Premelanosome Protein (PMEL) ELISA Kits

PMEL encodes a melanocyte-specific type I transmembrane glycoprotein. Zusätzlich bieten wir Ihnen PMEL Antikörper (284) und PMEL Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
PMEL 6490 P40967
PMEL 20431  
Anti-Ratte PMEL PMEL 362818  
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Top PMEL ELISA Kits auf

Showing 8 out of 22 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.057 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Maus 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
Schwein 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Kaninchen 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Huhn 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Affe 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Human 18.75 pg/mL 31.25 pg/mL - 2000 pg/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Am meisten referenzierte PMEL ELISA Kits

  1. Human PMEL ELISA Kit für Sandwich ELISA - ABIN414624 : Bande, Santiago, Mera, Piulats, Blanco, Rodríguez-Álvarez, Capeans, Piñeiro, Pardo: ME20-S as a Potential Biomarker for the Evaluation of Uveal Melanoma. in Investigative ophthalmology & visual science 2015 (PubMed)

Weitere ELISA Kits für PMEL Interaktionspartner

Human Premelanosome Protein (PMEL) Interaktionspartner

  1. To provide a source of dual-specific T cells for ACT, we generated a transgenic mouse strain expressing a CAR specific for Her2 (zeige ERBB2 ELISA Kits) in leukocytes under the control of the vav (zeige VAV1 ELISA Kits) promoter .This CAR mouse strain was bred onto the pMEL transgenic mouse strain, expressing a TCR specific for the premelanosome protein, gp100

  2. IMCgp100 (ImmTAC recognizing a peptide derived from the melanoma-specific protein, gp100, presented by HLA-A*0201) efficiently redirects and activates effector and memory cells from both CD8 (zeige CD8A ELISA Kits)(+) and CD4 (zeige CD4 ELISA Kits)(+) repertoires to kill melanoma cells.

  3. our work attempts to provide structural insights into the RPT domain structure and to elucidate its contribution to Pmel17 amyloid fibril formation.

  4. These findings help to clarify the mechanism of T-cell recognition of gp100 during melanoma responses and could direct the development of altered peptides for vaccination.

  5. Data suggest that the Kringle-like domain of PMEL facilitates post-endoplasmic reticulum processing of disulfide-bonded PMEL dimers and promotes formation of PMEL functional amyloid fibrillar structures within multivesicular endosomes.

  6. mutant N-terminally extended peptides exhibited significantly increased HLA-A*02:01 binding affinity and elicited CD8 (zeige CD8A ELISA Kits)(+) T cell stimulation in vitro similar to the wtgp100209-217 epitope.

  7. Data indicate that repeat domain (RPT) derived from Pmel17 aggregation kinetics were influenced only by lysolipid-containing phospholipid vesicles.

  8. Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL expression.

  9. SIL-TAL1 (zeige TAL1 ELISA Kits) rearrangement identifies a distinct subtype with inferior outcome which could allow for individual therapeutic stratification for T-ALL patients.

  10. the molecular basis for the distinct trafficking and morphogenetic properties of PMEL and GPNMB is the PKD (zeige PRKD1 ELISA Kits) domain

Cow (Bovine) Premelanosome Protein (PMEL) Interaktionspartner

  1. Six solid colors occur in Highland cattle: black, dun, silver dun and red, yellow, and white. These six coat colors are explained by a non-epistatic interaction of the genotypes at the MC1R (zeige MSHR ELISA Kits) and PMEL genes.

  2. no convincing recombination events were found between the SILV c.64A>G mutation and the Dc locus

  3. the complex expression pattern of the bovine SILV gene in pigmented and non-pigmented tissues

Mouse (Murine) Premelanosome Protein (PMEL) Interaktionspartner

  1. Prophylactic and therapeutic vaccinations of mice with MCMV-gp100KGP effectively protected mice from highly aggressive lung B16-F10 (zeige F10 ELISA Kits) melanoma, and the protection was mediated by gp100-specific CD8 (zeige CD8A ELISA Kits)(+) T cells

  2. Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL expression.

  3. the BACE1 (zeige BACE ELISA Kits) homologue BACE2 (zeige BACE2 ELISA Kits) processes PMEL to generate functional amyloids

  4. A long-peptide vaccine formulation of 20-mer (zeige ERH ELISA Kits) synthetic peptide elicits gp100-specific CD8 (zeige CD8A ELISA Kits) T cells from the endogenous repertoire.

  5. Despite a mild effect on visible pigmentation, inactivation of Pmel led to a substantial reduction in eumelanin content in hair, which demonstrates that PMEL has a critical role for maintaining efficient epidermal pigmentation.

  6. Pmel17 gene expression is Microphthalmia-associated transcription factor (zeige MITF ELISA Kits)-dependent in the mouse embryo.

  7. These data reveal a dual sorting defect in a natural mutant of Pmel17 and support a requirement of endocytic trafficking in Pmel17 fibril formation.

PMEL Antigen-Profil

Beschreibung des Gens

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit Premelanosome Protein (PMEL) ELISA Kits

  • premelanosome protein (PMEL) Antikörper
  • premelanosome protein (Pmel) Antikörper
  • D10H12S53E Antikörper
  • D12S53E Antikörper
  • D12S53Eh Antikörper
  • gp87 Antikörper
  • gp100 Antikörper
  • ME20 Antikörper
  • ME20-M Antikörper
  • ME20M Antikörper
  • MMP115 Antikörper
  • P1 Antikörper
  • P100 Antikörper
  • Pmel17 Antikörper
  • RPE1 Antikörper
  • Si Antikörper
  • SIL Antikörper
  • Silv Antikörper

Bezeichner auf Proteinebene für Premelanosome Protein (PMEL) ELISA Kits

melanocyte protein PMEL , melanocyte protein Pmel 17 , melanocyte protein mel 17 , melanocytes lineage-specific antigen GP100 , melanoma-associated ME20 antigen , melanosomal matrix protein17 , silver locus protein homolog , silver, mouse, homolog of , silver homolog , retinal pigment epithelial-specific protein , melanocyte protein pmel 17 , silver locus protein , 115 kDa melanosomal matrix protein , PMEL17 protein

6490 Homo sapiens
481102 Canis lupus familiaris
594851 Sus scrofa
281487 Bos taurus
20431 Mus musculus
362818 Rattus norvegicus
396007 Gallus gallus
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