Pseudouridylate Synthase 1 Proteine (PUS1)

PUS1 encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. Zusätzlich bieten wir Ihnen Pseudouridylate Synthase 1 Antikörper (47) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus PUS1 PUS1 56361 Q9WU56
PUS1 80324 Q9Y606
Ratte PUS1 PUS1 304567 Q4KM92
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
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PUS1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu Pseudouridylate Synthase 1 (PUS1) Interaktionspartnern

Mouse (Murine) Pseudouridylate Synthase 1 (PUS1) Interaktionspartner

  1. Results identify a pseudouridine synthase, mPus1p, as a coactivator for retinoic acid receptor (zeige RARA Proteine) (mRAR)gamma when coexpressed with steroid receptor (zeige ESR2 Proteine) RNA activator.

  2. Pus1p- and Pus3p-dependent pseudouridylation of SRA (zeige MSR1 Proteine) controls a coactivator-corepressor switch in SRA (zeige MSR1 Proteine) with major consequences for NR signaling.

Human Pseudouridylate Synthase 1 (PUS1) Interaktionspartner

  1. results show that the NTD of ERalpha (zeige ESR1 Proteine) and AR contains a novel RBM (zeige RBMY1A1 Proteine) that directly binds SRA (zeige SRA1 Proteine), and that STR5 can serve as a novel class of RNA inhibitor of ERalpha (zeige ESR1 Proteine) and AR signaling by interfering with Pus1p-mediated SRA (zeige SRA1 Proteine) pseudouridylation

  2. We identified one novel homozygous null mutation in a familial case. It predicts a nonsense mutation at glutamine 154 (Q154X) that would lead to a protein lacking the 266 C-terminal amino acids

  3. Missense mutation in pseudouridine synthase 1 causes mitochondrial myopathy and sideroblastic anemia

Pseudouridylate Synthase 1 (PUS1) Protein Überblick

Protein Überblick

This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit PUS1

  • pseudouridylate synthase 1 (PUS1)
  • pseudouridylate synthase 1 (PVX_093530)
  • pseudouridylate synthase 1, putative (PKH_011400)
  • pseudouridine synthase 1 (Pus1)
  • pseudouridylate synthase 1 (Pus1)
  • A730013B20Rik Protein
  • MLASA1 Protein
  • MPUS1 Protein
  • mPus1p Protein
  • PUS1 Protein

Bezeichner auf Proteinebene für PUS1

pseudouridylate synthase 1 , tRNA pseudouridine synthase A, mitochondrial , tRNA pseudouridine(38-40) synthase , tRNA pseudouridylate synthase I , tRNA-uridine isomerase I , mitochondrial tRNA pseudouridine synthase A , tRNA uridine isomerase I , pseudouridine synthase 1

GENE ID SPEZIES
515808 Bos taurus
5471495 Plasmodium vivax Sal-1
7318494 Plasmodium knowlesi strain H
56361 Mus musculus
80324 Homo sapiens
304567 Rattus norvegicus
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