Protein tyrosine Phosphatase, Receptor Type, A Proteine (PTPRA)

The protein encoded by PTPRA is a member of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen PTPRA Antikörper (111) und PTPRA Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PTPRA 5786 P18433
PTPRA 19262 P18052
PTPRA 25167  
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Showing 9 out of 13 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 56 bis 61 Tage
5.753,97 €
Details
HOST_Baculovirus infected Insect Cells Human GST tag,His tag 50 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.149,36 €
Details
HOST_Escherichia coli (E. coli) Human GST tag   5 μg Anmelden zum Anzeigen 6 bis 8 Tage
306,74 €
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
542,86 €
Details
HOST_Escherichia coli (E. coli) Ratte Unkonjugiert   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
588,57 €
Details

PTPRA Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , , , ,
Mouse (Murine) ,
,
Rat (Rattus) ,

Weitere Proteine zu Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) Interaktionspartnern

Human Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) Interaktionspartner

  1. A receptor type-protein tyrosine phosphatase alpha-Src family kinase-Rap1 pathway was identified as responsible for recruiting myosin IIB to the zonula adherens in epithelial cells and supporting contractile tension.

  2. no evidence was seen for the association of rare, missense mutations in the PTPRA gene with schizophrenia or autism spectrum disorders

  3. Data indicate that scaffold protein (zeige HOMER1 Proteine) RACK1 (zeige GNB2L1 Proteine) plays a role in IGF-1 (zeige IGF1 Proteine)-mediated protein-tyrosine phosphatase alpha (PTPalpha) tyrosine phosphorylation in MCF-7 Cells.

  4. recruited to epithelial adherens junctions for cadherin-dependent cell adhesion and tissue architecture formation

  5. Results suggest that inhibition of PTPalpha can have a beneficial effect on HER2 (zeige ERBB2 Proteine)-positive breast cancers, but that inhibition of additional targets is needed to block breast tumorigenesis.

  6. new role for PTPalpha in the regulation of motility of mammary epithelial cells in response to ErbB2 (zeige ERBB2 Proteine) activation.

  7. results suggest that PTPalpha links activation of epidermal growth factor receptor (EGFR (zeige EGFR Proteine)) signaling with Src (zeige SRC Proteine) activation and may provide a novel therapeutic target for treatment of breast cancer.

  8. A single-nucleotide polymorphism (rs6138953) on the PTPRA gene in the 20p13 region was found to be associated with elevated fasting glucose level.

  9. The extracellular proteolytic processing is a novel mechanism for PTPalpha regulation.

  10. our results suggest that plasma PTPalpha and fibronectin (zeige FN1 Proteine) may be associated with opisthorchiasis.

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) Interaktionspartner

  1. RPTPalpha mediates proinflammatory and proinvasive signaling in rheumatoid arthritis fibroblast-like synoviocytes (FLS), correlating with the promotion of disease in an FLS-dependent model of rheumatoid arthritis.

  2. Ptpra coordinates the regulation of the Fyn (zeige FYN Proteine) signaling pathway in corpus striatum.

  3. PTPs (zeige PTS Proteine) alpha and epsilon play distinct roles in osteoclasts.

  4. PTP (zeige SLC25A3 Proteine)-alpha promotes profibrotic signaling pathways in fibroblasts through control of cellular responsiveness to TGF-beta (zeige TGFB1 Proteine).

  5. The focal adhesion targeting domain of FAK (zeige PTK2 Proteine) interacts with protein-tyrosine phosphatase-alpha to restrict IL1 (zeige IL1A Proteine)-induced Ca2 (zeige CA2 Proteine)+ release, ERK (zeige EPHB2 Proteine) activation, and MMP-9 (zeige MMP9 Proteine) expression.

  6. PTPalpha may be involved in the formation of axoglial junctions and ensheathment in small axons during myelination of the spinal cord.

  7. Findings indicate Grb2 (zeige GRB2 Proteine) as a new FAK (zeige PTK2 Proteine) activator and in coordinating PTPalpha tyrosine phosphorylation to enable downstream integrin signaling and migration.

  8. Results suggest that inhibition of PTPalpha can have a beneficial effect on HER2 (zeige ERBB2 Proteine)-positive breast cancers, but that inhibition of additional targets is needed to block breast tumorigenesis.

  9. Inflammation-induced connective tissue degradation involving fibroblasts requires functionally active PTPalpha.

  10. study described a molecular complex of PTPalpha-BCAR3 (zeige BCAR3 Proteine)-Cas (zeige CTNND1 Proteine)-Src (zeige SRC Proteine); this complex forms in response to PTPalpha Tyr789 phosphorylation and mediates Cas (zeige CTNND1 Proteine) localization to focal adhesions and Cas (zeige CTNND1 Proteine) downstream signaling to promote cell migration

Zebrafish Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) Interaktionspartner

  1. ptpra protein, zebrafish, signaling is essential for convergence and extension cell movements during gastrulation.

PTPRA Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Genbezeichner und Symbole assoziert mit PTPRA

  • protein tyrosine phosphatase, receptor type, A (PTPRA)
  • protein tyrosine phosphatase, receptor type, A (ptpra)
  • protein tyrosine phosphatase, receptor type, A (Ptpra)
  • HEPTP Protein
  • HLPR Protein
  • HPTPA Protein
  • HPTPalpha Protein
  • LRP Protein
  • Ptpa Protein
  • ptpa-a Protein
  • Ptpalpha Protein
  • PTPRA Protein
  • PTPRL2 Protein
  • R-PTP-alpha Protein
  • RPTPA Protein
  • Rptpalpha Protein
  • RPTP[a] Protein
  • Rptra Protein
  • Rptralpha Protein
  • zf-RPTP[a] Protein

Bezeichner auf Proteinebene für PTPRA

protein tyrosine phosphatase, receptor type, A , receptor-type tyrosine-protein phosphatase alpha-like , Leukocyte common antigen-related peptide (protein tyrosine phosphate) , PTPLCA-related phosphatase , PTPase-alpha , protein tyrosine phosphatase, receptor type, alpha polypeptide , protein-tyrosine phosphatase alpha , receptor-type tyrosine-protein phosphatase alpha , tyrosine phosphatase alpha , LCA-related phosphatase , PTPTY-28 , R-PTP-alpha , protein tyrosine phosphatase alpha , protein tyrosine phosphatase receptor type alpha , protein-tyrosine-phosphatase alpha

GENE ID SPEZIES
100066880 Equus caballus
574364 Macaca mulatta
746684 Pan troglodytes
100017832 Monodelphis domestica
100158513 Xenopus (Silurana) tropicalis
100342875 Oryctolagus cuniculus
100373726 Saccoglossus kowalevskii
100404748 Callithrix jacchus
100449130 Pongo abelii
100464070 Ailuropoda melanoleuca
100605844 Nomascus leucogenys
5786 Homo sapiens
19262 Mus musculus
25167 Rattus norvegicus
140818 Danio rerio
394358 Xenopus laevis
396060 Gallus gallus
477176 Canis lupus familiaris
100138017 Bos taurus
100157496 Sus scrofa
Ausgewählte Anbieter für PTPRA Proteine (PTPRA)
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