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The protein encoded by RECQL is a member of the RecQ DNA helicase family.
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The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.
ATP-dependent DNA helicase Q1
, RecQ protein-like (DNA helicase Q1-like)
, ATP-dependent DNA helicase Q1-like
, DNA-dependent ATPase Q1
, recQ protein-like 1
, DNA helicase, RecQ-like type 1