anti-RIKEN cDNA 4930404A10 Gene Antikörper
Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase- mediated cleavage.
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anti-RIKEN cDNA 4930404A10 Gene (4930404A10RIK) (AA 18-91) Antikörper Primary Antibody
anti-RIKEN cDNA 4930404A10 Gene (4930404A10RIK) (AA 18-91) Antikörper (HRP) Primary Antibody
anti-RIKEN cDNA 4930404A10 Gene (4930404A10RIK) (AA 18-91) Antikörper (FITC) Primary Antibody
anti-RIKEN cDNA 4930404A10 Gene (4930404A10RIK) (AA 18-91) Antikörper (Biotin) Primary Antibody
RIKEN cDNA 4930404A10 Gene (4930404A10RIK) Antigen-Profil
Protein Überblick
Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase- mediated cleavage. Acts by facilitating kinetochore mono- orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis. {ECO:0000269|PubMed:25533956}.
Genbezeichner und Symbole assoziert mit 4930404A10RIK
- meiotic kinetochore factor (Meikin) Antikörper
- 4930404A10Rik Antikörper
Bezeichner auf Proteinebene für 4930404A10RIK
meiosis-specific kinetochore protein
| GENE ID | SPEZIES |
|---|---|
| 74847 | Mus musculus |
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