anti-Poly(rC) Binding Protein 2 (PCBP2) Antikörper

The protein encoded by PCBP2 appears to be multifunctional. Zusätzlich bieten wir Ihnen PCBP2 Proteine (9) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PCBP2 5094 Q15366
PCBP2 18521 Q61990
PCBP2 363005  
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Top anti-PCBP2 Antikörper auf antikoerper-online.de

Showing 10 out of 63 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-PCBP2 Antibody Titration: 1.25ug/ml Positive Control: Jurkat cell lysate There is BioGPS gene expression data showing that PCBP2 is expressed in Jurkat Rabbit Anti-PCBP2 Antibody Paraffin Embedded Tissue: Human Lung Cellular Data: Alveolar cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$249.00
Details
Human Maus Unkonjugiert IF, IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to PCBP2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, IF, IHC, WB Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell (antibody concentration 10 µg/mL). Western blot analysis of PCBP2 over-expressed 293 cell line, cotransfected with PCBP2 Validated Chimera RNAi used as specificity and loading control. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PCBP2 Antibody Titration: 2.5ug/ml Positive Control: HepG2 cell lysate PCBP2 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cell lines, using PCBP2 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.77
Details
Human Kaninchen Unkonjugiert ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PCBP2, antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 10% SDS PAGE antibody diluted at 1:500 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry: PCBP2 Antibody [NBP1-83241] - Immunofluorescence: [NBP1-83241] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: PCBP2 Antibody [NBP1-83241] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of hnRNP E2 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibo 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details

Am meisten referenzierte anti-PCBP2 Antikörper

  1. Human Monoclonal PCBP2 Primary Antibody für IF, IHC (p) - ABIN562121 : Fujimura, Kano, Murata: Identification of PCBP2, a facilitator of IRES-mediated translation, as a novel constituent of stress granules and processing bodies. in RNA (New York, N.Y.) 2008 (PubMed)
    Show all 9 Pubmed References

  2. Cow (Bovine) Polyclonal PCBP2 Primary Antibody für IHC, WB - ABIN2778923 : Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal PCBP2 Primary Antibody für ELISA, WB - ABIN394008 : Kim, Chang, Yun, Yang, Hong, Kim, Um, Lee, Lee, Hwang: Chloride intracellular channel 1 identified using proteomic analysis plays an important role in the radiosensitivity of HEp-2 cells via reactive oxygen species production. in Proteomics 2010 (PubMed)

  4. Human Polyclonal PCBP2 Primary Antibody für ICC, IF - ABIN4344023 : Flynn, Martin, Spitale, Do, Sagan, Zarnegar, Qu, Khavari, Quake, Sarnow, Chang: Dissecting noncoding and pathogen RNA-protein interactomes. in RNA (New York, N.Y.) 2014 (PubMed)

Weitere Antikörper gegen PCBP2 Interaktionspartner

Human Poly(rC) Binding Protein 2 (PCBP2) Interaktionspartner

  1. PCBP2 expression was markedly increased in higher stages of glioblastoma compared with those in lower stages; further research suggested that PCBP2 upregulation was connected with poorer prognosis in patients with glioblastoma

  2. Double immunofluorescence for hnRNP E2 and TDP-43 (zeige TARDBP Antikörper) showed most TDP-43 (zeige TARDBP Antikörper) immunopositive dystrophic neuritis within frontal and temporal cortex, and the neuronal cytoplasmic inclusions seen in dentate gyrus granule cells, to contain hnRNP E2. Present findings indicate an association between TDP-43 (zeige TARDBP Antikörper) and hnRNP E2 which might underlie the pathogenetic mechanism of Semantic Dementia Frontotemporal Lobar Degeneration.

  3. Data suggest that the interaction between PCBP2 and the 3'UTR (zeige UTS2R Antikörper) of the ARHGDIA (zeige ARHGDIA Antikörper) mRNA may induce a local change in RNA structure that favors subsequent binding of miR (zeige MLXIP Antikörper)-151-5p and miR-16 (zeige GDE1 Antikörper), thus leading to the suppression of ARHGDIA (zeige ARHGDIA Antikörper) expression.

  4. To promote intracellular iron flux, an iron chaperone appears to be essential for receiving iron from heme catabolism. Data suggest that PCBP2 competes with CPR (zeige POR Antikörper) for binding HO1 (zeige HMOX1 Antikörper); PCBP2 K homology 3 domain is important for HO1 (zeige HMOX1 Antikörper)/PCBP2 interaction; heme prompts HO1 (zeige HMOX1 Antikörper)/CPR (zeige POR Antikörper) multimer and decreases HO1 (zeige HMOX1 Antikörper)/PCBP2 multimer. [PCBP2 = poly(rC) binding protein 2; CPR (zeige POR Antikörper) = cytochrome P450 reductase (zeige POR Antikörper); HO1 (zeige HMOX1 Antikörper) = heme oxidase 1]

  5. BC200 RNA interacts with hnRNP E1 (zeige PCBP1 Antikörper) and E2 mainly through its unique 3' C-rich domain.

  6. Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.

