anti-Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Antikörper

The protein encoded by KCNN4 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Zusätzlich bieten wir Ihnen KCNN4 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KCNN4 3783 O15554
KCNN4 65206  
KCNN4 16534 O89109
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Top anti-KCNN4 Antikörper auf antikoerper-online.de

Showing 10 out of 79 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-KCNN4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: KCNN4 Antibody [NBP2-33694] - breast cancer Immunohistochemistry: KCNN4 Antibody [NBP2-33694] - Immunohistochemical staining of human smooth muscle shows moderate cytoplasmic positivity in smooth muscle cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Anti-KCNN4 antibody  ABIN1048992 IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC (p) Anti-KCNN4 antibody  ABIN1048993 IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Rind (Kuh) Ziege Unkonjugiert IHC (p) Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB Anti-KCNN antibody,  Western blotting All lanes: Anti KCNN() at 0.5ug/ml WB: HUT Whole Cell Lysate at 40ug Predicted bind size: 60KD Observed bind size: 60KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB KCNN4 (KCA3.1) Polyclonal Antibody 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$379.50
Details

KCNN4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-KCNN4 Antikörper

  1. Human Polyclonal KCNN4 Primary Antibody für WB - ABIN948055 : Wong, Roberts, Randall: Sex differences in endothelial function in porcine coronary arteries: a role for H2O2 and gap junctions? in British journal of pharmacology 2014 (PubMed)

  2. Human Polyclonal KCNN4 Primary Antibody für IF (p), IHC (p) - ABIN719786 : Zhang, Yang, Yin, Yi, Shen, Zhao, Zhu, Liu: Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells. in PLoS ONE 2016 (PubMed)

  3. Human Polyclonal KCNN4 Primary Antibody für IHC, IHC (p) - ABIN4328499 : Rabjerg, Oliván-Viguera, Hansen, Jensen, Sevelsted-Møller, Walter, Jensen, Marcussen, Köhler: High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival. in PLoS ONE 2015 (PubMed)

Weitere Antikörper gegen KCNN4 Interaktionspartner

Pig (Porcine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Interaktionspartner

  1. Blockade of K(Ca)3.1 by delivery of TRAM (zeige TRAM1 Antikörper)-34 via balloon catheter prevented smooth muscle phenotypic modulation and limited subsequent restenosis in a swine model.

Human Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Interaktionspartner

  1. Tumor suppressor miR (zeige MLXIP Antikörper)-497-5p down-regulates KCa3.1 expression and contributes to the inhibition of angiosarcoma malignancy development.

  2. We identified a two-gene signature including KCNN4 and S100A14 (zeige S100A14 Antikörper) which was related to recurrence in optimally debulked serous ovarian carcinoma patients

  3. Human arrhythmogenic calmodulin mutations impede the activation of SK2 (zeige KCNN2 Antikörper) channels in human embryonic kidney 293 cells.

  4. This study found a very substantial functional expression of KCa3.1 channels in microglia from adult epilepsy patients.

  5. Data show that RNAi-mediated knockdown of KCa3.1 and/or TRPC1 (zeige TRPC1 Antikörper) leads to a significant decrease in cell proliferation due to cell cycle arrest in the G1 phase.

  6. Higher epithelial KCNN4 expression was closely correlated with advanced TNM (zeige ODZ1 Antikörper) stages and predicted a poor prognosis in patients with pancreatic ductal adenocarcinoma.

  7. Here, the authors demonstrate that phosphorylation of His358 activates KCa3.1 by antagonizing copper-mediated inhibition of the channel.

  8. This work demonstrates the critical role of SK4 Ca(2 (zeige CA2 Antikörper)+)-activated K(+) channels in adult pacemaker function.

  9. Implicating both KCa1.1 (zeige KCNMA1 Antikörper) and KCa3.1 channels.

  10. Blocking KCa3.1 suppresses plaque instability in advanced stages of atherosclerosis by inhibiting macrophage polarization toward an M1 phenotype.

