anti-Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4) Antikörper

The protein encoded by PTGER4 is a member of the G-protein coupled receptor family. Zusätzlich bieten wir Ihnen PTGER4 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTGER4 5734 P35408
PTGER4 19219 P32240
PTGER4 84023 P43114
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Top anti-PTGER4 Antikörper auf antikoerper-online.de

Showing 10 out of 79 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN185578 (0.1µg/ml) staining of Human Testes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of EP4 expression in Ramos (A), HeLa (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from COLO205 cells, using PE2R4 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of MCF7 cells, using PE2R4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NBP1-84833] - Staining of human small intestine shows strong cytoplasmic and membranous positivity in glandular cells. Western Blot: PTGER4/EP4 Antibody [NBP1-84833] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3890] - Analysis of anti-PTGER4 / EP4 antibody with human colon, ganglion at 2 ug/ml. Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody  - Anti-PTGER4 / EP4 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p) Immunocytochemistry/Immunofluorescence: PTGER4/EP4 Antibody [NLS3898] - Analysis of anti-PTGER4 / EP4 antibody with transfection control. Immunocytochemistry/Immunofluorescence: PTGER4/EP4 Antibody [NLS3898] - Analysis of anti-PTGER4 / EP4 antibody with transfected cells expressing Prostaglandin E Receptor EP4 at 8 ug/ml. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Anti-PTGER4 / EP4 antibody  ABIN1049259 IHC staining of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ICC, IHC (p) Anti-PTGER4 / EP4 antibody  ABIN1049261 IHC staining of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ICC, IHC (p) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details

PTGER4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine) ,
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Rat (Rattus) ,


Am meisten referenzierte anti-PTGER4 Antikörper

  1. Human Polyclonal PTGER4 Primary Antibody für WB - ABIN1881704 : Bastien, Sawyer, Grygorczyk, Metters, Adam: Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype. in The Journal of biological chemistry 1994 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal PTGER4 Primary Antibody für ELISA, WB - ABIN251245 : Parida, Parekh, Dey, Ghosh, Mandal: Molecular inhibition of prostaglandin E2 with GW627368X: Therapeutic potential and preclinical safety assessment in mouse sarcoma model. in Cancer biology & therapy 2015 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal PTGER4 Primary Antibody für ICC, IF - ABIN4348399 : Prijatelj, Celhar, Mlinaric-Rascan: Prostaglandin EP4 receptor enhances BCR-induced apoptosis of immature B cells. in Prostaglandins & other lipid mediators 2011 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal PTGER4 Primary Antibody für WB - ABIN519449 : Xiao, Li, Jones-Brando, Yolken: Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains. in Journal of neural transmission (Vienna, Austria : 1996) 2013 (PubMed)

  5. Cow (Bovine) Polyclonal PTGER4 Primary Antibody für IHC (p) - ABIN4348398 : Oll, Baumann, Behbahani, von Ruecker, Müller, Ellinger: Identification of prostaglandin receptors in human ureters. in BMC urology 2013 (PubMed)

Weitere Antikörper gegen PTGER4 Interaktionspartner

Zebrafish Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4) Interaktionspartner

  1. Lkt/ABCC4 (zeige ABCC4 Antikörper)-mediated PGE2 signalling acts through a ciliary G-protein-coupled receptor (zeige GPBAR1 Antikörper), EP4, to upregulate cAMP synthesis and increase anterograde intraflagellar transport, thereby promoting ciliogenesis.

  2. Ep4a, a PGE2 receptor isoform of EP4, is involved in lymphoid precursor development in zebrafish.

Human Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4) Interaktionspartner

  1. Reprogramming of mammary epithelial cells can result from EP4 -mediated stem cell property transfer by extracellular vesicles/exosomes containing caveolae-associated proteins, between mammary basal and luminal epithelial cells.

