Peroxisomal Biogenesis Factor 19 Proteine (PEX19)

PEX19 is necessary for early peroxisomal biogenesis. Zusätzlich bieten wir Ihnen PEX19 Antikörper (117) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PEX19 5824 P40855
PEX19 19298 Q8VCI5
PEX19 289233  
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Top PEX19 Proteine auf antikoerper-online.de

Showing 10 out of 17 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Human Unkonjugiert 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$653.13
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$320.00
Details
Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$496.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human Unkonjugiert SDS-PAGE analysis of Human PEX19 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$369.55
Details
Escherichia coli (E. coli) Maus Unkonjugiert SDS-PAGE analysis of Mouse PEX19 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$497.47
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
Details

PEX19 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Peroxisomal Biogenesis Factor 19 (PEX19) Interaktionspartnern

Human Peroxisomal Biogenesis Factor 19 (PEX19) Interaktionspartner

  1. that newly synthesized UBXD8 (zeige FAF2 Proteine) is post-translationally inserted into discrete ER subdomains by a mechanism requiring cytosolic PEX19 and membrane-integrated PEX3 (zeige PEX3 Proteine), proteins hitherto exclusively implicated in peroxisome biogenesis

  2. Thus within the cell, PEX3 (zeige PEX3 Proteine) is stabilized by PEX19 preventing PEX3 (zeige PEX3 Proteine) aggregation.

  3. PEX19 formed a complex with the peroxisomal tail anchored protein PEX26 (zeige PEX26 Proteine) in the cytosol and translocated it directly to peroxisomes by a TRC40 (zeige ASNA1 Proteine)-independent class I pathway.

  4. PEX3 (zeige PEX3 Proteine)-PEX19 interaction is crucial for de novo formation of peroxisomes in peroxisome-deficient cells.

  5. The crystal structure of the cytosolic domain of PEX3 (zeige PEX3 Proteine) in complex with a PEX19-derived peptide. PEX3 (zeige PEX3 Proteine) adopts a novel fold that is best described as a large helical bundle.

  6. a considerable functional diversity of the proteins encoded by two PEX19 splice variants and thereby provide first experimental evidence for specific biological functions of the different predicted domains of the PEX19 protein.

  7. PEX19 binds and stabilizes newly synthesized PMPs in the cytosol, binds to multiple PMP targeting signals (mPTSs), interacts with the hydrophobic domains of PMP targeting signals, and is essential for PMP targeting and import.

  8. Interaction of PEX3 (zeige PEX3 Proteine) and PEX19 visualized by fluorescence resonance energy transfer (FRET).

  9. Pex19p has a role in assembly of PTS (zeige PTS Proteine)-receptor docking complexes

  10. Results suggest that PEX3 (zeige PEX3 Proteine) plays a selective, essential, and direct role in class I peroxisomal membrane protein import as a docking factor for PEX19.

PEX19 Protein Überblick

Protein Überblick

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit PEX19

  • Peroxin 19 (Pex19)
  • Peroxisomal farnesylated protein (Bm1_19905)
  • peroxisomal biogenesis factor 19 (PEX19)
  • peroxisomal biogenesis factor 19 (Pex19)
  • BEST:GH03076 Protein
  • CG5325 Protein
  • D1S2223E Protein
  • DmelPex19 Protein
  • Dmel\\CG5325 Protein
  • HK33 Protein
  • PBD12A Protein
  • Peroxin-19 Protein
  • PMP1 Protein
  • PMPI Protein
  • PxF Protein
  • PXMP1 Protein

Bezeichner auf Proteinebene für PEX19

CG5325-PA , CG5325-PB , Pex19-PA , Pex19-PB , peroxin 19 , peroxisomal farnesylated protein , Peroxisomal farnesylated protein , 33 kDa housekeeping protein , housekeeping gene, 33kD , peroxin-19 , peroxisome biogenesis factor 19

GENE ID SPEZIES
34630 Drosophila melanogaster
6098885 Brugia malayi
5824 Homo sapiens
19298 Mus musculus
289233 Rattus norvegicus
521522 Bos taurus
100689302 Cricetulus griseus
100173241 Pongo abelii
Ausgewählte Anbieter für PEX19 Proteine (PEX19)
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