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RNPS1 encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. Zusätzlich bieten wir Ihnen RNPS1 Antikörper (15) und RNPS1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.
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ubiquitin-specific protease 4 (USP4) is a binding partner of RNPS1.
SRBD1 gene polymorphism is associated with the development of HTG as well as NTG, including late-onset NTG.
The phosphorylation of RNPS1 at Ser-53 influences the efficiencies of both splicing and translation.
RNPS1 is able to function together with ASF/SF2 to form ribonucleoprotein complexes on nascent transcripts, and thereby prevent formation of transcriptional R-loops.
has a role in mRNA surveillance (detecting mRNAs with truncated open reading frames and subjecting them to nonsense-mediated mRNA decay (NMD))
binds to Upf complexes which bind upstream of mRNA exon-exon junctions
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene\; both variants encode the same protein.
RNA-binding protein with serine-rich domain 1
, RNA-binding protein S1, serine-rich domain
, SR protein
, SR-related protein LDC2