Phosducin-Like Proteine (PDCL)

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. Zusätzlich bieten wir Ihnen Phosducin-Like Antikörper (47) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PDCL 5082 Q13371
Ratte PDCL PDCL 64013 Q63737
PDCL 67466 Q9DBX2
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top Phosducin-Like Proteine auf antikoerper-online.de

Showing 6 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His tag 20 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,795.83
Details

PDCL Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Weitere Proteine zu Phosducin-Like (PDCL) Interaktionspartnern

Human Phosducin-Like (PDCL) Interaktionspartner

  1. PhLP1 binding stabilizes the Gbeta (zeige SUCLG2 Proteine) fold, disrupting interactions with CCT (zeige FLVCR2 Proteine) and releasing a PhLP1-Gbeta (zeige SUCLG2 Proteine) dimer for assembly with Ggamma.

  2. evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins.

  3. physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 (zeige CSNK2A1 Proteine) and alternative splicing of the regulator

  4. the strong inhibitory action of PhLP(S) on Gbetagamma signaling is the result of a previously unrecognized mechanism of Gbetagamma-regulation, inhibition of Gbetagamma-folding by interference with TCP-1alpha (zeige TCP1 Proteine)

  5. PhLP phosphorylation permits the release of a PhLP x Gbeta (zeige SUCLG2 Proteine) intermediate from cytosolic chaperonin (zeige HSPD1 Proteine) complex, allowing Ggamma to associate with Gbeta (zeige SUCLG2 Proteine) in this intermediate complex.

  6. cytosolic chaperonin complex-dependent mechanism exists for Gbeta5-RGS7 assembly that utilizes the co-chaperone activity of PhLP1 in a unique way

  7. PhLP-M1-G149, a Gbetagamma-interacting construct derived from phosducin-like protein 1 (PhLP) is a differential inhibitor of Gbetagamma

Mouse (Murine) Phosducin-Like (PDCL) Interaktionspartner

  1. Pdcl has been implicated as a positive regulator of Hedgehog (zeige SHH Proteine) signaling that may control the trafficking of signaling receptors to primary cilia.

  2. findings reveal a common mechanism of Gbetagamma and RGS9-Gbeta5 assembly in rods and cones, highlighting the importance of PhLP1 and CCT-mediated Gbeta complex formation in G protein signaling.

  3. evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins.

  4. this study demonstrated in vivo that PhLP1 is required for the folding and assembly of both Gbetagamma and Gbeta5 (zeige GNB5 Proteine)-RGS9 (zeige RGS Proteine).

  5. These data are consistent with the hypothesis that PhLP is a widely expressed modulator of Gbetagamma function.

  6. These results suggest a mechanism for Gbetagamma assembly in which PhLP stabilizes the nascent Gbeta (zeige SUCLG2 Proteine) polypeptide until Ggamma can associate, resulting in membrane binding of Gbetagamma and release of PhLP to catalyze another round of assembly.

  7. N-glycosylated phosducin-like protein long (PhLP(L)) is expressed in all structures of the central nervous system and regulates opioid receptor function in the brain.

  8. identification of novel germ-like specific form in phosducin-like protein family

  9. physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 (zeige CSNK2A1 Proteine) and alternative splicing of the regulator

Cow (Bovine) Phosducin-Like (PDCL) Interaktionspartner

  1. antagonistic actions of PhLP3 and prefoldin serve to modulate CCT activity and play a key role in establishing a functional cytoskeleton in vivo

Phosducin-Like (PDCL) Protein Überblick

Protein Überblick

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins.

Genbezeichner und Symbole assoziert mit Phosducin-Like Proteine (PDCL)

  • phosducin like (PDCL)
  • phosducin-like (Pdcl)
  • phosducin like (pdcl)
  • phosducin-like (pdcl)
  • 1200011E13Rik Protein
  • AW108059 Protein
  • fc06a08 Protein
  • im:6793474 Protein
  • Phlp Protein
  • PhLP1 Protein
  • wu:fc06a08 Protein
  • zgc:73264 Protein

Bezeichner auf Proteinebene für Phosducin-Like Proteine (PDCL)

phosducin-like protein , PHLP , phosducin-like

GENE ID SPEZIES
5082 Homo sapiens
64013 Rattus norvegicus
67466 Mus musculus
548824 Xenopus (Silurana) tropicalis
286773 Bos taurus
323645 Danio rerio
Ausgewählte Anbieter für Phosducin-Like Proteine (PDCL)
Haben Sie etwas anderes gesucht?