Prostaglandin E Receptor 3 (Subtype EP3) Proteine (PTGER3)

The protein encoded by PTGER3 is a member of the G-protein coupled receptor family. Zusätzlich bieten wir Ihnen Prostaglandin E Receptor 3 (Subtype EP3) Antikörper (120) und Prostaglandin E Receptor 3 (Subtype EP3) Kits (23) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PTGER3 5733 P43115
Ratte PTGER3 PTGER3 24929 P34980
PTGER3 19218  
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Showing 6 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
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Escherichia coli (E. coli) Human His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$717.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Wheat germ Human Unkonjugiert   2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$491.43
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Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$318.85
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PTGER3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) Interaktionspartnern

Human Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) Interaktionspartner

  1. Study reports that EP3 expression is elevated in TSC2- deficient patient-derived cells compared with TSC2-addback cells, and that EP3 antagonist selectively suppresses the proliferation of TSC2-deficient cells. The elevated expression of EP3 is mediated by Rheb (zeige RHEB Proteine) in an mTORC1-independent fashion.

  2. Study showed the EP3 expression is correlated to the FIGO classification and, demonstrates that an increased EP3 expression correlates with a negative outcome of overall survival of cervical carcinoma patients. In addition, different expression of EP3 was found in correlation to the histological subtype. Patients with adenocarcinoma and high expression of EP3 had a worse outcome survival.

  3. EP2 (zeige SPAG11B Proteine) and EP3 receptors are involved in tolerance induction through IL-10 (zeige IL10 Proteine) production by tol-DCs.

  4. findings show that prostaglandin E2 EP3 receptor contributes to thrombin (zeige F2 Proteine)-induced brain damage via Rho-Rho kinase (zeige ROCK1 Proteine)-mediated cytotoxicity and proinflammatory responses.

  5. S211L within EP3 is the key residue to distinguish PGE1 and PGE2 binding to mediate diverse biological functions at the initial recognition step

  6. The present study identified the functions of EP3 and the mechanisms by which PGE2 regulates beta-catenin (zeige CTNNB1 Proteine) expression and promoted cholangiocarcinoma cell growth and invasion

  7. Our results show that oxLDL suppresses EP3 expression by activation of PPAR-g (zeige ARF6 Proteine) and subsequent inhibition of NF-kappaB (zeige NFKB1 Proteine) in macrophages.

  8. results demonstrate that risk of unsuccessful periodontal treatment is associated with tag SNPs in specific genes that regulate the inflammatory response, one of which is also associated with sPTB.

  9. Failure of cervical ripening, after local application of prostaglandins for labor induction, may be caused by the increased expression of EP3 and concomitant decrease in EP4 (zeige PTGER4 Proteine) expression.

  10. Human prostate cancer is associated with EP4 (zeige PTGER4 Proteine) and EP2 (zeige SPAG11B Proteine) overexpression and reduced EP3 expression.

Rabbit Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) Interaktionspartner

  1. For the mutant receptors, the second extracellular loop (ECII) plays a critical role in linking the agonist bound receptor conformation to the G protein nucleotide bound state.

Mouse (Murine) Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) Interaktionspartner

  1. GMSC administration promoted the expression of EP3.

  2. EP3 receptor and its alpha and gamma isoforms are involved in both adipogenesis and lipolysis and influence food intake, serum lipid levels, and insulin (zeige INS Proteine) sensitivity.

  3. PGE2 reduces contractility of the in vivo heart, the isolated working heart, and single adult ventricular myocytes via its EP3 receptor.

  4. Activation of the EP3 receptor facilitates sprouting angiogenesis through protein kinase A/beta (zeige SUCLA2 Proteine)-catenin (zeige CTNNB1 Proteine)/notch (zeige NOTCH1 Proteine) signaling.

  5. Data show that prostaglandin E2 receptor EP3 subtype (EP3) was expressed in the interstitial cells of Cajal (ICCs) of the bladder and activated hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.

  6. Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 (zeige CYSLTR1 Proteine) and E-prostanoid receptor 3

  7. Data (including data from studies in knockout mice) suggest that Ptger3 is involved in regulation of adiposity, lipid metabolism, and insulin (zeige INS Proteine) resistance; Ptger3 knockout mice gain more weight on high-fat diet than normal mice.

  8. EP3 activation facilitates hypoxia-induced vascular remodeling and pulmonary hypertension in mice.

  9. EP3 and TLR3 (zeige TLR3 Proteine) in conjunctival epithelium play a critical role in regulating ocular surface inflammation.

  10. PGE2 triggers mast cell activation via an EP3-Gi/o-Ca(2 (zeige CA2 Proteine)+) influx/PI3K pathway. This mechanism underlies PGE2-induced vascular permeability and consequent edema formation.

Pig (Porcine) Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) Interaktionspartner

  1. vasoconstriction is mediated by phosphatidyl-inositol pathway via activation of EP1 (zeige PTGER1 Proteine)- and EP3-receptors located on the smooth muscle cells

Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PTGER3

  • prostaglandin E receptor 3 (PTGER3)
  • prostaglandin E receptor 3 L homeolog (ptger3.L)
  • prostaglandin E receptor 3 (Ptger3)
  • prostaglandin E receptor 3 (subtype EP3) (Ptger3)
  • prostaglandin E receptor 3 (subtype EP3) (PTGER3)
  • EP3 Protein
  • EP3-I Protein
  • EP3-II Protein
  • EP3-III Protein
  • EP3-IV Protein
  • EP3e Protein
  • PGE2-R Protein
  • Pgerep3 Protein
  • PTGER3 Protein
  • Ptgerep3 Protein
  • Rep3 Protein
  • rEP3a Protein
  • rEP3b Protein

Bezeichner auf Proteinebene für PTGER3

prostaglandin E2 receptor EP3 subtype , prostaglandin E receptor 3, subtype EP3 , prostaglandin E receptor 3 (subtype EP3) , PGE receptor, EP3 subtype , PGE2 receptor EP3 subtype , prostaglandin E receotor EP3 subtype 3 isoform , prostaglandin receptor (PGE-2) , prostanoid EP3 receptor , PGE receptor EP3 subtype , prostaglandin EP3 receptor subtype , prostaglandin E receptor EP3 subtype , prostaglandin E2 receptor EP3B subtype , Prostaglandin E2 receptor EP3 subtype

GENE ID SPEZIES
429116 Gallus gallus
456940 Pan troglodytes
703398 Macaca mulatta
100049776 Xenopus laevis
100053557 Equus caballus
100593534 Nomascus leucogenys
5733 Homo sapiens
100009389 Oryctolagus cuniculus
282330 Bos taurus
24929 Rattus norvegicus
19218 Mus musculus
403430 Canis lupus familiaris
396811 Sus scrofa
443496 Ovis aries
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