Protein S Proteine (PROS)

PROS encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. Zusätzlich bieten wir Ihnen PROS1 Antikörper (169) und PROS1 Kits (55) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PROS 5627 P07225
PROS 81750  
PROS 19128 Q08761
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Top PROS1 Proteine auf antikoerper-online.de

Showing 10 out of 20 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 2 bis 3 Tage
$547.80
Details
Escherichia coli (E. coli) Ratte His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$640.00
Details
Hefe Ratte His tag Protein S (Alpha) (PROS1) (AA 42-675) protein (His tag) expressed in mammalien cells 1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,835.33
Details
Human Cells Human His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
Escherichia coli (E. coli) Human His-SUMO Tag 100 μg Anmelden zum Anzeigen 11 Days
$411.40
Details
Escherichia coli (E. coli) Ratte GST tag 100 μg Anmelden zum Anzeigen 11 Days
$581.90
Details
Mammalian Cells Ratte His tag 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$1,490.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

PROS Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
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Rat (Rattus) , ,
, , ,
Mouse (Murine)

Am meisten referenzierte PROS1 Proteine

  1. Human PROS1 Protein expressed in HEK-293 Cells - ABIN2729817 : Kariolis, Miao, Jones, Kapur, Mathews, Giaccia, Cochran: An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis. in Nature chemical biology 2014 (PubMed)

Weitere Proteine zu Protein S (PROS) Interaktionspartnern

Human Protein S (PROS) Interaktionspartner

  1. The present case combined with the review of the literature suggests that p.Arg451* in the PROS1 (zeige PROS1 zeige) gene mainly leads to clinically evident thrombosis following trauma, surgery or serious comorbidities especially malignancy.

  2. Protein S and Gas6 (zeige GAS6 Proteine) mediates phagocytosis of HIV-1-infected cells by bridging receptor tyrosine kinase (zeige RET Proteine) Mer (zeige MERTK Proteine) to phosphatidylserine exposed on infected cells.

  3. these results suggest a novel pathogenic role of SPE B that initiates protein S degradation followed by the inhibition of apoptotic cell clearance by macrophages

  4. Developed functional protein S assays that measure both the activated protein C (zeige PROC Proteine)- and TFPI (zeige TFPI Proteine)-cofactor activities of protein S in plasma, which are hardly if at all affected by the FV Leiden mutation.

  5. Taken together, our gain-of-function, loss-of-function analyses suggest that PROS may facilitate cell proliferation and promote castration resistance in human castration-resistant PCa (zeige FLVCR1 Proteine)-like cells via its apoptosis-regulating property.

  6. we identify PROS1 (zeige PROS1 Proteine) as a driver of Oral Squamous Cell Carcinoma tumor growth and a modulator of AXL (zeige AXL Proteine) expression

  7. The prevalence of PS de fi ciency in the present study was higher than in Western countries and con (zeige DISP1 Proteine) fi rms the high prevalence of PS de fi ciency in Asian populations

  8. In the present study, gene analysis of six unrelated Japanese families diagnosed with congenital protein S deficiency identified five missense mutations in the PROS1 (zeige PROS1 zeige) gene - c.757C>T (Ala139Val; A139V), c.1346 G>T (Cys449Phe; C449F), c.1352G>A (Arg451Gln; R451Q), c.1424G>T (Cys475Phe; C475F) and c.1574C>T (Ala525Val; A525V) - and one frameshift mutation, c.2135delA (Asp599ThrfsTer13; D599TfsTer13).

  9. The odds ratio of developing idiopathic fatal pulmonary embolism as a variant carrier for PROS1 (zeige PROS1 zeige) is 56.4 (95% CI, 5.3-351.1; P = 0.001).

  10. described a novel PROS1 (zeige PROS1 zeige) frameshift mutation, c.74dupA, in a hereditary protein S deficiency family. Interestingly, both of the proband and his mother carried the mutation and had a protein S deficiency, however, only the proband suffered a pulmonary embolism while his mother had no history of any thrombosis, suggesting that a triggering event might have been involved in the thrombus formation.

PROS1 (PROS) Protein Überblick

Protein Überblick

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.

Genbezeichner und Symbole assoziert mit Protein S Proteine (PROS)

  • protein S (PROS1)
  • protein S (Pros1)
  • protein S (pros1)
  • protein S (alpha) (Pros1)
  • AW214361 Protein
  • PROS Protein
  • PS21 Protein
  • PS22 Protein
  • PS23 Protein
  • PS24 Protein
  • PS25 Protein
  • PSA Protein
  • THPH5 Protein
  • THPH6 Protein
  • zgc:154001 Protein

Bezeichner auf Proteinebene für Protein S Proteine (PROS)

protein Sa , vitamin K-dependent plasma protein S , vitamin K-dependent protein S

GENE ID SPEZIES
5627 Homo sapiens
81750 Rattus norvegicus
768180 Danio rerio
19128 Mus musculus
100009314 Oryctolagus cuniculus
Ausgewählte Anbieter für PROS1 Proteine (PROS)
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