  2. High PTGER4 methylation is associated with Lung cancer.

  3. in breast cancer cells overexpression of S1P3 (zeige S1PR3 Antikörper) and its activation by S1P (zeige MBTPS1 Antikörper) has pro-inflammatory and pro-metastatic potential by inducing COX-2 (zeige COX2 Antikörper) expression and PGE2 signaling via EP2 (zeige SPAG11B Antikörper) and EP4.

  4. These results indicate that the blockage of PGE2-EP4 signaling prevents the bone destruction required for prostate cancer metastases, and that this is, in part due to the abrogation of bone cell responses. The study provides further evidence that an EP4 antagonist is a candidate for the treatment of prostate cancer in the blockade of bone metastasis.

  5. The results show that stimulation with the selective EP4 agonist CAY10598 or PGE2 promotes invadopodia-mediated degradation of the ECM (zeige MMRN1 Antikörper), as well as the invasion of breast cancer cells in in vitro models.

  6. EP4 expression can promote the development of resistance to aromatase (zeige CYP19A1 Antikörper) inhibitor therapy for breast cancer

  7. Findings suggest SUMO-1 (zeige SUMO1 Antikörper) protein and PGE2 receptor subtype 4 (EP4) as two potential targets for new therapeutic or prevention strategies for endometrial cancers.

  8. GW627368X therefore effectively inhibits cervical cancer survival, motility, proliferation and angiogenesis by blocking EP4/EGFR (zeige EGFR Antikörper) interactive signaling.

  9. The cross-talk between SP1 (zeige PSG1 Antikörper) and p65 (zeige GORASP1 Antikörper), and the positive feedback regulatory loop of PI3-K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) signaling by EP4 contribute to the overall responses of solamargine in this process

  10. The PTGER4 gene is a candidate risk factor for radiological progression in rheumatoid arthritis

Mouse (Murine) Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4) Interaktionspartner

  1. Paricalcitol also attenuated the infiltration of inflammatory cells and production of proinflammatory cytokines after IR injury. EP4 antagonist abolished these antioxidant, anti-inflammatory, and antiapoptotic effects. The EP4 plays a pivotal role in the protective effects of paricalcitol in renal IR injury.

  2. These results demonstrate a novel role for prostaglandin receptor EP4 in the mediation of barrier-enhancing and anti-inflammatory effects caused by oxidized phospholipids.

  3. The deletion of EP4 increases mitochondrial biogenesis and oxidative capacity in WAT, and fat mass loss ensues in mice.

  4. Myeloid cell Ptger4 modulates interleukin production but not atherogenesis in type I diabetic mice.

  5. These data suggest that vascular EP4 receptors buffer the actions of AngII on renal hemodynamics and oxidative injury.

  6. these studies have demonstrated an important but unexpected role for macrophage COX-2 (zeige COX2 Antikörper)/prostaglandin E2/PGE2 receptor subtype 4 signaling to lessen progression of diabetic kidney disease, unlike the pathogenic effects of increased COX-2 (zeige COX2 Antikörper) expression in intrinsic renal cells.

  7. data demonstrate that endogenous PGE2, EP2 (zeige SPAG11A Antikörper) receptors, and EPAC (zeige RAPGEF3 Antikörper) are prerequisites for maximal LPS (zeige TLR4 Antikörper)-induced IL-33 (zeige IL33 Antikörper) expression and that exogenous PGE2 can amplify IL-33 (zeige IL33 Antikörper) production via EP2 (zeige SPAG11A Antikörper) and EP4 receptors.

  8. The data presented highlight a key role for EP2 (zeige SPAG11A Antikörper) and EP4 receptors in microvascular leak induced by PGE2.

  9. These results suggest that Il23a (zeige IL23A Antikörper) expression in DCs is synergistically triggered by the PG E2-EP4-cAMP-PKA pathway and canonical/non-canonical NF-kappaB (zeige NFKB1 Antikörper) pathways and CREB (zeige CREB1 Antikörper) activated by CD40 (zeige CD40 Antikörper) stimulation.

