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PRSS3 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. Zusätzlich bieten wir Ihnen PRSS3 Proteine (9) und PRSS3 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 89 products:
PRSS3 acts as an oncogene (zeige RAB1A Antikörper) in invasive ductal carcinoma of the breast development and progression
Study developed a new high resolution crystal structure of mesotrypsin complexed with diminazene through a structure-based molecular docking screen that could help facilitate derivatization efforts, addressing current pan (zeige SUPT6H Antikörper)-inhibition of human trypsins through rigidification of diminazene to select for a conformation that maximizes interactions with the non-conserved Arg-193 residue.
Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 accumulated tissue factor pathway inhibitor-2 (TFPI-2 (zeige TFPI2 Antikörper)) in the matrix.
These findings suggest that inhibitor cleavage represents a functional adaptation of mesotrypsin that may have evolved in response to positive selection pressure.
High PRSS3 expression in EOC tissues was significantly associated with advanced FIGO stage and lymph node metastasis.
Data suggest that mesotrypsin cleavage of Kunitz domains may contribute to cancer progression.
Mesotrypsin generated saposins A-D from prosaposin (zeige PSAP Antikörper), and mature caspase-14 (zeige CASP14 Antikörper) contributed to this process by activating mesotrypsinogen to mesotrypsin. Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.
extra-pancreatic trypsinogen 3 is produced by esophageal adenocarcinoma cells and activates PAR-2 (zeige F2RL1 Antikörper) in an autocrine manner.
IFN regulatory factor 2 (Irf2 (zeige IRF2 Antikörper)) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3 (zeige SPINK1 Antikörper)
Report PRSS3/mesotrypsin upregulation in breast cancer cells and identify CD109 (zeige CD109 Antikörper) as the functional proteolytic target of mesotrypsin.
Intra-acinar activation of trypsinogen is sufficient to initiate acute pancreatitis.
the initiation of acute pancreatitis depends on endocytic vacuole formation and trypsinogen activation in pancreatic acinar cells
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.
, brain trypsinogen
, pancreatic trypsinogen III
, protease, serine, 4 (trypsin 4, brain)
, trypsin III
, trypsin IV
, trypsinogen 4
, trypsinogen 5
, trypsinogen IV
, trypsin 3
, trypsinogen 15
, cationic trypsin III
, cationic trypsin-3
, cationic trypsinogen
, pretrypsinogen III