Proline-serine-threonine Phosphatase Interacting Protein 2 Proteine (PSTPIP2)

Binds to F-actin. Zusätzlich bieten wir Ihnen Proline-serine-threonine Phosphatase Interacting Protein 2 Antikörper (20) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte PSTPIP2 PSTPIP2 307248  
PSTPIP2 9050 Q9H939
PSTPIP2 19201 Q99M15
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
Details

PSTPIP2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Proline-serine-threonine Phosphatase Interacting Protein 2 (PSTPIP2) Interaktionspartnern

Human Proline-serine-threonine Phosphatase Interacting Protein 2 (PSTPIP2) Interaktionspartner

  1. PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1 (zeige GATA1 Proteine)-deficient megakaryocytes by activating LYN (zeige LYN Proteine).

Mouse (Murine) Proline-serine-threonine Phosphatase Interacting Protein 2 (PSTPIP2) Interaktionspartner

  1. a new PSTPIP1 (zeige PSTPIP1 Proteine)/PTPN6 (zeige PTPN6 Proteine)/SHIP1 (zeige INPP5D Proteine)/2-dependent negative feedback mechanism that counterbalances Src (zeige SRC Proteine) and PI(3,4,5)P3 signalling to control osteoclast cell polarity and activity during bone resorption

  2. SHIP1 (zeige INPP5D Proteine) and Csk (zeige CSK Proteine) are part of the PSTPIP2-dependent inhibitory network that prevents the development of autoinflammatory disease.

  3. PSTPIP2 could play a role in innate immunity and development of autoinflammatory bone disorders, and may be associated with the pathogenesis of SAPHO syndrome.

  4. inflammasome-independent production of IL-1beta (zeige IL1B Proteine) has a critical role in osteolytic bone disease; PSTPIP2 is a negative regulator of caspase-1 (zeige CASP1 Proteine)-autonomous IL-1beta (zeige IL1B Proteine) production

  5. IL-1beta (zeige IL1B Proteine) has a role in mediating autoinflammatory disease in Pstpip2-deficient mice

  6. Knockdown of PSTPIP2 inmacrophages enhances the assembly of FBP17 (zeige FNBP1 Proteine), leading to'hyperactivation' of actin nucleation at podosomes and ECM (zeige MMRN1 Proteine) degradation.

  7. PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts.

  8. our pstpip2 mutant mice provide a new model for investigating the potential mechanisms of inflammatory pain.

  9. MAYP directly regulates F-actin bundling and enhances filopodia formation and motility in macrophages.

  10. A missense mutation in pstpip2 is associated with the autoinflammatory disorder chronic multifocal osteomyelitis.

Proline-serine-threonine Phosphatase Interacting Protein 2 (PSTPIP2) Protein Überblick

Protein Überblick

Binds to F-actin. May be involved in regulation of the actin cytoskeleton.

Genbezeichner und Symbole assoziert mit PSTPIP2

  • proline-serine-threonine phosphatase-interacting protein 2 (Pstpip2)
  • proline-serine-threonine phosphatase interacting protein 2 S homeolog (pstpip2.S)
  • proline-serine-threonine phosphatase interacting protein 2 (PSTPIP2)
  • proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1)
  • proline-serine-threonine phosphatase interacting protein 2 (pstpip2)
  • proline-serine-threonine phosphatase-interacting protein 2 (LOC100136685)
  • cmo Protein
  • DKFZp469B1527 Protein
  • MAYP Protein
  • MGC82175 Protein
  • PSTPIP2 Protein
  • RGD1563090 Protein

Bezeichner auf Proteinebene für PSTPIP2

proline-serine-threonine phosphatase interacting protein 2 , proline-serine-threonine phosphatase-interacting protein 2 , similar to proline-serine-threonine phosphatase interacting protein 1 , proline-serine-threonine phosphatase-interacting protein 2-like , PEST phosphatase-interacting protein 2 , macrophage actin-associated tyrosine-phosphorylated protein , pp37

GENE ID SPEZIES
307248 Rattus norvegicus
446605 Xenopus laevis
480150 Canis lupus familiaris
523223 Bos taurus
708327 Macaca mulatta
737635 Pan troglodytes
770399 Gallus gallus
100135727 Xenopus (Silurana) tropicalis
100136685 Oncorhynchus mykiss
100172267 Pongo abelii
100390433 Callithrix jacchus
100605444 Nomascus leucogenys
9050 Homo sapiens
19201 Mus musculus
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