Cow (Bovine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Interaktionspartner

  1. Blood brain barrier endothelial cells exhibit KCa3.1 protein and activity.

Mouse (Murine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Interaktionspartner

  1. Following differentiation with LPS (zeige TLR4 Antikörper) or a combination of LPS (zeige TLR4 Antikörper) and IFN-gamma (zeige IFNG Antikörper) microglia exhibited high KV 1.3 current densities ( approximately 50 pA/pF at 40 mV) and virtually no KCa (zeige CSN3 Antikörper) 3.1 and Kir (zeige GEM Antikörper) currents, while microglia differentiated with IL-4 (zeige IL4 Antikörper) exhibited large Kir (zeige GEM Antikörper) 2.1 currents ( approximately 10 pA/pF at -120 mV). KCa (zeige CSN3 Antikörper) 3.1 currents were generally low

  2. Deletion of KCa3.1 reduced astrogliosis and rescued memory loss induced by intrahippocampal Abeta1-42 peptide injection.

  3. Dynamic coupling between TRPV4 (zeige TRPV4 Antikörper) and Ca(2 (zeige CA2 Antikörper)+)-activated SK1 (zeige SPHK1 Antikörper)/3 and IK1 K(+) channels plays a critical role in regulating the K(+)-secretory BK channel KCNMA1 (zeige KCNMA1 Antikörper) in kidney collecting duct cells.

  4. Blocking KCa3.1 suppresses plaque instability in advanced stages of atherosclerosis by inhibiting macrophage polarization toward an M1 phenotype.

  5. enhanced KCa (zeige CSN3 Antikörper) 3.1 activity may compensate for decreased nitric oxide signaling during vascular aging.

  6. Findings highlight a novel role for intermediate-conductance calcium-activated potassium channel (zeige KCNAB2 Antikörper) (KCa3.1) in phenotypic modulation of reactive astrocytes and in astrocyte mobilization in response to mechanical stress, providing a potential target for therapeutic intervention in brain injuries.

  7. alpha1D Ca and SK4 channels are coupled in the atria, and deletion of alpha1D leads to decreased SK4 mRNA and BNP (zeige BNC2 Antikörper) secretion providing evidence for a novel role of alpha1D in atrial endocrine function

  8. KCa3.1 blockade protects against cisplatin-induced acute kidney injury through the attenuation of apoptosis by interference with intrinsic apoptotic and endoplasmic reticulum stress-related mediators.

  9. The results suggest that KCa3.1 activation contributes to dysfunctional tubular autophagy in diabetic nephropathy through PI3K/Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) signaling pathways.

  10. These results indicate that IK1 channels do not mediate the a slow afterhyperpolarization in pyramidal neurons.

KCNN4 Antigen-Profil

Protein Überblick

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

Genbezeichner und Symbole assoziert mit KCNN4

  • potassium calcium-activated channel subfamily N member 4 (KCNN4) Antikörper
  • potassium calcium-activated channel subfamily N member 4 (Kcnn4) Antikörper
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (Kcnn4) Antikörper
  • hIKCa1 Antikörper
  • hKCa4 Antikörper
  • hSK4 Antikörper
  • IK1 Antikörper
  • IKCA1 Antikörper
  • KCa3.1 Antikörper
  • KCA4 Antikörper
  • mIKCa1 Antikörper
  • rKCNN4c Antikörper
  • rSK4 Antikörper
  • SK4 Antikörper
  • SKCas Antikörper

Bezeichner auf Proteinebene für KCNN4

intermediate conductance calcium-activated potassium channel protein 4 , intermediate-conductance calcium-activated potassium channel , intermediate conductance calcium-activated potassium channel protein 1 , potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 , intermediate conductance calcium-activated potassium channel protein 4-like , SKCa 4 , SKCa4 , putative Gardos channel , putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel , IK1 , KCa4 , SK4 , intermediate conductance K channel , intermediate-conductance Ca-activated K channel , potassium intermediate-small conductance calcium-activated channel subfamily N member 4

GENE ID SPEZIES
397081 Sus scrofa
456098 Pan troglodytes
100379254 Cavia porcellus
100391934 Callithrix jacchus
100468357 Ailuropoda melanoleuca
100593199 Nomascus leucogenys
3783 Homo sapiens
65206 Rattus norvegicus
534591 Bos taurus
484464 Canis lupus familiaris
16534 Mus musculus
Ausgewählte Anbieter für anti-KCNN4 (KCNN4) Antikörper
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