anti-Proteolipid Protein 1 (PLP1) Antikörper

PLP1 encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. Zusätzlich bieten wir Ihnen Proteolipid Protein 1 Kits (21) und Proteolipid Protein 1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PLP1 5354 P60201
PLP1 24943 P60203
PLP1 18823 P60202
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Top anti-Proteolipid Protein 1 Antikörper auf antikoerper-online.de

Showing 10 out of 48 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PLP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Hela cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-PLP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5µg/ml using anti-PLP1 antibody (ARP33843_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Maus Unkonjugiert FACS, IHC (fro), IF, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$544.50
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert IP, WB PLP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLP1 expression in mouse testis. PLP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLP1 expression in A-431. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details
Maus Kaninchen Unkonjugiert ICC, WB Western Blot: Myelin PLP Antibody [ABIN2615973] - Analysis of adult mouse brain samples. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Huhn Unkonjugiert ICC, IF, IHC (p), IHC, WB In this tissue section through an e 13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei. 0.25 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Rind (Kuh) Maus Unkonjugiert IHC (fro), IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with PLP1 antibody ABIN364261 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PLP1 antibody ABIN364261 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB Anti-PLP1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959011 concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details
Human Maus Unkonjugiert ICC, IHC (fro), IHC (p), WB Anti-PLP1 antibody IHC staining of human brain cerebellum, neuropil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103681 dilution 10 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details

PLP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
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Mouse (Murine) , ,
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Am meisten referenzierte anti-Proteolipid Protein 1 Antikörper

  1. Cow (Bovine) Monoclonal PLP1 Primary Antibody für IHC (fro), FACS - ABIN2475779 : Ballard: Retrospective studies of left atrial thrombus: does misclassification impair their clinical utility? in Journal of general internal medicine 1991 (PubMed)
    Show all 4 Pubmed References

  2. Mouse (Murine) Polyclonal PLP1 Primary Antibody für ICC, WB - ABIN261597 : Horiuchi, Maezawa, Itoh, Wakayama, Jin, Itoh, Decarli: Amyloid β1-42 oligomer inhibits myelin sheet formation in vitro. in Neurobiology of aging 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal PLP1 Primary Antibody für ICC, IF - ABIN151155 : Cachón-González, Wang, Ziegler, Cheng, Cox: Reversibility of neuropathology in Tay-Sachs-related diseases. in Human molecular genetics 2014 (PubMed)

Weitere Antikörper gegen Proteolipid Protein 1 Interaktionspartner

Human Proteolipid Protein 1 (PLP1) Interaktionspartner

  1. Authors investigated the disease progression in mouse models carrying PLP1 point mutations previously found in patients displaying clinical features of multiple sclerosis. These mouse models show loss-of-function of PLP1 associated with neuroinflammation.

  2. Review focusing on sequences in hPLP1 intron 1 DNA deemed important for hPLP1 gene activity as well as a couple of "human-specific" supplementary exons within the first intron which are utilized to generate novel splice variants, and the potential role that these sequences may play in PLP1-linked disorders.

  3. it seems that the epitopes of some microorganisms mimicking PLP such as PLP58-74 might have a potential role in the initiation of Multiple Sclerosis.

  4. Human induced pluripotent stem cells-derived oligodendrocytes from 12 individuals with Pelizaeus-Merzbacher and identified individual and shared defects in PLP1 mRNA expression and splicing, oligodendrocyte progenitor development, and oligodendrocyte morphology and capacity for myelination.

  5. report a novel mutation of the PLP1 gene in two siblings with Pelizaeus-Merzbacher disease associated with a rare and protean neuroimaging finding of optic nerve enlargement

  6. Identification and functional study of novel PLP1 mutations in Chinese patients with Pelizaeus-Merzbacher disease. We identified PLP1 mutations in seven male patients with PMD.

  7. In major depressive disorder there was a significantly reduced expression of PLP1 mRNA.

  8. Study investigated 17 unrelated Pelizaeus-Merzbacher disease subjects with copy number gains at the PLP1 locus including triplication and quadruplication of specific genomic intervals-16/17 were found to have a duplication-inverted triplication-duplication rearrangement product.

  9. Myelin proteolipid protein is critical to regulating oligodendrocyte progenitor cell migration.

  10. PLP1 splicing mutations may result in a wide variety of disease phenotypes through a combination of multiple molecular pathogenic mechanisms.

