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The protein encoded by PTPRG is a member of the protein tyrosine phosphatase (PTP) family.
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
, protein tyrosine phosphatase gamma
, protein tyrosine phosphatase, receptor type, gamma polypeptide
, protein-tyrosine phosphatase gamma
, receptor type protein tyrosine phosphatase gamma
, receptor tyrosine phosphatase gamma
, receptor-type protein phosphatase gamma
, receptor-type tyrosine-protein phosphatase gamma
, Protein-tyrosine phosphatase gamma precursor (R-PTP-gamma)
, RPTP gamma A
, RPTP gamma B
, RPTP gamma C
, RPTP gamma S
, receptor-like protein tyrosine phosphatase gamma