P05451
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Top Regenerating Islet-Derived 1 alpha Proteine auf

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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Human Cells Ratte Fc Tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
Human Cells Human His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
Human Cells Cynomolgus Fc Tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
Human Cells Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

REG1A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Rat (Rattus) , ,
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Human , , , ,
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Weitere Proteine zu Regenerating Islet-Derived 1 alpha (REG1A) Interaktionspartnern

Human Regenerating Islet-Derived 1 alpha (REG1A) Interaktionspartner

  1. Serum levels of PCT and PSP are promising biomarkers for early diagnosis of pediatric acute osteomyelitis.

  2. PSP/reg levels are significantly up-regulated in diabetic kidney disease patients and might be related to renal injury

  3. Both univariate and multivariate analysis demonstrated that REG1A expression was associated with OS and PFS, and conducted harmful effects on nasopharyngeal carcinoma progression and survival. This study suggested that REG1A expression could serve as an independent adverse factor for survival in nasopharyngeal carcinoma.

  4. Reg I may play a role in the maintenance of mucosal barrier function by inducing tight junction proteins such as claudins 3 and 4.

  5. the prognostic value of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), and pancreatic stone protein (PSP) in children with sepsis, was investigated.

  6. REG1alpha was overexpressed in bladder cancer tissues compared with adjacent normal samples. Downregulation of REG1alpha expression in urothelial bladder cancer can reduce tumor growth, migration, invasion and angiogenesis.

  7. REG-I is expressed in head and neck squamous cell carcinoma and is associated with a longer survival status.

  8. We have established a novel, three-protein biomarker panel that is able to detect patients with early-stage pancreatic cancer in urine specimens:LYVE-1, REG1A, and TFF1 were selected as candidate biomarkers

  9. post-operative serum PSP levels were significantly associated with the presence of infection in both the on-pump and off-pump setting.

  10. REG Ialpha protein may play a role in angiogenesis during progression of gastric cancer

  11. PSP/reg is significantly up-regulated in T2DM patients, and PSP/reg levels are related to the duration of diabetes.

  12. the expression of REG Ialpha and REG Ibeta may be upregulated in human beta cells under inflammatory conditions through the JAK/STAT pathway

  13. Collectively, these findings suggest that REG Ialpha activates c-Jun via the JNK and ERK pathway, thereby enhancing radiosensitivity

  14. Pancreactic stone protein levels were able to diagnose sepsis in patients admitted to intensive care units.

  15. PSP/reg levels were significantly higher in patients with a PELOD score of 12 or higher or in those with multiple organ dysfunction syndrome. Patients who died tended to have higher PSP/reg levels.

  16. REG Ialpha overexpression is a characteristic ofsessile serrated adenoma/polyps of the colon, which appears to reflect aberration of crypt cell compartmentalization.

  17. The effects of REG IA on AD and SCC cells were different in the in vitro study, and a correlation between REG IA expression and patient prognosis was noted in the in vivo study

  18. Reduced REG1A expression is associated with chemosensitivity in advanced thoracic esophageal squamous cell carcinoma.

  19. PSP/reg and CRP are differentially regulated by HNF1A and HNF4A in maturity-onset diabetes of the young

  20. Immunohistochemistry against known cell-type markers on serial sections has localised the expression of REGs to metaplastic Paneth cells (REG1A, REG1B and REG3A) and enteroendocrine cells (REG4), with a marked expansion of expression during inflammation.

Regenerating Islet-Derived 1 alpha (REG1A) Protein Überblick

Protein Überblick

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

Genbezeichner und Symbole assoziert mit REG1A

  • regenerating family member 1 alpha (Reg1a)
  • regenerating family member 1 alpha (REG1A)
  • regenerating islet-derived 1 alpha (REG1A)
  • ICRF Protein
  • LITHOST Protein
  • P19 Protein
  • PSP Protein
  • PSPS Protein
  • PSPS1 Protein
  • PTP Protein
  • RATLITHOST Protein
  • RATRGPI Protein
  • REG Protein
  • Reg1 Protein
  • Rgp1 Protein
  • RGPI Protein

Bezeichner auf Proteinebene für REG1A

ICRF , PSP , PTP , islet cells regeneration factor , islet of Langerhans regenerating protein , lithostathine , pancreatic stone protein , pancreatic thread protein , regenerating islet-derived mouse homolog 1 , regeneration protein, lithostatin, pancreatic stone protein , REG-1-alpha , islet of langerhans regenerating protein , lithostathine 1 alpha , lithostathine-1-alpha , pancreatic stone protein, secretory , protein-X , regenerating islet-derived protein 1-alpha , regenerating protein I alpha , regenerating islet-derived 1 alpha , regenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic thread protein)

24714 Rattus norvegicus
5967 Homo sapiens
711892 Macaca mulatta
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