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Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. Zusätzlich bieten wir Ihnen und Proteasome-Associated Protein ECM29 Homolog Proteine (1) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal KIAA0368 Primary Antibody für IHC - ABIN966026
Ohara, Ohara, Yamakawa, Nakajima, Nakayama: Characterization of a new beta-spectrin gene which is predominantly expressed in brain. in Brain research. Molecular brain research 1998
Show all 3 Pubmed References
Data suggest that the adapter protein (zeige TOLLIP Antikörper) ECM29 is the main proteasome-interacting protein responsible for oxidative stress-induced (zeige SQSTM1 Antikörper) proteasome disassembly/remodeling; ECM29 appears to intrude on interaction between the 20S core particle and 19S regulatory particle in 26S proteasome (zeige Psmd4 Antikörper), disrupting proteasome structure in response to oxidative stress.
Ecm29 is involved in the dissociation process of 26S proteasome (zeige Psmd4 Antikörper), providing clue to analyse the mechanism of proteasomal degradation under various stress condition.
The absence of Ecm29 enhanced TLR3 (zeige TLR3 Antikörper) signaling, which was characterized by the increased abundance of the adaptor protein and E3 ubiquitin ligase (zeige MUL1 Antikörper) tumor necrosis factor (zeige TNF Antikörper) receptor-associated factor 3
Ecm29 serves as an adaptor for coupling 26 S proteasomes to specific cellular compartments.
Ecm29 protein serves to couple the 26 S proteasome to secretory compartments engaged in quality control and to other sites of enhanced proteolysis
Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolyis (By similarity).
proteasome-associated protein ECM29 homolog
, Proteasome-associated protein ECM29 homolog
, ECM29 homolog, proteasome accessory protein
, homolog of yeast Ecm29