anti-Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Antikörper

The protein encoded by KCNN4 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Zusätzlich bieten wir Ihnen KCNN4 Proteine (3) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KCNN4 3783 O15554
KCNN4 65206  
KCNN4 16534 O89109
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-KCNN4 Antikörper auf antikoerper-online.de

Showing 10 out of 87 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-KCNN4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate Host:  Rabbit  Target Name:  KCNN4  Sample Tissue:  Human Ovary Tumor  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: KCNN4 Antibody [NBP2-33694] - breast cancer Immunohistochemistry: KCNN4 Antibody [NBP2-33694] - Immunohistochemical staining of human smooth muscle shows moderate cytoplasmic positivity in smooth muscle cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Rind (Kuh) Ziege Unkonjugiert IHC, IHC (p) Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p) Anti-KCNN4 antibody  ABIN1048993 IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p) Anti-KCNN4 antibody  ABIN1048992 IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB Anti-KCNN antibody,  Western blotting All lanes: Anti KCNN() at 0.5ug/ml WB: HUT Whole Cell Lysate at 40ug Predicted bind size: 60KD Observed bind size: 60KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB KCNN4 (KCA3.1) Polyclonal Antibody 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$379.50
Details

KCNN4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , , ,
, ,
,
, , , , , , , , , , , , , , ,
Rat (Rattus) , , , ,
, ,
,
, , , , , , , , , , , , , , ,
Mouse (Murine) , , ,
, ,
,
, , , , , , , , , , , , ,

Am meisten referenzierte anti-KCNN4 Antikörper

  1. Human Polyclonal KCNN4 Primary Antibody für WB - ABIN948055 : Wong, Roberts, Randall: Sex differences in endothelial function in porcine coronary arteries: a role for H2O2 and gap junctions? in British journal of pharmacology 2014 (PubMed)

  2. Human Polyclonal KCNN4 Primary Antibody für IF (p), IHC (p) - ABIN719786 : Zhang, Yang, Yin, Yi, Shen, Zhao, Zhu, Liu: Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells. in PLoS ONE 2016 (PubMed)

  3. Human Polyclonal KCNN4 Primary Antibody für IHC, IHC (p) - ABIN4328499 : Rabjerg, Oliván-Viguera, Hansen, Jensen, Sevelsted-Møller, Walter, Jensen, Marcussen, Köhler: High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival. in PLoS ONE 2015 (PubMed)

Weitere Antikörper gegen KCNN4 Interaktionspartner

Pig (Porcine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Interaktionspartner

  1. Blockade of K(Ca)3.1 by delivery of TRAM (zeige TRAM1 Antikörper)-34 via balloon catheter prevented smooth muscle phenotypic modulation and limited subsequent restenosis in a swine model.

Human Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Interaktionspartner

  1. this study reports cryo-electron microscopy (cryo-EM) structures of a human SK4-CaM channel complex in closed and activated states at 3.4- and 3.5-angstrom resolution, respectively.

  2. Expression of intermediate-conductance calmodulin/calcium-activated K+ channels 3.1 (KCa3.1) mRNA and protein was detected in all three layers of the human cornea.

  3. KCa3.1 channels are important modulators in hepatocellular homeostasis.

  4. Tumor suppressor miR (zeige MLXIP Antikörper)-497-5p down-regulates KCa3.1 expression and contributes to the inhibition of angiosarcoma malignancy development.

  5. We identified a two-gene signature including KCNN4 and S100A14 (zeige S100A14 Antikörper) which was related to recurrence in optimally debulked serous ovarian carcinoma patients

  6. Human arrhythmogenic calmodulin mutations impede the activation of SK2 (zeige KCNN2 Antikörper) channels in human embryonic kidney 293 cells.

  7. This study found a very substantial functional expression of KCa3.1 channels in microglia from adult epilepsy patients.

  8. Data show that RNAi-mediated knockdown of KCa3.1 and/or TRPC1 (zeige TRPC1 Antikörper) leads to a significant decrease in cell proliferation due to cell cycle arrest in the G1 phase.

  9. Higher epithelial KCNN4 expression was closely correlated with advanced TNM (zeige ODZ1 Antikörper) stages and predicted a poor prognosis in patients with pancreatic ductal adenocarcinoma.

  10. Here, the authors demonstrate that phosphorylation of His358 activates KCa3.1 by antagonizing copper-mediated inhibition of the channel.

