Pseudouridylate Synthase 1 Proteine (PUS1)

PUS1 encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. Zusätzlich bieten wir Ihnen Pseudouridylate Synthase 1 Antikörper (53) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus PUS1 PUS1 56361 Q9WU56
PUS1 80324 Q9Y606
Ratte PUS1 PUS1 304567 Q4KM92
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen

Top Pseudouridylate Synthase 1 Proteine auf

Showing 3 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human PUS1 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage

PUS1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu Pseudouridylate Synthase 1 (PUS1) Interaktionspartnern

Mouse (Murine) Pseudouridylate Synthase 1 (PUS1) Interaktionspartner

  1. Collectively, these results suggest that alterations in muscle metabolism related to mitochondrial content and oxidative capacity may account for the reduced exercise capacity in Pus1(-/-) mice.

  2. Results identify a pseudouridine synthase, mPus1p, as a coactivator for retinoic acid receptor (mRAR)gamma when coexpressed with steroid receptor RNA activator.

  3. Pus1p- and Pus3p-dependent pseudouridylation of SRA controls a coactivator-corepressor switch in SRA with major consequences for NR signaling.

Human Pseudouridylate Synthase 1 (PUS1) Interaktionspartner

  1. results show that the NTD of ERalpha and AR contains a novel RBM that directly binds SRA, and that STR5 can serve as a novel class of RNA inhibitor of ERalpha and AR signaling by interfering with Pus1p-mediated SRA pseudouridylation

  2. Investigation of the sequence and structural requirements for hPus1p activity on human tRNASer.

  3. We identified one novel homozygous null mutation in a familial case. It predicts a nonsense mutation at glutamine 154 (Q154X) that would lead to a protein lacking the 266 C-terminal amino acids

  4. Missense mutation in pseudouridine synthase 1 causes mitochondrial myopathy and sideroblastic anemia

  5. MLASA is associated with absent or greatly reduced tRNA pseudouridylation at specific sites, implicating this pathway in its molecular pathogenesis.

  6. A new homozygous stop mutation (E220X)predicts a protein missing 208/427 amino acid residues on the C terminus. The nuclear isoform has an N-terminal extension absent in the mature mitochondrial isoform.

  7. Three residues (R116, Y173, R267) that correspond to amino acids known to compose the active site of TruA, a bacterial Psi synthase that is homologous to Pus1p, were mutated in human Pus1p.

Pseudouridylate Synthase 1 (PUS1) Protein Überblick

Protein Überblick

This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit PUS1

  • pseudouridylate synthase 1 (PUS1)
  • pseudouridylate synthase 1 (PVX_093530)
  • pseudouridylate synthase 1, putative (PKH_011400)
  • pseudouridine synthase 1 (Pus1)
  • pseudouridylate synthase 1 (Pus1)
  • A730013B20Rik Protein
  • MLASA1 Protein
  • MPUS1 Protein
  • mPus1p Protein
  • PUS1 Protein

Bezeichner auf Proteinebene für PUS1

pseudouridylate synthase 1 , tRNA pseudouridine synthase A, mitochondrial , tRNA pseudouridine(38-40) synthase , tRNA pseudouridylate synthase I , tRNA-uridine isomerase I , mitochondrial tRNA pseudouridine synthase A , tRNA uridine isomerase I , pseudouridine synthase 1

515808 Bos taurus
5471495 Plasmodium vivax Sal-1
7318494 Plasmodium knowlesi strain H
56361 Mus musculus
80324 Homo sapiens
304567 Rattus norvegicus
Ausgewählte Anbieter für Pseudouridylate Synthase 1 Proteine (PUS1)
Haben Sie etwas anderes gesucht?