  7. These results suggest that FPN1 (zeige SLC40A1 Antikörper) exports iron received from the iron chaperone PCBP2. Therefore, it was found that PCBP2 modulates cellular iron export, which is an important physiological process.

  8. PCBP2 was overexpressed in esophageal squamous cell carcinoma tissues and cell lines. PCBP2 expression promoted proliferation of ESCC cells. We also found that reduced PCBP2 expression might induce ESCC cell apoptosis with increased cleaved caspase3 expression. Overall, our findings indicated that PCBP2 might be involved in the ESCC progression and be considered as a new treatment target in ESCC.

  9. High expression of PCBP2 may contribute to sorafenib resistance in hepatocellular carcinoma cells.

  10. our data indicate that miR (zeige MLXIP Antikörper)-214 may function as tumor suppressor in glioma by targeting PCBP2

Mouse (Murine) Poly(rC) Binding Protein 2 (PCBP2) Interaktionspartner

  1. Study determined that PCBP2 specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.

  2. data suggest that PCBP2 regulates p73 (zeige ARHGAP24 Antikörper) expression via mRNA stability and p73 (zeige ARHGAP24 Antikörper)-dependent biological function in ROS (zeige ROS1 Antikörper) production and cellular senescence.

  3. PCBP2 overexpression rescues the Meis1 (zeige MEIS1 Antikörper) effects of Akt (zeige AKT1 Antikörper)-mTOR (zeige FRAP1 Antikörper) pathway and hypertrophy of cardiomyocytes.

  4. These data reveal that Pcbp1 (zeige PCBP1 Antikörper) and Pcbp2 are individually essential for mouse embryonic development and have distinct impacts on embryonic viability and that Pcpb2 has a nonredundant in vivo role in hematopoiesis.

  5. PCBP2 knockdown promoted angiotensin II-induced hypertrophy (increase in cell size, protein synthesis and activation of fetal genes) of cardiomyocytes, while PCBP2 overexpression obtained oppose effects.

  6. Our analysis of PCBP1 (zeige PCBP1 Antikörper) and PCBP2 expression demonstrates robust expression of these two proteins within the gastric epithelium with high concordance for both proteins in their cell-type specificities and intracellular distributions.

  7. This study demonstrates for the first time that alpha-CP2 functions as a transcriptional activator by binding to a single-stranded poly(C) sequence.

  8. This study provides evidence that PCBP2 and hnRNP A1 (zeige HNRNPA1 Antikörper) bind to the 5' and 3' ends of the murine norovirus 1 viral RNA and contribute to RNA circularization, playing a role in the virus life cycle.

  9. PCBP2-AIP4 (zeige ITCH Antikörper) axis defines a new signaling cascade for MAVS (zeige MAVS Antikörper) degradation and 'fine tuning' of antiviral innate immunity.

Pig (Porcine) Poly(rC) Binding Protein 2 (PCBP2) Interaktionspartner

  1. These results indicated that Nsp1beta of porcine reproductive and respiratory syndrome virus is able to bind and interact with cellular PCBP2 strongly in both the infected cells and plasmid transfected cells.

  2. Overall, the results presented here point toward an important role for PCBP1 (zeige PCBP1 Antikörper) and PCBP2 in regulating porcine reproductive and respiratory syndrome virus RNA synthesis via binding to viral nonstructural protein 1beta.

PCBP2 Antigen-Profil

Protein Überblick

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PCBP2

  • poly(rC) binding protein 2 (PCBP2) Antikörper
  • poly(rC) binding protein 2 (Pcbp2) Antikörper
  • poly(rC) binding protein 2 (pcbp2) Antikörper
  • poly(rC) binding protein 2 L homeolog (pcbp2.L) Antikörper
  • alphaCP-2 Antikörper
  • AW412548 Antikörper
  • fb36h02 Antikörper
  • hnRNP-E2 Antikörper
  • HNRNPE2 Antikörper
  • HNRPE2 Antikörper
  • Hnrpx Antikörper
  • PCBP2 Antikörper
  • PCBP3 Antikörper
  • wu:fb36h02 Antikörper
  • zgc:55964 Antikörper

Bezeichner auf Proteinebene für PCBP2

alpha-CP2 , heterogeneous nuclear ribonucleoprotein E2 , heterogenous nuclear ribonucleoprotein E2 , hnRNP E2 , poly(rC)-binding protein 2 , CBP , CTBP , heterogeneous nuclear ribonucleoprotein X , hnRNP X , putative heterogeneous nuclear ribonucleoprotein X , poly(rC) binding protein 2 , poly(rC) binding protein 3 , PolyrC-binding protein 2 , poly(rc)-binding protein 2 , heterogeneous nuclear ribonucleoprotein

GENE ID SPEZIES
5094 Homo sapiens
18521 Mus musculus
321844 Danio rerio
363005 Rattus norvegicus
399399 Xenopus laevis
420965 Gallus gallus
477596 Canis lupus familiaris
540653 Bos taurus
733863 Xenopus (Silurana) tropicalis
100194880 Salmo salar
100528911 Ictalurus punctatus
397665 Sus scrofa
100731593 Cavia porcellus
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