Mouse (Murine) Proteolipid Protein 1 (PLP1) Interaktionspartner

  1. The rumpshaker missense mutation in the Plp1 gene gives rise to subcortical myoclonus

  2. axonal mitochondria, smooth endoplasmic reticulum, and microtubules were characterized in rodent optic nerves where PLP (zeige C3 Antikörper) is replaced by the peripheral nerve myelin protein, P0.

  3. The observations collectively support the idea that GST-pi (zeige GSTP1 Antikörper)(Nuc (zeige SREBF2 Antikörper))/DM-20 mRNA-expressing cells are the progeny of NG2 (zeige Vcan Antikörper)-positive OPCs rather than a novel type of oligodendrocyte-lineage progenitor cells and that DM-20 mRNA expression is dynamically regulated during differentiation of OPCs into oligodendrocytes.

  4. In the absence of P0, thus, PLP (zeige C3 Antikörper) also contributes to myelination by Schwann cells and to the preservation of peripheral axons

  5. while PLP (zeige C3 Antikörper) can co-exist with P0 in peripheral nervous system(PNS) myelin, PLP (zeige C3 Antikörper) cannot replace P0 as the major structural protein of PNS myelin.

  6. Both extracellular and intracellular epitopes of PLP (zeige C3 Antikörper) contribute to the pathogenesis of MP4-induced experimental autoimmune encephalomyelitis already in the setting of intact myelin.

  7. The insertion of native PLP (zeige C3 Antikörper) into Olg mitochondria of animals with PLP1/Plp1 regulates extracellular pH and adenosine triphosphate.

  8. This study shows for the first time that Plp (zeige C3 Antikörper)-null mice exhibit severe early-onset thermal hyperalgesia that is not associated with changes in thermal allodynic behavior.

  9. A novel mechanism sheds light on the immune regulation by which sulfatide-reactive type II natural killer (NK)T cells suppress inflammatory class II histocompatibility-restricted pathogenic CD4 (zeige CD4 Antikörper)+ T cell responses in a T cell-mediated autoimmune disease.

  10. that an early reactive glia response occurs following mutations in the PLP (zeige C3 Antikörper) gene

Proteolipid Protein 1 (PLP1) Antigen-Profil

Protein Überblick

This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.

Genbezeichner und Symbole assoziert mit PLP1

  • proteolipid protein 1 (PLP1) Antikörper
  • proteolipid protein 1 (Plp1) Antikörper
  • proteolipid protein 1 (plp1) Antikörper
  • proteolipid protein (myelin) 1 (Plp1) Antikörper
  • myelin proteolipid protein (Tsp_11640) Antikörper
  • myelin proteolipid protein (plp) Antikörper
  • proteolipid protein 1 L homeolog (plp1.L) Antikörper
  • proteolipid protein 1a (plp1a) Antikörper
  • DKFZp459O081 Antikörper
  • DKFZp459O113 Antikörper
  • DM20 Antikörper
  • DMalpha2c Antikörper
  • GPM6C Antikörper
  • hld1 Antikörper
  • jimpy Antikörper
  • jp Antikörper
  • mmpl Antikörper
  • msd Antikörper
  • plp Antikörper
  • PLP/DM20 Antikörper
  • plp1 Antikörper
  • plp1a Antikörper
  • pmd Antikörper
  • rsh Antikörper
  • spg2 Antikörper
  • wu:fc27f01 Antikörper
  • wu:fj36d03 Antikörper
  • wu:fj42d08 Antikörper
  • zgc:110499 Antikörper

Bezeichner auf Proteinebene für PLP1

lipophilin , major myelin proteolipid protein , myelin proteolipid protein , Proteolipid protein (Pelizaeus-Merzbacher disease spastic paraplegia 2 uncomplicated) , Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) , proteolipid protein (myelin) 1 , proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) , proteolipid protein, lipophilin , proteolipid protein 1 , myelin synthesis deficiency , rump shaker , PLP , PLP-A , lipophilin-A , myelin proteolipid protein (PLP) , myelin proteolipid protein A , proteolipid protein 1 a , DMalpha1 , etID60288.14

GENE ID SPEZIES
5354 Homo sapiens
24943 Rattus norvegicus
281410 Bos taurus
397029 Sus scrofa
465785 Pan troglodytes
481002 Canis lupus familiaris
613099 Xenopus (Silurana) tropicalis
100009169 Oryctolagus cuniculus
100173486 Pongo abelii
100174736 Pongo abelii
18823 Mus musculus
396214 Gallus gallus
10903177 Trichinella spiralis
100136749 Oncorhynchus mykiss
398334 Xenopus laevis
100220245 Taeniopygia guttata
64264 Danio rerio
100714212 Cavia porcellus
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