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Protein tyrosine Phosphatase Type IVA, Member 2 Proteine (PTP4A2)

The protein encoded by PTP4A2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen Protein tyrosine Phosphatase Type IVA, Member 2 Antikörper (70) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PTP4A2 19244 O70274
PTP4A2 85237 Q6P9X4
PTP4A2 8073 Q12974
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Top Protein tyrosine Phosphatase Type IVA, Member 2 Proteine auf antikoerper-online.de

Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human GST tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$437.80
Details
Escherichia coli (E. coli) Human GST tag Human PTP4A2, GST Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$275.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human PTP4A2 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$540.11
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,374.17
Details
Escherichia coli (E. coli) Human GST tag   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$212.50
Details

PTP4A2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Rat (Rattus)

Human , , ,
, , ,

Weitere Proteine zu Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Interaktionspartnern

Mouse (Murine) Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Interaktionspartner

  1. a critical role for PRL2 phosphatase in mediating Notch and c-Kit signals in early T cell progenitors, is reported.

  2. Oncogenic PRL-2 controls tumor growth by modulating intracellular magnesium levels through binding with the CNNM3 (zeige CNNM3 Proteine) magnesium transporter.

  3. PTP4A2 plays critical roles in regulating hematopoietic stem cell self-renewal and mediating SCF (zeige KITLG Proteine)/KIT signaling.

  4. PRL2 promotes Kit-mediated PI3K/Akt signaling by reducing the level of PTEN that normally antagonizes the pathway.

  5. Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin (zeige TNS1 Proteine) Homologue Deleted on Chromosome 10) and activating Akt (zeige AKT1 Proteine) protein

Human Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Interaktionspartner

  1. identified a critical role for PRL2 phosphatase in the proliferation and survival of human AML cells. Further, we demonstrated that PRL2 is essential for the leukemogenic potential of AML1-ETO9a in vivo

  2. Our findings highlight the important role of miR (zeige MLXIP Proteine)-29c in regulating CRC (zeige CALR Proteine) EMT (zeige ITK Proteine) via GSK-3b/b-catenin signaling by targeting GNA13 (zeige GNA13 Proteine) and PTP4A and provide new insights into the metastatic basis of colorectal cancer

  3. PTP4A2 expression is correlated with overall survival in progestin receptor-positive breast carcinomas.

  4. Results suggest that TRP32 (zeige TXNL1 Proteine) maintains the reduced state of PRL (zeige PRL Proteine) and thus regulates the biological function of PRL (zeige PRL Proteine).

  5. Studies indicate that PRL-1 (zeige PLRG1 Proteine) and PRL-2 and PRL-3 are oncogenes and belong to the few phosphatases that lead to the development of cancer.

  6. Results suggest a model in which PRL-2 promotes cell migration and invasion through an ERK1/2-dependent signaling pathway.

  7. PRL-2 plays an important role in lung cancer and can be a biomarker of lung cancer, substituting for the function of other PRLs.

  8. Overexpression of the protein tyrosine phosphatase (zeige ACP1 Proteine) PRL-2 correlates with breast tumor formation and progression.

  9. Mouse pre-B-cells transfected with human PRL-2 had higher growth responses to Epo (zeige EPO Proteine) or IL-3 (zeige IL-3 Proteine), shorter cell cycle, less Epo (zeige EPO Proteine) requirement for survival, more cell migration, less cell adhesion, change to an immature cell morphology, & more Bmi-1 (zeige BMI1 Proteine) expression.

  10. PRL-2 can promote cell adhesion and invasion activity of human hepatocellular carcinoma cells.

Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

Genbezeichner und Symbole assoziert mit PTP4A2

  • protein tyrosine phosphatase type IVA, member 2b (ptp4a2b)
  • protein tyrosine phosphatase 4a2 (ptp4a2)
  • protein tyrosine phosphatase type IVA, member 2 (PTP4A2)
  • protein tyrosine phosphatase type IVA, member 2 L homeolog (ptp4a2.L)
  • protein tyrosine phosphatase type IVA, member 2 (ptp4a2)
  • protein tyrosine phosphatase 4a2 (Ptp4a2)
  • protein tyrosine phosphatase type IVA, member 2 (Ptp4a2)
  • HH7-2 Protein
  • HH13 Protein
  • HU-PP-1 Protein
  • MGC53390 Protein
  • MGC80084 Protein
  • MGC132077 Protein
  • OV-1 Protein
  • PRL-2 Protein
  • PRL2 Protein
  • ptp-IV1a Protein
  • ptp-IV1b Protein
  • PTP4A Protein
  • ptp4a2 Protein
  • PTPCAAX2 Protein
  • wu:fc05f09 Protein
  • wu:fi84b06 Protein
  • zgc:101724 Protein

Bezeichner auf Proteinebene für PTP4A2

PRL-2 , fc05f09 , protein tyrosine phosphatase type IVA 2 , protein tyrosine phosphatase 4a2 , protein tyrosine phosphatase type IVA, member 2 , protein-tyrosine phosphatase 4a2 , protein-tyrosine phosphatase of regenerating liver 2 , PTP(CAAXII) , phosphatase of regenerating liver 2 , protein tyrosine phosphatase IVA , protein tyrosine phosphatase IVA2

GENE ID SPEZIES
334483 Danio rerio
379932 Xenopus laevis
419649 Gallus gallus
443874 Xenopus laevis
454687 Pan troglodytes
549961 Xenopus (Silurana) tropicalis
609835 Canis lupus familiaris
19244 Mus musculus
85237 Rattus norvegicus
8073 Homo sapiens
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