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The protein encoded by RELT is a member of the TNF-receptor superfamily. Zusätzlich bieten wir Ihnen RELT Antikörper (105) und RELT Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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Findings suggest that RELT acts as a negative regulator that controls the early phase of T-cell activation probably by promoting T-cell apoptosis.
Collectively, this study provides more insights into RELT expression, RELT family member function, and the mechanism of RELT-induced death.
report that overexpression of RELT or its homologues RELL1 and RELL2 in HEK 293 epithelial cells results in cell death with morphological characteristics consistent with the activation of an apoptotic pathway.
Receptor expressed in lymphoid tissue (RELT) and its novel homologues RELL1 and RELL2 co-localize with one another at the plasma membrane.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
tumor necrosis factor receptor superfamily member 19L
, receptor expressed in lymphoid tissues