Pescadillo Ribosomal Biogenesis Factor 1 Proteine (PES1)

PES1 encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. Zusätzlich bieten wir Ihnen PES1 Antikörper (42) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PES1 23481 O00541
PES1 64934 Q9EQ61
PES1 289740 Q3B8N8
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Wheat germ Human GST tag 10 μg 11 bis 12 Tage
$414.29
Details
Hefe Ratte His tag   1 mg 60 bis 71 Tage
$3,685.00
Details

PES1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Pescadillo Ribosomal Biogenesis Factor 1 (PES1) Interaktionspartnern

Human Pescadillo Ribosomal Biogenesis Factor 1 (PES1) Interaktionspartner

  1. PES1 is transcriptionally regulated by BRD4 and promotes cell proliferation and glycolysis in hepatocellular carcinoma

  2. upregulated in hepatocellular carcinoma tissues and cells, potentially representing a novel prognostic marker for overall survival

  3. posttranslational modification of PES1 by SUMOylation may serve as a key factor that regulates the function of PES1 in vivo

  4. PES1 may play an important role in development of gastric cancer.

  5. The DDX27 can interact specifically with the Pes1 and Bop1 but fulfils critical function(s) for proper 3' end formation of 47S rRNA independently of the PeBoW-complex.

  6. PES1 may play important role in the progression of ovarian cancer by inversely regulating the ERalpha and ERbeta expression.

  7. these results uncover a potential role of PES1 in chemoresistance by regulating DNA damage response in colorectal cancer cells.

  8. Upstream of c-Jun, it was revealed that c-Jun NH2-terminal kinases (JNK) is essential for controlling PES1 expression

  9. expression of PES1 correlated positively with ERalpha expression and negatively with ERbeta expression and predicted good clinical outcome in breast cancer

  10. The physical interaction between B23 and PES1 implies that they may participate in ribosome biogenesis in a protein complex.

  11. pescadillo might play a role in promoting the proliferation and carcinogenesis of human breast cancer, and thereby might be a potential target for human breast cancer treatment.

  12. Mechanisms for the ability of Pes1 to transform cells, and its failure to immortalize them.

  13. RRB1 interacts with YPH1 (yeast pescadillo homologue 1) and other members of the Yph1 complex

  14. Pes1 and Bop1 form a stable complex with a novel member, WDR12 (PeBoW complex).

  15. Results describe the role of PeBoW-specific proteins Pes1, Bop1, and WDR12 in complex assembly and stability, nucleolar transport, and pre-ribosome association.

Mouse (Murine) Pescadillo Ribosomal Biogenesis Factor 1 (PES1) Interaktionspartner

  1. These data suggest that PES1 is a marker of neuroblastoma outcome, that it regulates neuroblastoma cell proliferation, and is associated with neuroblastoma differentiation.

  2. Data show that pescadillo associates with several structures that are associated with nucleogenesis, and that loss of function results in embryonic lethality due to disrupted ribosome biosynthesis.

  3. effects of PES1 and UBF1 expression on the growth and differentiation of cell lines derived from 32D cells, an interleukin-3 (IL-3)-dependent murine myeloid cell line

  4. Interaction with Bop1 is essential for the efficient incorporation of Pes1 into nucleolar preribosomal complexes.

  5. Mechanisms for the ability of Pes1 to transform cells, and its failure to immortalize them.

  6. Mtap1b-Light chain 1 has the potential to repress cell proliferation by modulating the nucleolar levels of Pes1

Xenopus laevis Pescadillo Ribosomal Biogenesis Factor 1 (PES1) Interaktionspartner

  1. pes1 and ppan are required for Xenopus pronephros development and indicate that their function in the pronephros is independent of their role in ribosome biosynthesis

  2. pescadillo has multiple important functions during X. laevis development; pescadillo is required for eye development and neural crest migration

PES1 Protein Überblick

Protein Überblick

This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.

Genbezeichner und Symbole assoziert mit PES1

  • pescadillo ribosomal biogenesis factor 1 (PES1)
  • pescadillo ribosomal biogenesis factor 1 (Pes1)
  • pescadillo ribosomal biogenesis factor 1 S homeolog (pes1.S)
  • Pescadillo (pesc)
  • pes Protein
  • pes1 Protein

Bezeichner auf Proteinebene für PES1

pescadillo homolog , pescadillo homolog 1, containing BRCT domain

GENE ID SPEZIES
23481 Homo sapiens
64934 Mus musculus
380249 Xenopus laevis
100194837 Salmo salar
289740 Rattus norvegicus
486354 Canis lupus familiaris
511676 Bos taurus
100154050 Sus scrofa
100735041 Cavia porcellus
100354890 Oryctolagus cuniculus
100058627 Equus caballus
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