Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E Proteine (PPM1E)

PPM1E encodes a member of the PPM family of serine/threonine-protein phosphatases. Zusätzlich bieten wir Ihnen PPM1E Antikörper (21) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PPM1E 320472 Q80TL0
PPM1E 22843  
PPM1E 360593 Q80Z30
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$4,194.67
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PPM1E Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human

Rat (Rattus)

Weitere Proteine zu Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E (PPM1E) Interaktionspartnern

Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E (PPM1E) Interaktionspartner

  1. Ppm1E upregulation in human gastric cancer is important for cell proliferation, possible via regulating AMPK-mTOR signaling.

  2. miR-135b-5p expression downregulates Ppm1e to activate AMPK signaling, which inhibits LPS-induced TNFalpha production via suppressing ROS production and NFkappaB activation.

  3. our results suggest that miR-135b-induced Ppm1e silence induces AMPK activation to inhibit osteoblastoma cell proliferation.

  4. Data show that miR-135b selectively targets the AMPK phosphatase Ppm1e.

  5. The Ppm1E contributes to dephosphorylation of AMP-activated protein kinase.

  6. The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family. (POPX1; POPX2)

PPM1E Protein Überblick

Protein Überblick

This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.

Genbezeichner und Symbole assoziert mit PPM1E

  • protein phosphatase 1E (PP2C domain containing) (Ppm1e)
  • protein phosphatase, Mg2+/Mn2+ dependent 1E (PPM1E)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1E (Ppm1e)
  • AW049266 Protein
  • B930008A12Rik Protein
  • caMKN Protein
  • CaMKP-N Protein
  • mKIAA1072 Protein
  • POPX1 Protein
  • PP2CH Protein

Bezeichner auf Proteinebene für PPM1E

ca(2+)/calmodulin-dependent protein kinase phosphatase N , caMKN , caMKP-N , caMKP-nucleus , partner of PIX 1 , partner of PIX-alpha , partner of PIXA , protein phosphatase 1E , nuclear calmodulin-dependent protein kinase phosphatase , protein phosphatase 1E (PP2C domain containing) , calmodulin-dependent protein kinase phosphatase N

GENE ID SPEZIES
320472 Mus musculus
22843 Homo sapiens
360593 Rattus norvegicus
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