Cow (Bovine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Interaktionspartner

  1. Blood brain barrier endothelial cells exhibit KCa3.1 protein and activity.

Mouse (Murine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Interaktionspartner

  1. Diet-induced hyperhomocysteinemia enhanced myoendothelial feedback, and increased Cx37 (zeige GJA4 Antikörper) and IK1 expression may contribute. nNOS (zeige NOS1 Antikörper) or iNOS (zeige NOS2 Antikörper) did not upregulate to compensate for decreased eNOS (zeige NOS3 Antikörper), and they had little involvement in vasomotor function.

  2. The Intermediate-conductance calmodulin/calcium-activated K+ channels 3.1 (KCa3.1-/- knockout mice) significantly reduced corneal fibrosis and expression of pro-fibrotic marker genes, suggesting that KCa3.1 plays an important role corneal wound healing in vivo.

  3. KCa3.1(-/-) mice exhibited significantly smaller infarct areas in a model of ischemic stroke.

  4. KCa3.1(-/-) mice demonstrated normal behavioral responses in models of acute nociceptive, persistent inflammatory, and persistent neuropathic pain. However, their behavioral responses to noxious chemical stimuli such as formalin and capsaicin were increased. Accordingly, formalin-induced nociceptive behavior was increased in wild-type mice after administration of the KCa3.1 inhibitor TRAM (zeige TICAM2 Antikörper)-34.

  5. SK4 activity is crucial for cell cycle control.

  6. Following differentiation with LPS (zeige TLR4 Antikörper) or a combination of LPS (zeige TLR4 Antikörper) and IFN-gamma (zeige IFNG Antikörper) microglia exhibited high KV 1.3 current densities ( approximately 50 pA/pF at 40 mV) and virtually no KCa (zeige CSN3 Antikörper) 3.1 and Kir (zeige GEM Antikörper) currents, while microglia differentiated with IL-4 (zeige IL4 Antikörper) exhibited large Kir (zeige GEM Antikörper) 2.1 currents ( approximately 10 pA/pF at -120 mV). KCa (zeige CSN3 Antikörper) 3.1 currents were generally low

  7. Deletion of KCa3.1 reduced astrogliosis and rescued memory loss induced by intrahippocampal Abeta1-42 peptide injection.

  8. Dynamic coupling between TRPV4 (zeige TRPV4 Antikörper) and Ca(2 (zeige CA2 Antikörper)+)-activated SK1 (zeige SPHK1 Antikörper)/3 and IK1 K(+) channels plays a critical role in regulating the K(+)-secretory BK channel KCNMA1 (zeige KCNMA1 Antikörper) in kidney collecting duct cells.

  9. Blocking KCa3.1 suppresses plaque instability in advanced stages of atherosclerosis by inhibiting macrophage polarization toward an M1 phenotype.

  10. enhanced KCa (zeige CSN3 Antikörper) 3.1 activity may compensate for decreased nitric oxide signaling during vascular aging.

KCNN4 Antigen-Profil

Protein Überblick

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

Genbezeichner und Symbole assoziert mit KCNN4

  • potassium calcium-activated channel subfamily N member 4 (KCNN4) Antikörper
  • potassium calcium-activated channel subfamily N member 4 (Kcnn4) Antikörper
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (Kcnn4) Antikörper
  • hIKCa1 Antikörper
  • hKCa4 Antikörper
  • hSK4 Antikörper
  • IK1 Antikörper
  • IKCA1 Antikörper
  • KCa3.1 Antikörper
  • KCA4 Antikörper
  • mIKCa1 Antikörper
  • rKCNN4c Antikörper
  • rSK4 Antikörper
  • SK4 Antikörper
  • SKCas Antikörper

Bezeichner auf Proteinebene für KCNN4

intermediate conductance calcium-activated potassium channel protein 4 , intermediate-conductance calcium-activated potassium channel , intermediate conductance calcium-activated potassium channel protein 1 , potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 , intermediate conductance calcium-activated potassium channel protein 4-like , SKCa 4 , SKCa4 , putative Gardos channel , putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel , IK1 , KCa4 , SK4 , intermediate conductance K channel , intermediate-conductance Ca-activated K channel , potassium intermediate-small conductance calcium-activated channel subfamily N member 4

GENE ID SPEZIES
397081 Sus scrofa
456098 Pan troglodytes
100379254 Cavia porcellus
100391934 Callithrix jacchus
100468357 Ailuropoda melanoleuca
100593199 Nomascus leucogenys
3783 Homo sapiens
65206 Rattus norvegicus
534591 Bos taurus
484464 Canis lupus familiaris
16534 Mus musculus
Ausgewählte Anbieter für anti-KCNN4 (KCNN4) Antikörper
Haben Sie etwas anderes gesucht?