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The protein encoded by RBCK1 is similar to mouse UIP28/UbcM4 interacting protein. Zusätzlich bieten wir Ihnen RBCK1 Proteine (5) und RBCK1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 80 products:
Human Polyclonal RBCK1 Primary Antibody für IHC, IHC (p) - ABIN4349528
Fiil, Damgaard, Wagner, Keusekotten, Fritsch, Bekker-Jensen, Mailand, Choudhary, Komander, Gyrd-Hansen: OTULIN restricts Met1-linked ubiquitination to control innate immune signaling. in Molecular cell 2013
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Human Polyclonal RBCK1 Primary Antibody für WB - ABIN1881731
Gustafsson, Zhao, Gustafsson, Dahlman-Wright: RBCK1 drives breast cancer cell proliferation by promoting transcription of estrogen receptor alpha and cyclin B1. in Cancer research 2010
Show all 3 Pubmed References
LUBAC components control TLR3 (zeige TLR3 Antikörper)-mediated innate immunity, thereby preventing development of immunodeficiency and autoinflammation.
results unveil HOIL1 as a negative regulator of lymphocyte activation cleaved by MALT1 (zeige MALT1 Antikörper).
HOXA1 (zeige HOXA1 Antikörper)-mediated activation of NF-kappaB (zeige NFKB1 Antikörper) is non-transcriptional and the RBCK1 and TRAF2 (zeige TRAF2 Antikörper) influences on NF-kappaB (zeige NFKB1 Antikörper) are epistatic to HOXA1 (zeige HOXA1 Antikörper)
Late in the NF-kappaB (zeige NFKB1 Antikörper) activation cycle HOIL1 cleavage transiently reduces linear ubiquitination, including of NEMO (zeige IKBKG Antikörper) and RIP1 (zeige UQCRFS1 Antikörper), dampening NF-kappaB (zeige NFKB1 Antikörper) activation and preventing reactivation.
human HOIP (zeige RNF31 Antikörper) is essential for the assembly and function of LUBAC, which includes HOIL-1, and for various processes governing inflammation and immunity in both hematopoietic and nonhematopoietic cells
findings support a role for RBCK1 in the regulation of FKBPL (zeige FKBPL Antikörper) with important implications for estrogen receptor (zeige ESR1 Antikörper) signaling, cell proliferation and response to endocrine therapy.
RBCK1 deficiency is a frequent cause of polyglucosan storage myopathy associated with progressive muscle weakness and cardiomyopathy.
Suggest that RBCK1 is important for the ubiquitination of PXR (zeige NR1I2 Antikörper) and may play a role in its proteasomal degradation.
Estrogen receptor-alpha (zeige ESR1 Antikörper), RBCK1, and protein kinase C beta 1 (zeige PRKCB Antikörper) cooperate to regulate estrogen receptor-alpha (zeige ESR1 Antikörper) gene expression.
Patients from two kindreds of a new fatal inherited disorder characterized by chronic autoinflammation, invasive bacterial infections and muscular amylopectinosis carried biallelic loss-of-expression and loss-of-function mutations in HOIL1.
Study found that the NZF domain of SHARPIN, but not that of HOIL-1L, is critical for effective protection from programmed cell death by enhancing the recruitment of the linear ubiquitin chain assembly complex to the activated TNFR complex. HOIL-1l seems to be missing the K63-linked ubiquitin chains binding activity which appears to be involved in the recruitment.
Late in the NF-kappaB (zeige NFKB1 Antikörper) activation cycle HOIL1 cleavage transiently reduces linear ubiquitination, including of NEMO (zeige IKBKG Antikörper) and RIP1 (zeige RALBP1 Antikörper), dampening NF-kappaB (zeige NFKB1 Antikörper) activation and preventing reactivation.
These data provide first evidence of a mechanism of cancer cell adaptation to hypoxia where HIFs regulate HOIL-1L, which targets PKCzeta (zeige PRKCZ Antikörper) for degradation to promote tumor survival.
analysis of recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
results demonstrate a powerful approach for the identification of signaling molecules associated with cell surface receptors and indicate an important role for the ubiquitin ligase (zeige RNF123 Antikörper) activity of HOIP (zeige RNF31 Antikörper) in proximal CD40 (zeige CD40 Antikörper) signaling
The protein encoded by this gene is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms.
RanBP-type and C3HC4-type zinc finger containing 1
, ranBP-type and C3HC4-type zinc finger-containing protein 1-like
, HBV associated factor 4
, HBV-associated factor 4
, RBCC protein interacting with PKC1
, RING finger protein 54
, heme-oxidized IRP2 ubiquitin ligase 1
, hepatitis B virus X-associated protein 4
, ranBP-type and C3HC4-type zinc finger-containing protein 1
, ubiquitin conjugating enzyme 7 interacting protein 3
, ubiquitin-conjugating enzyme 7-interacting protein 3
, heme-oxidized IRP2 ubiquitin ligase 1 homolog
, novel zinc finger, C3HC4 type (RING finger) protein
, ubcM4-interacting protein 28
, RBCC protein interacting with PKC 1
, protein kinase C-binding protein Beta15
, protein kinase C-binding protein beta-15