  10. autocrine prostaglandin E2 signaling through EP receptors is essential for optimal CD4 (zeige CD4 Antikörper)(+) T-cell activation.

Cow (Bovine) Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4) Interaktionspartner

  1. Data suggest that lysophosphatidic acid (LPA (zeige PLG Antikörper)) up-regulates expression of SLCO2A1 (zeige SLCO2A1 Antikörper) (prostaglandin [PG] transporter), PTGER2 (zeige PTGER2 Antikörper)/PTGER4 (PG receptors EP2 (zeige SPAG11A Antikörper)/EP4), and mPGES1 (zeige PTGES Antikörper)/cPGES (zeige PTGES3 Antikörper) (microsomal/cytosolic PG E synthases) in luteal cells.

  2. Data suggest that estradiol up-regulates mRNA and protein expression of 3 prostanoid receptors in oviduct smooth muscle: EP2/PTGER2 (zeige PTGER2 Antikörper) (prostaglandin E receptor 2); EP4/PTGER4 (prostaglandin E receptor 4); and FP/PTGFR (prostaglandin F2alpha receptor (zeige PTGFR Antikörper)).

  3. The PGE2-mediated down-regulation of CD25 (zeige IL2RA Antikörper) expression on T cells is mediated via the EP4 receptor, although selective activation of the EP2 receptor up-regulates the CD25 (zeige IL2RA Antikörper) expression on these cells.

  4. EP4 is undetectable in endometrium and myometrium during the estrous cycle

  5. Quantitative RT-PCR revealed significant higher expression of EP2 (zeige SPAG11A Antikörper) and EP4 in the pre-ovulatory phase compared with the luteal phase in the bovine oviduct

PTGER4 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.

Genbezeichner und Symbole assoziert mit PTGER4

  • prostaglandin E receptor 4 (PTGER4) Antikörper
  • prostaglandin E receptor 4 (subtype EP4) (PTGER4) Antikörper
  • prostaglandin E receptor 4 (subtype EP4) a (ptger4a) Antikörper
  • prostaglandin E receptor 4 (ptger4) Antikörper
  • prostaglandin E receptor 4 subtype EP4 (ptger4) Antikörper
  • prostaglandin E receptor 4 (subtype EP4) (Ptger4) Antikörper
  • prostaglandin E receptor 4 (Ptger4) Antikörper
  • ep4 Antikörper
  • EP4R Antikörper
  • PGE2R-EP4 Antikörper
  • Ptger Antikörper
  • PTGER4 Antikörper
  • ptger4l Antikörper
  • Ptgerep4 Antikörper

Bezeichner auf Proteinebene für PTGER4

prostaglandin E receptor 4, subtype EP4 , prostaglandin E2 receptor EP4 subtype , prostaglandin E2 receptor subtype 4 , prostaglandin E receptor 4 (subtype EP4) , ep4 , ep4a , prostaglandin E receptor 4 , prostaglandin E receptor 4 subtype EP4 , PGE receptor EP4 subtype , PGE receptor, EP4 subtype , PGE2 receptor EP4 subtype , prostanoid EP4 receptor , prostaglandin E receptor 4 (EP4 subtype) , prostaglandin E receptor EP4 subtype , prostaglandin E2 receptor type 4 , PGE receptor, subtype EP4 , prostaglandin receptor EP4 subtype , prostaglandin E2 subtype EP4 receptor

GENE ID SPEZIES
427183 Gallus gallus
443222 Ovis aries
562469 Danio rerio
695220 Macaca mulatta
100145708 Xenopus (Silurana) tropicalis
100169968 Felis catus
100510774 Anolis carolinensis
5734 Homo sapiens
19219 Mus musculus
84023 Rattus norvegicus
403589 Canis lupus familiaris
282331 Bos taurus
100009081 Oryctolagus cuniculus
450195 Pan troglodytes
Ausgewählte Anbieter für anti-PTGER4 (PTGER4) Antikörper
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