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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) ELISA Kits

The protein encoded by PPM1A is a member of the PP2C family of Ser/Thr protein phosphatases. Zusätzlich bieten wir Ihnen Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Antikörper (111) und Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Proteine (18) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus PPM1A PPM1A 19042 P49443
PPM1A 5494 P35813
PPM1A 24666 P20650
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.123 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$589.47
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Ratte 0.119 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$640.00
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Am meisten referenzierte Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A ELISA Kits

  1. Human PPM1A ELISA Kit für Sandwich ELISA - ABIN422937 : Kim, Sohn, Zhao, Sokolove, Lindstrom, Yoo, Lee, Reveille, Taurog, Robinson: Role of protein phosphatase magnesium-dependent 1A and anti-protein phosphatase magnesium-dependent 1A autoantibodies in ankylosing spondylitis. in Arthritis & rheumatology (Hoboken, N.J.) 2014 (PubMed)

Weitere ELISA Kits für Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Interaktionspartner

Mouse (Murine) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Interaktionspartner

  1. findings demonstrate a novel regulatory circuit in which STING and TBK1 (zeige TBK1 ELISA Kits) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A dephosphorylates STING and TBK1 (zeige TBK1 ELISA Kits)

  2. the studies presented here position PPM1A as a new player in the wound healing-inflammation-angiogenesis axis in mouse, reveal its crucial role in homeostasis on injury, and highlight its potential as a therapeutic mediator in pathologic conditions

  3. a nuclear envelope-localized mechanism of inactivating TGF-beta (zeige TGFB1 ELISA Kits) signaling in which MAN1 (zeige LEMD3 ELISA Kits) competes with transcription factors for binding to Smad2 (zeige SMAD2 ELISA Kits) and Smad3 (zeige SMAD3 ELISA Kits) and facilitates their dephosphorylation by PPM1A.

  4. Although a non-myristoylated mutation (G2A) of PPM1A and PPM1B prevented membrane association, this relocalization did not likely cause the decreased activity towards AMPKalpha.

  5. we found that PPM1A mRNA is synthesized at the beginning of the maturation process and remains elevated in the mature oocytes, promoting the accumulation of PPM1A protein

  6. Protein phosphatase PPM1A regulates the nuclear export of Smad2/3 through targeting nuclear exporter RanBP3.

  7. Ppm1a, through suppressing Smad2 (zeige SMAD2 ELISA Kits) signaling, plays a critical role in re-epithelialization during wound healing

  8. Molecular cloning and expression analysis of MPP alpha-2, a novel transcript detected in a differential screen of pituitary libraries (MPPalpha 2)

  9. Protein phosphatase 1alpha is required for lung growth and morphogenesis.

Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Interaktionspartner

  1. Present study suggests that HBx-induced degradation of PPM1a is a novel mechanism for over-activation of TGF-beta pathway in HCC development.

  2. Findings show that HCV infection and replication decreased PPM1A abundance, mediated by NS3, in hepatoma cells. Compared to normal liver tissues, the expression of PPM1A was significantly decreased in the HCC tumor tissues and adjacent non-tumor tissues through its regulation by NS3 which promotes its ubiquitination and proteasomal degradation.

  3. These data suggest that PPM1A, which had previously been shown to play a role in the antiviral response to Herpes Simplex virus infection, also governs the antibacterial response of macrophages to bacteria, or at least to Mycobacterium tuberculosis infection

  4. establish PPM1A as a novel repressor of the SMAD3 (zeige SMAD3 ELISA Kits) pathway in renal fibrosis

  5. Report a tumor-suppressive function of PPM1A and an independent relationship to Smad4 (zeige SMAD4 ELISA Kits) in pancreatic ductal adenocarcinoma.

  6. hydrogen/deuterium exchange-mass spectrometry and molecular dynamics to characterize conformational changes in PP2Calpha between the active and inactive states

  7. In a nested case control study of ischemic stroke, there was an epigenome-wide association for cg04985020 (PPM1A; P=1.78x10(-07)) with vascular recurrence in patients treated with aspirin.

  8. findings demonstrate a novel regulatory circuit in which STING and TBK1 (zeige TBK1 ELISA Kits) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A dephosphorylates STING and TBK1 (zeige TBK1 ELISA Kits)

  9. The TGF-beta (zeige TGFB1 ELISA Kits)/Smad (zeige SMAD1 ELISA Kits) signaling system decreases its activity through strong negative regulation. We provide evidence for a new negative feedback loop through PPM1A upregulation.

  10. Loss of PPM1A is associated with the development of tumor invasion in bladder cancer patients.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Genbezeichner und Symbole assoziert mit PPM1A

  • protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A) Antikörper
  • protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1A (Ppm1a) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog (ppm1a.L) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent 1A (Ppm1a) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Aa (ppm1aa) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Bb (ppm1bb) Antikörper
  • 2310003C21Rik Antikörper
  • 2900017D14Rik Antikörper
  • AI427932 Antikörper
  • AU017636 Antikörper
  • fc18g04 Antikörper
  • MMPa-2 Antikörper
  • MPPa-1 Antikörper
  • pp2c-alpha Antikörper
  • Pp2c1 Antikörper
  • pp2ca Antikörper
  • pp2ca2 Antikörper
  • pp2calpha Antikörper
  • ppm1a Antikörper
  • wu:fc18g04 Antikörper
  • zgc:92329 Antikörper

Bezeichner auf Proteinebene für PPM1A

Mpp alpha , PP2C-alpha , protein phosphatase 1A , protein phosphatase 2C isoform alpha , protein phosphatase IA , protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform , IA , Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform , Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform , protein phosphatase 1A, magnesium dependent, alpha isoform , protein phosphatase 2C alpha , protein phosphatase type 2C alpha 2 , protein phosphatase 1A, magnesium dependent, alpha

GENE ID SPEZIES
100738389 Sus scrofa
19042 Mus musculus
5494 Homo sapiens
24666 Rattus norvegicus
380058 Xenopus laevis
423525 Gallus gallus
480344 Canis lupus familiaris
281994 Bos taurus
100009431 Oryctolagus cuniculus
100734826 Cavia porcellus
30704 Danio rerio
100003481 Danio rerio
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