Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) Proteine (POLR3C)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Zusätzlich bieten wir Ihnen POLR3C Antikörper (72) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
POLR3C 74414 Q9D483
Ratte POLR3C POLR3C 310685 Q5XIL3
POLR3C 10623 Q9BUI4
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Top POLR3C Proteine auf antikoerper-online.de

Showing 5 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Escherichia coli (E. coli) Human His-SUMO Tag 100 μg Anmelden zum Anzeigen 11 Days
$411.40
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details

POLR3C Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , , ,
, , ,

Weitere Proteine zu Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) Interaktionspartnern

Human Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) Interaktionspartner

  1. monogenic or digenic POLR3A (zeige POLR3A Proteine) and POLR3C deficiencies confer increased susceptibility to severe VZV disease in otherwise healthy children, providing evidence for an essential role of a DNA sensor in human immunity

  2. The study reports the crystal structure of RPC62.

POLR3C Protein Überblick

Protein Überblick

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB- DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

Genbezeichner und Symbole assoziert mit POLR3C

  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog (polr3c.S)
  • RNA polymerase III subunit C (POLR3C)
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C)
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) (polr3c)
  • polymerase (RNA) III (DNA directed) polypeptide C (Polr3c)
  • RNA polymerase III subunit C (Polr3c)
  • polymerase (RNA) III (DNA directed) polypeptide C (polr3c)
  • 4933407E01Rik Protein
  • RPC3 Protein
  • RPC62 Protein
  • zgc:56348 Protein

Bezeichner auf Proteinebene für POLR3C

polymerase (RNA) III (DNA directed) polypeptide C (62kD) , DNA-directed RNA polymerase III subunit RPC3-like , DNA-directed RNA polymerase III subunit C , DNA-directed RNA polymerase III subunit RPC3 , RNA polymerase III subunit C3 , DNA-directed III 62 kDa polypeptide , RNA polymerase III 62 kDa subunit

GENE ID SPEZIES
446308 Xenopus laevis
457224 Pan troglodytes
483159 Canis lupus familiaris
776505 Gallus gallus
100014746 Monodelphis domestica
100341275 Oryctolagus cuniculus
100380066 Xenopus (Silurana) tropicalis
100401836 Callithrix jacchus
100431311 Pongo abelii
100589512 Nomascus leucogenys
74414 Mus musculus
310685 Rattus norvegicus
393201 Danio rerio
10623 Homo sapiens
507314 Bos taurus
Ausgewählte Anbieter für POLR3C Proteine (POLR3C)
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